Proud to announce my latest preprint, the culmination of my dissertation research defended two weeks ago! As co-first author, I'm excited to share the "dynamic 1D search and processive nucleosome translocations by RSC and ISW2 chromatin remodelers". https://t.co/EkMjg7qGgF
Look at this awesome processivity of chromatin remodeling enzymes! Green for nucleosomes and red for remodellers (RSC & ISW2). Note that we had to strobe green excitation for Cy3 due to its rapid photobleaching whereas JFX554 (@rhodamine110) survives the entire episode.
A well deserved accomplishment for this outstanding young investigator! Congrats @AlbertoMarinG1 & @rogerszou for the exciting work already paving the way for many more.
Claudia Carcamo @BCMB_JHMI had a beautiful work her discovery of 1D diffusion of a chromatin remodeler published in @eLife. Wonderful collaboration with Carl Wu!
https://t.co/t1arlhvC17
Our structures of nucleosome-bound Yamanaka factor Sox2 and Sox11 elucidate how pioneer factors invade chromatin for differentiation and development.
https://t.co/ypkUInxsGu