Laboratory of Cellular and Molecular Neuroscience

Laboratory of Cellular and Molecular Neuroscience (LCMN) @UTSScience
A/Prof Alessandro Castorina, Laboratory Head

[Laboratory of Cellular and Molecular Neuroscience @CastorinaLab]

Honoured to present at #ASMR2025 NSW with my Honours student Lilli Christie! We shared our work on PACAP signalling in brain health 🧠 & AZE toxicity in MS 🧬. Grateful for the Best EMCR Oral Award 🏆 & support from @MSAustralia + @RLCooperMedRes 💙 #MSResearch #EMCR

[Laboratory of Cellular and Molecular Neuroscience @CastorinaLab]

🧬 New microglia research!
We show VPAC1 & VPAC2 receptors play distinct roles in brain immune cells 🧠:
🔹 VPAC2 = stress protection under normal conditions
🔹 VPAC1 = resilience during inflammation
Could inform new therapies for #neurodegeneration.
https://t.co/VBbtaV49MP

[Laboratory of Cellular and Molecular Neuroscience @CastorinaLab]

Back again this year—but this time, I’m not alone.
Joined by Christabella, Ruby, Minduli & Salomie, we’re raising funds and awareness for MS. 💪🧡
Every donation counts. Let’s make a difference—together.

https://t.co/kKJO8yN0In

[Laboratory of Cellular and Molecular Neuroscience @CastorinaLab]

Incredibly proud of my students @minduliwithana, Chanelle Hazim, and Christabella Winata for their exceptional posters and Data Blitz presentations at #ANS2024! 🎉👏 Your dedication to advancing research on myelin disorders and potential treatments is inspiring. Keep shining! 🌟

[Laboratory of Cellular and Molecular Neuroscience @CastorinaLab]

Wonderful experience presenting my ideas for improved anatomy teaching at the 2024 UTS Learning and Teaching Forum along with other colleagues from @UTS_MedSci and other disciplines. #anatomy #education #UTS

[Laboratory of Cellular and Molecular Neuroscience @CastorinaLab]

Hippocampal neuroinflammation alters motivated behaviour in mice differently by sex. LPS increases neuronal activation in females but reduces it in males, disrupting memory and learning. 🧠🐁 #Neuroscience
Look it up 👇
https://t.co/dfZjRwBlXg

[Prof Deborah Marsh @djmarsh24]

Dual loss of #SMARCA2 #SMARCA4 is rare. PhD candidate @field_natisha in our gp leads an insightful review in #CancerLetters on disparate malignancies with this loss that impacts on #ChromatinRemodeling. #SWISNF #OvarianCancer #LungCancer. Read here:
10.1016/j.canlet.2024.217282

[Laboratory of Cellular and Molecular Neuroscience @CastorinaLab]

Another @rlcmrf funded study just off the press.

Differential Expression of PACAP/VIP Receptors in the Post-Mortem CNS White Matter of Multiple Sclerosis Donors https://t.co/hxwPGZzsIa #mdpiijms via @IJMS_MDPI

[Laboratory of Cellular and Molecular Neuroscience @CastorinaLab]

Finally out! Our work published in JNEUROCHEM showing that the neuropeptide PACAP, via the PAC1 receptor, protects the brain from myelin and axonal loss in the cuprizone MS model.
Thanks to the coauthors and the @rlcmrf for the funding support! 😊

Link below👇
10.1111/jnc.16199

[Laboratory of Cellular and Molecular Neuroscience @CastorinaLab]

Thanks to @NeuroimmOZ for inviting me to present at the 11th Neuroimmunology Australia workshop. Such an amazing experience, high-quality science and great people! 😊
Big thanks to the organizers @FabienneBrilot @JudithGreer @Markushofer Jacqueline Orian.

[Laboratory of Cellular and Molecular Neuroscience @CastorinaLab]

I'm taking part (for the fourth year) in The May 50K this May to support research into multiple sclerosis.

Now half way through, but haven't reached my $300 goal yet! 😟

Please sponsor my 100km challenge to leave MS behind! https://t.co/njTFaTR8vZ

[Laboratory of Cellular and Molecular Neuroscience @CastorinaLab]

This month, I'm running 100km in The May 50K to raise funds for research into multiple sclerosis.
And for today only, all online donations will be matched.
So sponsor me now and your donation will be DOUBLED! 💪💪💪
Please make a donation:
https://t.co/Xp5J6t9N4w

[Laboratory of Cellular and Molecular Neuroscience @CastorinaLab]

@Bradfield_Neuro Congrats Arvie! 😊😊😊😊

[Laboratory of Cellular and Molecular Neuroscience @CastorinaLab]

Hi,
if you study Multiple Sclerosis or any demyelinating disorder of the CNS, please consider submitting to this Special Issue.
Can offer significant discounts on APC for selected papers. 😊

[Laboratory of Cellular and Molecular Neuroscience @CastorinaLab]

@MS_Australia @nhmrc Congratulations to all these amazing MS researchers and the funding bodies for enabling these groundbreaking research projects! 😊💪

[Laboratory of Cellular and Molecular Neuroscience @CastorinaLab]

@LauraPiccio @nhmrc @Sydney_Uni Congratulations Laura!

[Laboratory of Cellular and Molecular Neuroscience @CastorinaLab]

@UTS_MedSci @UTS_Science @Molecules_MDPI Congratulations Ken!

[Laboratory of Cellular and Molecular Neuroscience @CastorinaLab]

@UTS_MedSci @AmaniAlghalayni @nhmrc Congrats @AmaniAlghalayni !

[UTS Medical Science @UTS_MedSci]

Associate Professor Alessandro Castorina, @CastorinaLab, leads the Laboratory of Cellular & Molecular Neuroscience @UTS_Science, where his group works on neurodegenerative disorders including #MultipleSclerosis. He's our Deputy Leader of Medical Science. #NationalScienceWeek

[UTS Medical Science @UTS_MedSci]

"Early Alterations of PACAP and VIP Expression in the Female Rat Brain Following Spinal Cord Injury" just out in the Journal of Molecular Neuroscience. Collaborative work from our Discipline's @CastorinaLab @DrCath1 @sarahtbneuro & others #SpinalCordInjury https://t.co/uRI6Njk7CF