Chenchen Pan

[Ali Max Erturk @erturklab]

Want to use deep learning for image analysis but lack the coding skills? We introduce DELiVR, a game-changer in brain-wide cell analysis. No coding required, our Fiji Plug-in does the magic. Hats off to @Dorie00, @Rami96614090, @moritz_negwer! 🧵👇🏼 1/n https://t.co/pl7Hwvo2sp

[Ali Max Erturk @erturklab]

Imagine you could stain whole adult mice with standard IgG antibodies. What you couldn't do! We present wildDISCO technology for this🤗, creating the first whole body vascular, lymphatic, and nerve atlases. By @HongchengM @jieluo692 https://t.co/c2F91KQPv4 🧵👇🏼(turn on the sound)

[Ali Max Erturk @erturklab]

An unbiased study of whole biological systems is key to deciphering complexity. Our new paper describes the steps & applications of vDISCO whole mouse imaging in @NatureProtocols work by @MarikaRuiyao, @ilginkolabas et al. #vDISCO #clearing
https://t.co/PvdVnx8JOO 🧵👇1/n

[Matthia Karreman @MA_Karreman]

How do cancer cells manage to extravasate from brain microvessels, in order to form brain metastases?

We show that cancer-cell derived MMP9 induces remodelling of endothelial cells which supports early brain colonisation: now online @CR_ACCR https://t.co/oMc3WqyaZi

A 🧵👇

[Ali Max Erturk @erturklab]

Spatial-omics goes 3D🤗! Out at Cell @CellCellPress 👉🏼 We developed DISCO-MS with @labs_mann, a spatial proteomics technology for specimens fully imaged in 3D. DISCO-MS is aided by robotics and enables the study of diseases at their early stages. https://t.co/MyvXnnBDgL🧵👇

[Zhe Wang @ZheWang_NCB]

📢@NatureCellBio Enjoy this latest Perspective on the crosstalk between #cancer and #neuroscience by @ChenchenPan1 and Winkler from @Winkler_Lab
@NatResCancer

👉: https://t.co/P23Xl5iRjJ

[Eric Topol @EricTopol]

The road to cancer cures may go through the nervous system. An astute perspective on cancer-neuroscience interactions @NatureCellBio https://t.co/T4wEDD0O9B by @ChenchenPan1 @Winkler_Lab

[Chenchen Pan @ChenchenPan1]

Check out our latest Perspective online highlighting the milestone discoveries in Cancer Neuroscience and their clinical implications @NatureCellBio. Very grateful to work with the great team @Winkler_Lab. Looking forward to more discussions and collaborations on related topics!

[Varun Venkataramani @VarunVenkatara2]

Very happy that our latest Perspective is now online @NatureRevCancer ! We discuss implications of malignant, multicellular networks and potential therapeutic strategies how to disconnect them. Thanks to everyone involved ! #CancerNeuroscience #TumorMicrotubes #neurotwitter

[Ali Max Erturk @erturklab]

Our new paper describes the steps and applications of SHANEL tissue labelling, clearing, and imaging for 3D maps of human organs. In @NatureProtocols work by @HongchengM @zhouyi_rong @shan_heather. #SHANEL https://t.co/S5SPHkEB3I

[Ilgın Kolabas @ilginkolabas]

Check out our new preprint!!🤩🥳
We show how skull is more than a just a physical barrier to protect the brain.

I wonder what further mysteries will be discovered in the next years about this gem 💀🕵🏻‍♀️

[Ali Max Erturk @erturklab]

The skull is considered a physical barrier (helmet) for the brain. Our new findings show that the skull can be utilized to interact and monitor neuroinflammation in diverse brain diseases.
#scRNAseq #proteomics #skull #AI #clearing #TSPOPET
https://t.co/LpF3JgNXxk details🧵👇1/n

[Ali Max Erturk @erturklab]

Tissue clearing yields cool 3D images but not much molecular data. Not anymore🤗
Meet DISCO-MS enabling unbiased proteomics profiling of 3D-imaged organs. https://t.co/4iqetfV609
We co-developed with @labs_mann work by @HarsharanBhatia & @ADBxMPIB collab. with @fabian_theis🧵👇

[Ali Max Erturk @erturklab]

We used DISCO clearing to reveal hypervascularization of hypothalamic nuclei in the brains of high-fat diet mice compared to chow.
Collaboration with @CGarciaCaceres, @MatthiasTschop, work by @ChenchenPan1
https://t.co/0w1i8hRjsO
#DISCO #Motabolism #Vascular #VesSAP

[Ali Max Erturk @erturklab]

My interview with Miltenyi BioTec about tissue clearing, light-sheet microscopy and their applications in biomedicine 😀

[Cristina García Cáceres @CGarciaCaceres]

After long journey we are very excited to share our work in @Cell_Metabolism @IDO_Helmholtz @LMU_Uniklinikum Thank you to very talented @TimGruber14 and outstanding funding @DiabResearch @ERC_Research @SyNergy_Cluster and all collaborators https://t.co/YEcsehzFqi

[Ali Max Erturk @erturklab]

You have experience in proteomics and want to combine it with imaging and AI? Consider joining us!
We are a friendly and fun group, also very international and multidisciplinary.
https://t.co/AL2UQ0iIVf
#massspec #proteomics #clearing #humanorgans #organoids #deeplearning #ai

[Ali Max Erturk @erturklab]

Check out our VesSAP work in the current @naturemethods issue. This is a novel machine learning technology to segment complete mouse brain vasculature. It can readily be applied to any vascular data.
https://t.co/VDAGnc0lbq
#AI #deeplearning #machinelearning #vessel #3D

[Ali Max Erturk @erturklab]

1) We are super excited to present VesSAP with Bjoern Menze lab: a novel machine learning technology to segment complete mouse brain vasculature now online at @naturemethods
https://t.co/VDAGnc0lbq
work by @jocpae & @MihailMuc
#AI #deeplearning #machinelearning #vessel #3D

[Ali Max Erturk @erturklab]

All you need to know about 37 pdf pages of SHANEL paper in a 2 min animation (with sound).

Have more questions- feel free to post here, we're happy to answer.
#3D #imaging #AI #deeplearning @CellPressNews @CellCellPress https://t.co/EhlK8OwiNC