KUMedChem

Department of Medicinal Chemistry, University of Kansas - Lawrence

[KUMedChem @ChemKu]

The Department is happy to announce the promotion of Dr. Mark Farrell and Dr. Shyam Sathyamoorthi to the rank of Associate Professor. Congratulations!

[KUMedChem @ChemKu]

One more cover for the virtual wall: Farrell lab!

[KUMedChem @ChemKu]

Bloom Lab! 4/4

[KUMedChem @ChemKu]

Our virtual departmental wall was enriched substantially in the last few months with journal cover art highlighting recent publications from our faculty. Thread! 1/4

[KUMedChem @ChemKu]

Boskovic Lab! 3/4

[KU Pharmacy @KUPharmacy]

Prof. Emeritus Bob Hanzlik invested 49 years in the School of Pharmacy. His passion for mentoring students and junior faculty made an exponential impact in the pharmacy community. Former students, colleagues and others are now giving back. Read more https://t.co/Mg8SS55ldr #KURx

[J Org Chem/Org Lett @JOC_OL]

Welcome to another awesome pair of issues from @JOC_OL! This time in #JOrgChem we feature a cool cover of a “blueprint” for synthesizing complex lactones https://t.co/VIY2KDssD2. Meanwhile in #OrgLett we present a unique dihomohalogenation methodology https://t.co/5rx7g3iQY2 😃

[KUMedChem @ChemKu]

Congratulations to Boskovic lab team for this new publication in @angew_chem in which they literally shine light on small heterocyclic ketones.

[Zarko Boskovic @djavko]

I am very proud to share our most recent work, now accepted in @angew_chem. Good work @mannpharm, @pawandhote1 et al. Photochemical Decarbonylation of Oxetanone and Azetidinone: Spectroscopy, Computational Models, and Synthetic Applications https://t.co/xSLv08wylL

[KUMedChem @ChemKu]

Making cyclic peptides through a "Snip&stitch" strategy developed by the Bloom Lab.

[ACS Central Science @ACSCentSci]

Late-stage skeletal editing of peptide −SS− bonds through bis-dehydroalanine intermediates provides ready access to chemically unique −CC− carbocycles with enhanced biopharmaceutical properties https://t.co/mrUa1SvNgW

NEW #ASAP by Steven Bloom & Samuel Gary @ChemKu

[KUMedChem @ChemKu]

Congratulations to our 2022 Smissman awardee, Prof. Craig Crews! Thank you for the two invigorating lectures and a day of wonderful interactions with students and faculty.

[Craig Crews @CraigMCrews]

It was an honor to give this year's Smissman Memorial Lecture and I owe a big thank you to the KU Medicinal Chemistry Department for hosting me!

[KUMedChem @ChemKu]

Directing CAR NK Cells via the Metabolic Incorporation of CAR Ligands into Malignant Cell Glycans https://t.co/nhEpnqbQd2

[KUMedChem @ChemKu]

Highly Stereospecific Cyclizations of Homoallylic Silanols https://t.co/bz5SLgLZKb

[KUMedChem @ChemKu]

Ring Opening of Aziridines by Pendant Silanols Allows for Preparations of (±)-Clavaminol H, (±)-Des-Acetyl-Clavaminol H, (±)-Dihydrosphingosine, and (±)-N-Hexanoyldihydrosphingosine https://t.co/KWHh6CBsoW

[KUMedChem @ChemKu]

Congratulations to the freshly minted PhD from the department! Good luck at Scripps.

[FarrellLab @farrellglycolab]

#1

[KUMedChem @ChemKu]

The department celebrated 49 years of Prof. Robert Hanzlik's impact on science and community @UnivOfKansas with a symposium and a banquet. Congratulations, Bob!

[Mark Farrell @MarkPFarrrell]

Congratulations to @pross1193 on a successful PhD Defense today. To say I’m proud is an understatement. The body of innovative research that Pat completed is so impressive. Looking forward to seeing what Pat gets up to with @daniel_murin and beyond! @FarelChemImmuno PhD #1

[KUMedChem @ChemKu]

Target ID of small molecules using CRISPR: new technology from the Wang lab. Read in @ACSCentSci
https://t.co/Szs3gytoC3

[KUMedChem @ChemKu]

Congratulations to @Farrellglycolab members and @MarkPFarrrell for their most recent publication in ACS Chem Biol: Directing CAR NK Cells via the Metabolic Incorporation of CAR Ligands into Malignant Cell Glycans https://t.co/rcevo6Yw0G

[KUMedChem @ChemKu]

Boskovic lab @chemku reporting in J. Org. Chem. @JOC_OL their efforts to reach complex structures in short order from simple precursors.

[J Org Chem/Org Lett @JOC_OL]

Spirocyclic azetidine-lactones in a 7-step process with two key photochemical reactions: aza-Yang cyclization to make azetidinols and Buchner insertion of carbene into an aromatic ring to make lactone and cycloheptatriene. In #JOC from @djavko et al. https://t.co/kIPo8appfH