👋Channelomics.bsky.social👋

We love ion channels so much we've dedicated a twitter feed 2 them. @ us ur ion channel papers 4a RT. We don't sell stuff! Hoping 2go now where the sky is blue.

[👋Channelomics.bsky.social👋 @Channelomics]

FYI information, the @Channelomics .bsky.social Ion Channel feed is now flowing, this means if you follow us on there, any post you make (on that platform) including #ionchannel will be added to the Ion Channel feed.

https://t.co/acZGsZaflw

[👋Channelomics.bsky.social👋 @Channelomics]

Mechanism of conductance control and neurosteroid binding in NMDA #IonChannel receptors | Nature Sorry it is paywalled…. But look at the beautiful channels 🥲https://t.co/zi6HIwkiMY

via Mastodon

[👋Channelomics.bsky.social👋 @Channelomics]

Deletion of the TRPV1 #Ionchannels attenuates afferent renal nerve responses to renal artery occlusion but not elevated renal pelvic pressurehttps://physoc.onlinelibrary.wiley.com/doi/10.1113/JP289721?af=R

via Mastodon

[👋Channelomics.bsky.social👋 @Channelomics]

Substrate stiffness attenuates cardiomyocyte depolarization slope via sodium channel modulation (Increased stiffness of the substrate causes the dysfunction of Nav1.5 #Ionchannel kinetics) https://t.co/V0gWD0raJJ

via Mastodon

[👋Channelomics.bsky.social👋 @Channelomics]

Sclareol and cinnarizine are non-selective inhibitors of voltage-gated Cav1.3 L-type Ca2+ #ionchannels Open access. https://t.co/yby7oAh2jR

via Mastodon

[👋Channelomics.bsky.social👋 @Channelomics]

Mouse retinal ganglion cells and night blindness | TRPM1 #ionchannels, mGluR6 of retinal ON bipolar cellsJ.General Physiol. https://t.co/8HpJz2L6qp

via Mastodon

[👋Channelomics.bsky.social👋 @Channelomics]

Aberrant HCN4 #ionchannel expression: Impacts on neuronal excitability and implications for epilepsy pathogenesis - Spyrou - British Journal of Pharmacology Paywalled https://t.co/L2u3fquD8P

via Mastodon

[👋Channelomics.bsky.social👋 @Channelomics]

Piezo1 #ionchannels regulate the mechanotransduction of soft matrix viscoelasticity | Nature Communications https://t.co/aSWlvwv0Zi

via Mastodon

[👋Channelomics.bsky.social👋 @Channelomics]

Massive reduction of RyR1 #Ionchannel in muscle spindles of mice carrying recessive Ryr1 mutations alters proprioception and causes scoliosis - Ruiz - The Journal of Physiologyhttps://physoc.onlinelibrary.wiley.com/doi/10.1113/JP287832?af=R

via Mastodon

[👋Channelomics.bsky.social👋 @Channelomics]

Augmenting AMPA #IonChannel signaling after spinal cord injury increases ependymal-derived neural stem/progenitor cell migration and promotes functional recovery - Nature Neuroscience https://t.co/DxsMMDF1xt

via Mastodon

[👋Channelomics.bsky.social👋 @Channelomics]

Curious… what’s up?#IonChannelsExpression of Concern https://t.co/MsW320UtmK

via Mastodon

[👋Channelomics.bsky.social👋 @Channelomics]

Voltage-gated sodium #IonChannels: Mechanisms, disease, and a growing research community *Special Issue* Journal of General Physiology. https://t.co/GPoAwfgMLo

via Mastodon

[👋Channelomics.bsky.social👋 @Channelomics]

Fatigue arising from KATP SUR2 gain-of-function in Cantu syndrome mice Scala -> Nichols. £€$¥https://t.co/TOkoIihM40: Cantu syndrome -> muscle fatigue via overactive KATP #Ionchannels. Reversed by glibenclamide, suggesting possible new treatment.

via Mastodon

[👋Channelomics.bsky.social👋 @Channelomics]

A polycyclic scaffold identified by structure-based drug design effectively inhibits the human P2X7 #IonChannel receptor - Nature Communicationshttps://https://t.co/gfHiyBcoP2

via Mastodon

[👋Channelomics.bsky.social👋 @Channelomics]

Delta-type glutamate receptors are ligand-gated #ionchannels |Nature £$¥€https://t.co/H2GFdWRKYn

via Mastodon

[👋Channelomics.bsky.social👋 @Channelomics]

Distinctive GABA A #Ionchannel receptor subunit expression modulates cell specific EMT and functional responses in glioblastoma breast and ovarian cancer - Scientific Reports https://t.co/FT6wKVXSgb

via Mastodon

[👋Channelomics.bsky.social👋 @Channelomics]

Calmodulin binding is required for calcium mediated TRPA1 #IonChannel desensitization | Nature Communications https://t.co/VopfyGSNb9

via Mastodon

[👋Channelomics.bsky.social👋 @Channelomics]

TLDR: CBD alone doesn’t stop drug-resistant epilepsy. But paired with GABAergic meds like phenobarbital or diazepam, it cuts mortality and resistance. But combining with sodium channel blockers may worsen seizures https://t.co/schHFT8OwE

From @ChannelOmics.bsky.social

#IonCha…

[👋Channelomics.bsky.social👋 @Channelomics]

Don’t know why IFTTT screwed up the link 🥲

https://t.co/yNaQc5gBj5

[👋Channelomics.bsky.social👋 @Channelomics]

A conserved mechanism of LRRC8 #ionchannel inhibition by two structurally distinct drugs | Communications Biology https://t.co/hWLIivJhNF access

From @ChannelOmics.bsky.social

#IonChannels

[👋Channelomics.bsky.social👋 @Channelomics]

TRPM7 Deficiency Accelerates Vascular Senescence by Inhibiting H3K18 Lactylation - Wang - Aging Cell - Wiley Online Library https://t.co/ntJWDWGIdV

From @ChannelOmics.bsky.social

#IonChannels