Chris Cho

antibiotic steward | ID PharmD at Providence St Johns | Philly ➡️ Los Angeles | #shorterisbetter 💊

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

Efficacy for prolonged infusion beta-lactam dosing schemes has been previously described, but there has been less focus on the safety of this strategy!
🆕��🔥 #IJAA
Meta-analysis on safety of standard vs prolonged infusion of beta-lactams #IDXposts
https://t.co/4aYffOWBvH

[Dr. AK 🇮🇳 @docakx]

🌟 MONKEY POX - Potential treatment options

https://t.co/mu2VsCxtaA

[AHN Infectious Disease/Critical Care Medicine @AHNidccm]

Check out our ASP Team’s latest newsletter!

💊🦠🆔 #idccm #IDCCM #ASP #AntimicrobialStewardship #IDforMe

[Open Forum Infectious Diseases @OFIDJournal]

New insights into the therapeutic management of Varicella-Zoster Virus meningitis: a series of 123 PCR-confirmed cases

✅ Just Accepted
🔗 https://t.co/qQOqIV7KN5

[Madison Salam, PharmD, BCIDP @madison_salam]

Yahoo!! Another article to support PO stepdown for Streptococcal bacteremias. Stoked to be a part of this excellent team!
https://t.co/siLMyZc9LD

[Timothy Li @drtimothyli]

Things We Do for No Reason™: S. pneumoniae and Legionella urine antigen testing

The authors suggest we should never order a S.pneumoniae UAT

For legionella UAT, it could be considered in severe CAP with risk factors or appropriate clinical syndrome

https://t.co/DQ1bHpexr9

[Helen Ding @HelenPharmD]

‼️Did you know that susceptibilities for many PO cephalosporins are inferred from cefazolin, not ceftriaxone? May overcall resistance but safest option if unable to test directly.

Removed cefdinir from our adult formulary and switched to cefuroxime. Here’s why! #downwithcefdinir

[Alice Han @dralicehan]

#IDtwitter
Anyone have experience with using pivmecillinam?

Surprised to read that it frequently maintains activity amongst esbl and CRE isolates.

Recently approved by US FDA.

Is there a catch?
https://t.co/aEhyeT0cJJ

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🆕️🔥Systemic review and meta-analysis
Ceftazidime-avibactam combination therapy versus monotherapy for treating carbapenem-resistant gram-negative infections #IDXposts
https://t.co/s1pb0X2hny

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🔥ORACLE🔥 @yourICM
@TrubianoJason
A Pilot RCT of Direct Oral Challenge(DOC) vs Routine Care in Low-Risk Penicillin Allergy in Critical Illnes
This study supports the safety & efficacy of DOC in low-risk[PEN -FAST< 3] penicillin allergy in ICU #IDXposts
https://t.co/8B0nyeeFl3

[Antibiotic Steward Bassam Ghanem 🅱️C����🅿️🌟 @ABsteward]

🆕️⚡️⚡️#JAC
Clinical outcomes in patients with pip/tazo-non-susceptible but ceftriaxone-susceptible E. coli or K. pneumoniae bloodstream infection
B/w What's the mechanism of resistance for such phenotype? #IDXposts
https://t.co/grDNS4Y7sH

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🆕️🔥Systematic Review & Meta-analysis
6 retros N:1746
Short Vs. Prolonged Duration of Therapy for Pseudomonas aeruginosa Bacteremia
No sig # in 30d mortality
Ongoing RCTs 7d Vs 14d:
SHORTEN-2
OPTIMISE
BALANCE
H/t @shorten2trial #IDXposts @BradSpellberg
https://t.co/j7uAdmKTjJ

[ACCP INFD PRN @accpinfdprn]

In a retrospective study, there was no difference in outcomes including 30 day mortality between linezolid and clindamycin in GAS infections. #MADID2024 @MAD_ID_ASP @SIDPharm @BaileyGarnerRx

[Contagion @Contagion_Live]

Dr. Thomas Lodise on the efficacy and safety of #cefiderocol in treating critically ill patients with carbapenem-resistant gram-negative bacterial infections. https://t.co/3nSAGPsEnq

[SIDP @SIDPharm]

Happy May! 🌼
Incase April was super busy for you, we put together a summary of interesting articles for you to check out. If you have any extra, please let us know in the comments!

[Open Forum Infectious Diseases @OFIDJournal]

Combination of anti-staphylococcal β lactam with standard therapy compared to standard therapy alone for the treatment of MRSA bacteraemia: a post hoc analysis of the CAMERA2 trial using a desirability of outcome ranking (DOOR) approach

✅ Just Accepted
https://t.co/urWUbi1sJq

[Michael Calderwood, MD, MPH @CalderwoodMD]

Another nail in the vancomycin coffin. After accounting for laboratory testing, pharmacist management time, and costs associated with vancomycin associated AKI, daptomycin saved $166 per patient when used in place of vancomycin. https://t.co/KPxCFBfAm3

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

Sneak peak of 🆕️🔥 @IDSAInfo/ @ESCMID SAB guidelines
🔆Risk stratification,high or low instead of complicated/uncomplicated
🔆Patients with high-risk features at baseline but TTE & PET/CT are negative, short course 14d
Slides shared @seanongwx
#ESCMIDGLOBAL2024
Oral Abx?!

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

ICYMI 🔥 FDA approved an updated label with additional data reinforcing the safety & efficacy profile of Biktarvy® to treat pregnant people with HIV-1 (PWH) with suppressed viral loads🔥
#IDXposts
https://t.co/iCzotilcOP