Matthew Charman

Molecular biologist, virologist, cell biologist. Postdoctoral fellow at the Children's Hospital of Philadelphia.

[Hensley Lab @SCOTTeHENSLEY]

The Microbiology Department at Penn is hiring Professors of all ranks, and I'm co-chairing the search committee with @SunnyShinLab/@BettsLab.
Please RT and contact us if you have questions about the position and our department.
https://t.co/DR7un2bjue
https://t.co/CZ1d2RlNk8

[Matthew Charman @CharmanMatthew]

Congratulations to Nick Grams and @WeitzmanLab. I am looking forward to many more exciting discoveries on adenovirus packaging and biomolecular condensates in the near future!

[The EMBO Journal @embojournal]

Regulation of viral biomolecular condensates:
Phosphorylation in the intrinsically disordered region #IDR of #adenovirus protein 52K modulates its liquid-like properties and function in viral packaging
@WeitzmanLab and collaborators @PennMedicine
https://t.co/kbS8aTZZFj

[Michael J. Hogan @MikeHoganPhD]

*Please share!* The Hogan Lab (https://t.co/QWxQowXYLg) at Penn is hiring our first lab tech to start ~1/2/24. Topics include mRNA vaccines, viral immunology, and T cell protection. Job ad & instructions here: https://t.co/XJK4RBBtFY

[MRC-Uni of Glasgow Centre for Virus Research @CVRinfo]

📢VACANCY | 2 Senior Lecturer/Professor Positions

Are you leading a programme in virology complementary with our research programmes? Join the CVR team!

We encourage applications from women, minority ethnic groups & non-standard career paths.

https://t.co/rTQJSwQPut Ref 125249

[Alexander Price @PricelessSci]

Interested in the RNA biology of DNA viruses? So are we! Hopefully I captured that in this (first version) of a new Price Lab logo!

[Matthew Charman @CharmanMatthew]

@annasimsbiol @CVRHutchinson @AmerSocVirol Have fun! Go say hi to Nick Grams and Amber Abbott from @WeitzmanLab

[Alexander Price @PricelessSci]

Job posting is live for a research assistant/lab manager to join our new lab! Research will be focused on cellular RNA processing events hijacked by tumor-causing viruses. Please broadcast widely and reach out to me directly if you have any questions. https://t.co/5VUeld8wTo

[Daniel Beiting @hostmicrobe]

🚨Please RT!🚨 My lab is looking for a new Research Specialist to run our sequencing projects @pennvet! Previous folks in this role have gone on to PhDs and med/vet school. On-the-job training makes this a great opportunity for new grads 🎓! Apply below.

https://t.co/OTQdMSBDol

[Priya R. Banerjee @BanerjeeLab_UB]

We are excited to share our new work with you all 💧🔬🩸

"Heterotypic interactions in the dilute phase can drive co-condensation of prion-like low-complexity domains".
Spearheaded by a fantastic postdoc @richoodavis. A longer thread will follow soon.

https://t.co/fWhMXryVR8

[Digs @Digs66768072]

Fully funded PhD opportunities at the University of Edinburgh here - https://t.co/aiV8zeZa0v

Including one with Dr Richard Sloan and myself on viruses and IFITM proteins

[Matthew Charman @CharmanMatthew]

Fantastic findings that link microbiome, small RNAs, and inherited phenotypes. Congratulations all involved in this important discovery.

[Colin Conine @ColinConine]

Check out the new work lead by my lab @TakuKambayashi lab, and the Grice lab at UPenn. We found in mice that the microbiome and immune system regulate a variety of phenotypes in progeny transgenerationally and that this may occur by regulating small RNAs in the gametes.

[Rogue Virologist @RVirologist]

Proud of our new work showing that biomolecular condensates and phase separation control viral packaging through molecular grammar of a viral protein. "Isn't that how all viral assembly works?" you ask. Yes, yes it is. But CNS editors would think that sounds boring.

[Matthew Charman @CharmanMatthew]

@RVirologist Great point, but it may not be as simple as that. Take a look at this https://t.co/hSUrLzHPab or see my earlier tweets to explore why viral assembly may be more complicated than we thought.

[Nature Microbiology @NatureMicrobiol]

OUT NOW!

👉 A viral biomolecular condensate coordinates assembly of progeny particles by @WeitzmanLab and @CharmanMatthew published @Nature

https://t.co/WiuBYEo3VC

[Matthew Charman @CharmanMatthew]

Anyone familiar with adenovirus knows that this virus uses a lot of fascinating molecular biology to replicate, but some of our early follow-up findings are exceptionally intriguing!

[Matthew Charman @CharmanMatthew]

Thrilled to announce that our paper on adenovirus and biomolecular condensates was published today in @Nature. https://t.co/hSUrLzHPab. What a fantastic achievement from everyone involved! @WeitzmanLab. I am really excited about where this will take our future research!

[Matthew Charman @CharmanMatthew]

8. In follow-up studies we are investigating how viral biomolecular condensates are regulated, and how progeny assembly is initiated when two pathways (phase-separated capsid proteins and newly synthesized viral genomes) converge.