Circ: PHO

Circulation: Population Health and Outcomes, an American Heart Association journal. RT/follows do not imply endorsement.

[Circ: PHO @CircOutcomes]

For years, Circulation: Population Health and Outcomes has published research that helps shape cardiovascular health across communities and health systems. We're excited to announce Dhruv S. Kazi, MD, MSc, MS, (@kardiologykazi) as the next Editor-In-Chief.

[BIDMC Smith Institute @SmithBIDMC]

🆕 Aging into Medicare Advantage at 65 is associated with ⬆️ improvements in care affordability and satisfaction.

Read more from the Center for Health Policy’s @AndrewOseran et al. in @CircOutcomes 🔗 https://t.co/o3sKJJDZE0

[Circ: PHO @CircOutcomes]

ICYMI: Lp(a)FRONTIERS EXPANSION Study @kcferdmd et al
📍Presented at #ScientificSessions26
📝Simultaneous Publication in @CircOutcomes

Read More:
🔗https://t.co/HZDq6S45za @AHAScience

[Circ: PHO @CircOutcomes]

Sim pub #ScientificSessions26

1st dedicated RCT of Lp(a)-lowering therapy in US Black/African American &Hispanic adults w/ Lp(a) >125 & ASCVD

Lp(a)FRONTIERS EXPANSION (n=422),monthly pelacarsen 80 mg led to an 86% placebo-adjusted Lp(a)reduction at week 52 & was well tolerated

[Harpreet Bhatia @hsbhatia]

This trial demonstrates the feasibility of recruiting and retaining individuals typically underrepresented in cardiovascular clinical trials - Black and Hispanic individuals, and women. This study raises the bar and shows us what we should expect in clinical trials.

[Circ: PHO @CircOutcomes]

ICYMI: 📍Featured Science Presentation @ #ScientificSessions26 | Simultaneous Publication in @CircOutcomes

The Lp(a)FRONTIERS EXPANSION Study

@kcferdmd et al

🔗https://t.co/HZDq6S4DoI

[Circ: PHO @CircOutcomes]

Sim pub #ScientificSessions26

1st dedicated RCT of Lp(a)-lowering therapy in US Black/African American &Hispanic adults w/ Lp(a) >125 & ASCVD

Lp(a)FRONTIERS EXPANSION (n=422),monthly pelacarsen 80 mg led to an 86% placebo-adjusted Lp(a)reduction at week 52 & was well tolerated

[Circ: PHO @CircOutcomes]

Don't miss the accompanying Editorial by @hsbhatia:
Lp(a)FRONTIERS EXPANSION: Raising the Bar for Cardiovascular Clinical Trials #ScientificSessions26

🔗https://t.co/GQIzk73uBT

@AHAScience @kardiologykazi @iamritu @kcferdmd

[Circ: PHO @CircOutcomes]

Sim pub #ScientificSessions26

1st dedicated RCT of Lp(a)-lowering therapy in US Black/African American &Hispanic adults w/ Lp(a) >125 & ASCVD

Lp(a)FRONTIERS EXPANSION (n=422),monthly pelacarsen 80 mg led to an 86% placebo-adjusted Lp(a)reduction at week 52 & was well tolerated

[Circ: PHO @CircOutcomes]

🔗https://t.co/HZDq6S4DoI

📌Featured Science Simultaneous Publication #ScientificSessions26

📝Article by @kcferdmd @FaRodriguezMD @DrMichaelShapir et al

@ducciobaldari @WFCardiology @TulaneMedicine @iamritu @AHAScience @kardiologykazi @bnallamo

[Circ: PHO @CircOutcomes]

Sim pub #ScientificSessions26

1st dedicated RCT of Lp(a)-lowering therapy in US Black/African American &Hispanic adults w/ Lp(a) >125 & ASCVD

Lp(a)FRONTIERS EXPANSION (n=422),monthly pelacarsen 80 mg led to an 86% placebo-adjusted Lp(a)reduction at week 52 & was well tolerated

[Circ: PHO @CircOutcomes]

In 10362 @AllofUsResearch Ppts w/ @Fitbit data, each 1-SD (29-min) rise in night-to-night sleep duration variability linked to 24% higher composite CVD risk (HR 1.24) HR for HF (1.32) HTN(1.6) DM2 (1.20)
Mean sleep duration was not
@UMmedschool @umms @BostonChildrens
@harvardmed

[Circ: PHO @CircOutcomes]

📌Sim Pub with #ScientificSessions26

Sleep consistency matters more than sleep quantity?

🔗https://t.co/J2cRHDqeCn

Read More ⬇️

[Circ: PHO @CircOutcomes]

Concomitantly, major adverse event readmissions decreased (1.74 → 0.9/100 pts)

(🧵3/3)

[Circ: PHO @CircOutcomes]

📌Sim Pub with #ScientificSessions26

Can quality improvement programs result in improved survival among single ventricle infants?

🔗https://t.co/HR1DQl5mle

Read more⬇️ (1/3🧵)

[Circ: PHO @CircOutcomes]

New study from 77 centers of 5,495 infants w/ this condition showed enrollment in the NPC-QIC resulted improved interstage survival b/w stage 1&2 surgical palliations from 90.5% to 94.8% & remained at this level for nearly a decade (2016-2025)

(🧵2/3)

[Circ: PHO @CircOutcomes]

~ 1/5 on LLT take supplements even though guideline advises against them

Read Online Here: 🔗https://t.co/9rpDua3eej

@s_mangalesh
@pagingdrquds
@AnnMarieNavar

[Circ: PHO @CircOutcomes]

📌Sim Pub with #ScientificSessions26

Cross-sectional study representing 147.3 million U.S adults (NHANES, 2015-2020) finds that among those recommended for lipid-lowering Rx (LLT) by guidelines, 12.8% use supplements instead ~4.2 million folks.

Read more ⬇️

[Circ: PHO @CircOutcomes]

Novel findings: parents’ limited English sometimes supported patient engagement; caregiver support can build or limit independence. To improve care, target access to ACHD clinics, hand-offs & education
🔗https://t.co/2IH4Fx6gSZ

📝Article by @AnuAgarwalMD @MegumiOkumura et al

[Circ: PHO @CircOutcomes]

📌Sim pub #ScientificSessions26

Qualitative study creates #ACHD Care🎡 of 6 interdependent categories that shape care and emphasizes system structure, education, and support.

Read more⤵️

[Circ: PHO @CircOutcomes]

Our Journals work together to rigorously and rapidly review essential research for simultaneous publication during #ScientificSessions26

The result? Nearly 44 peer-reviewed studies published across 4 journals.

Check out the latest at https://t.co/q4J0i4L9H6

[Circ: Heart Failure @CircHF]

📌Sim Pub w/ #ScientificSessions26:

Can digital health accelerate GDMT optimization?

Randomized ENGAGE-HF trial shows improved #GDMT optimization at 90 days:

83.7% vs 74.0% (P=0.010)

Greater uptake of MRAs & SGLT2 inhibitors

A promising approach to post-discharge HF care

[Circ: PHO @CircOutcomes]

Our Journals work together to rigorously and rapidly review essential research for simultaneous publication during #ScientificSessions26

The result? Nearly 44 peer-reviewed studies published across 4 journals.

Check out the latest at https://t.co/q4J0i4L9H6

[Circ: PHO @CircOutcomes]

In a world of AI and LLMs, does great writing still matter? Absolutely. Hear from a Nobel Laureate and top medical journal editors on developing communication skills that drive impact.
📅 Nov. 8 | 🕜 3:15-4:30 PM CT | 📍 S100A
Add it to your #ScientificSessions26 schedule