@p_happi_hq@liveUTIfree@cuticuk@ChronicUTI
Dear P Happi. Please let us know if you have been able to answer the following questions about your product:
1. What dose/how many bacteria is in each spray? 2. How do you know the bacteria are alive when they reach the vulva?
@RKhasriya@p_happi_hq@liveUTIfree@cuticuk We look forward to hearing the answers to those apposite questions. Thank you for asking them. Patients deserve to know what science backs the treatment that are suggested to them. It is in their best interest.
@p_happi_hq@liveUTIfree@cuticuk@ChronicUTI
Dear P Happi. Please let us know if you have been able to answer the following questions about your product:
1. What dose/how many bacteria is in each spray? 2. How do you know the bacteria are alive when they reach the vulva?
@GlobalUti “To date, the offerings are quicker ways of doing what is current. Currently we test for what we ill-understand. Should we do this faster then?”
— the late professor James Malone-Lee
https://t.co/A2GLjH8AuX
I enjoyed reading this. I do wish a wider debate were permitted. The insistence on point-of-care tests is starting to ossify into "fact". To date, the offerings are quicker ways of doing what is current. Currently we test for what we ill-understand. Should we do this faster then?
@vincristine@australiandr Note:
— UTI is a cause of retention.
— The diagnosis of IC requires the exclusion of UTI as the cause of the symptoms, so explaining away UTI via IC begs the question.
— The number of possible alternatives bears no necessary relation to their cumulative probability.
@LRH33@BundrickStewart A: "Fulguration" is being used as a term to create an aura of sophistication. It uses a heated wire as a knife to cut out the surface urothelium and some tissue that lies under it (submucosa).
(1) Why would you do that? We cannot get the advocates to answer that question.
@ChronicUTIAus@FutbolistaMedic@reverendofdoubt @DrLuisO @Weavofloxacin And those symptoms are sometimes not recognised as such.
“It is a myth that the elderly present without symptoms, as in asymptomatic bacteriuria. They have many symptoms but these are missed owing to the obsession with dysuria.”
https://t.co/0bZImpVOsB
@ChronicUTIAus “Many of the best practice recommendations for reporting centered around encouraging clinicians not to treat […] cultures with mixed flora”
A few moments earlier:
“It is a misnomer that urine is sterile; the healthy urinary tract has its own microbiome.”
There's so much to address in this article. We are totally on board with encouraging clinicians not to treat asymptomatic bacteriuria. But ignoring cultures with mixed growth and potential 'contaminants' is selective ignorance.
https://t.co/8qGRPUA8Sn
@ChronicUTIAus@GlobalUti@Peterpi30319529@cuticuk@cUTIrUTIAusNZ That would be consistent with the fact that the error does not occur when using https://t.co/B8k6GyBB5X (US) but does with https://t.co/qgQcBgw4sN (UK), but if that’s indeed what it is, a 405 error code is not the appropriate way to report it:
https://t.co/ctSqyaD5F8
THINK LIKE AN EPIDEMIOLOGIST:
Science is not magic. It always requires assumptions.
When done perfectly, some types of studies make fewer assumptions. But no one’s perfect.
We can’t decide quality from study type alone: a good observational study can be better than a bad RCT.
We thank the kind donor for her generous gift. It'll no doubt help nurture a generation of outstanding future scientists & advance #UTI research towards the goal that diagnosis of #chronicUTI becomes a thing of the past!
#PhDFellowship#FeelingGrateful 🤗 @RenalUCL
#BIIG Harry & Raj co-authored this review on why the simplistic/dichotomous interpretation of standard urine culture results is not sufficient/accurate for #UTI diagnosis in modern science.
Link: https://t.co/GJ7ErMzgjh
@RKhasriya@brubaker1030, @chai_toby R Moreland & A Wolfe