Excited to finally share the #cryoEM structure of the iron #nitrogenase complex out today in @NatureSMB.
This thread serves to prime you on some of the amazing biochemistry required to make molecular nitrogen (N2) bioavailable!
https://t.co/jVOfeBUkn7
Meet the PyShell!🥧🐚 Diatom pyrenoids fix up to 20% of the Earth's #CO2🌏. We discovered that their Rubisco is encased in a tight protein lattice that is essential for efficient carbon fixation and cell growth🌱
Super excited to share our new preprint📜: https://t.co/zkYHHLbvBy
Excited to share our preprint: “Structural and mechanistic insights into Streptococcus pneumoniae NADPH oxidase” in which we obtained a structure of a 46-kDa membrane protein to 2.2 Å resolution without fiducials.
https://t.co/Cu2RxdxyZq
Come join us in Glasgow! These new posts will help us improve our service to users and make sure we are really wringing the most out of our instrumentation. I think there is still ground to cover with our CRYO ARM/Apollo combination and it'll be fun!
It is my pleasure to announce the @EMBO course on “In situ structural biology by Cryo-FIB and Cryo-ET” taking place @MPI_Biochem from 8.-14. April 2024. If you are interested in learning about cryo-ET and cryo-FIB including lift-out, apply by December 8th!
https://t.co/f2viL7tHhq
#CryoSPARC v4.3 is now available! ❄️⚡️
Featuring an all-new suite of #cryoEM data cleanup tools, new micrograph grid display and interactive job improvements, and a detailed performance benchmarking and comparison system!
Changelog: https://t.co/M3mLGtFhSS
1/5
When a student asks about number of turns of copper coil in an EM lens and you don’t know…. CM120: 588. Thanks to our #workshop@MPIbp ! @thermosciEMSpec#cryoEM
Outstanding talk @CTLSlifeScience#CLTS2023 Juan Garcia Vallejo @amsterdamumc
'Behind every user fee there is a personal/professional story'
Getting the financial model right in facilities makes a huge difference to individuals/projects. Ability to pay ≠ research quality
We suffered two problems on our Krios/Arctica instruments related to a pressure gauge called PPal. Here a picture of the faulty PPal from the Arctica. But then...what is a PPal and how it measures pressure? These two questions kept me busy for a while, a thread to follow 👇
Japan is one of only 4 countries to ever win the FIFA Women’s World Cup ⚽️🏆
And yet, less than a month out, there is no broadcast deal
Get the damn deal done,
FIFA & 🇯🇵 Broadcasters
Girls deserve something to aspire to,
The footballers deserve to be showcased
Get it done!
Here is Ray's paper associated with the PASR workshop introducing the concept of dithering from astrophotography to cryoEM to recover information past Nyquist as long as there is sufficient movement between frames. That's right - sample drift is good!
https://t.co/LvNappyksl