Pakistani Clinical Knowledge (PCK) Official

PCK is an educational forum of doctors from Pakistani Heritage working across the globe, with 30thousands doctors in Facebook forum Pakistani Clinical Knowledge

[Pakistani Clinical Knowledge (PCK) Official @ClinicalPck]

#AtypicalBacteria (like viruses) are too small, no cell wall and no energy system, hence obligate intracellular. Hence,can’t do: microscopy,gram stain,or culture. Only Antigen or antibody for diagnosis.Only mononuclear can kill them.Cell wall antibiotics don’t work.
ASIF HUSSAIN

[Pakistani Clinical Knowledge (PCK) Official @ClinicalPck]

Many drugs starting with letter “C���, can cause #Cytopenia (#neutropenia). Examples:
#Carbimazole
#Carbamzepine
#Chlorpropamide
#Chloramphenicol
#Colchicine
#Cancer chemotherapeutic
Mechanism is different for each but if it starts with C, look if it causes Cytopenia.

[Pakistani Clinical Knowledge (PCK) Official @ClinicalPck]

Great effort by our colleague aimimg to create awareness on management of burns.

[Pakistani Clinical Knowledge (PCK) Official @ClinicalPck]

#ThiazidesDiuretucs makes #Diabetes and #lipid profile worse by affecting #K-dependent Insulin secretion from beta cells. They also cause #hypercalcemia by increasing its absorption. They lose K, Na & water, and #Renal Disease. They are good for BP, Hyoercalciuria & DI.
Dr Asif

[Pakistani Clinical Knowledge (PCK) Official @ClinicalPck]

Last few months have been very challenging for health professions, PCK team is pround of our colleagues for their services during Covid Crisis.We wish you a happy and blessed Eid and pray for your safety in next coming days.
Dr Naeem Ashraf

[Pakistani Clinical Knowledge (PCK) Official @ClinicalPck]

#GrowthHormoneAndHypertension: GH increases angiotensinogen production from kidneys, hence causes high BP. GH related metabolic changes are earlier and more prominent than structural changes in adult human. #EndocinalHypertension.#Acromegally #Hypertension
Dr.Asif Hussain

[Diabetes UK Research @DUK_research]

Today is Insulin Appreciation Day, on the anniversary of Frederick Banting and Charles Best isolating insulin for the first time in 1921. Thanks to their research, countless people around the world have used insulin to manage their diabetes over the last century

[Pakistani Clinical Knowledge (PCK) Official @ClinicalPck]

Diabetes Nephropathy: eGFR 30 or below, it’s better to avoid:
1: Metformin
2: SGLT2 Drugs (eGFR below 45):
4: DPPV 4 Drugs such as Sitagliptin . Linagliptin is metabolised in Liver.
5: GLP-1 Drugs (especially long acting) #DiabeticNephropathy #antidiabeticdrugs
Dr Asif Hussain

[Pakistani Clinical Knowledge (PCK) Official @ClinicalPck]

#SecondaryHypertension #ResistantHTN: Most common cause is Reno-vascular. Weight change(gain or loss) is common if it’s due to endocrine cause.

Dr Asif Hussain

[The BMJ @bmj_latest]

Palliative care is often misunderstood as only being for people who are dying. Yet relieving suffering is an essential part of care for all patients with life threatening illness. How can the palliative approach be used in patients with severe covid-19? https://t.co/gvpa7NS7cU

[Pakistani Clinical Knowledge (PCK) Official @ClinicalPck]

Positive core antibody for Hep B (HBc Antibody) means that patient has HBV, either in the past which has recovered OR still going on.
HBsAg &/or DNA negative: recovered.
If HBsAg or DNA positive; means patent is still having infection. There is no role of vaccine. #HBV, #HBcAb

[Pakistani Clinical Knowledge (PCK) Official @ClinicalPck]

Women born with no uterus (MRKH), severe uterus malformation or adhesions or adenomyosis or uterus removal due to severe bleeding etc etc could have transplanted uterus from a deceased or alive donor.

Dr Sibte Hassan

[Pakistani Clinical Knowledge (PCK) Official @ClinicalPck]

Sad day for Nishtarians and health professionals, Prof Mustafa Kamal Pasha VC Nishtar Colledge and renowned surgeon passed away.

He was on ventilator for few days but lost the battle against Covid-19, May his soul rest in Jannah.

[Pakistani Clinical Knowledge (PCK) Official @ClinicalPck]

Risk management in health care setting means minimising the risk to our patients by:
1: Education, training and continious professional development.
2:Clinical audits
3:Evidence based care
4:Staffing and Staff management
5:Patient experience and involvement in care.
Naeem Ashraf

[Pakistani Clinical Knowledge (PCK) Official @ClinicalPck]

Fatty Liver disease

❗REASON.
👉Sedentary lifestyle
👉 Diabesity.
👉Hereditary

❗DIAGNOSIS

👉Exclusion
👉Imaging
👉Histology.

❗TREATMENT
👉Lifestyle changes.
👉 Medicine.
👉 Bariatric intervention in selected cases.

❗MONITORING
👉AST/ALT Ratio
👉Fibroscan.
ANJUM

[Pakistani Clinical Knowledge (PCK) Official @ClinicalPck]

Epilepsy is disease of grey matter (cell bodies) of Cerebral Cortex. Hence diseases affecting white matter (eg MS) or basal ganglia (eg Parkinsonism), or cerebellum, or brain stem or spinal cord can’t explain epilepsy. Dr Asif Hussain

[Partha S Kar 🇮🇳🇬🇧🏏🎥 @parthaskar]

If you are looking for indications of hope?
You will recall the dark and desperate times in Lombardy - reported by @sima_kotecha

Such joyful news from today

UK infection and death rates continue to fall- let’s all keep doing the basics of social distancing etc

#COVID19 🤞

[Pakistani Clinical Knowledge (PCK) Official @ClinicalPck]

Autoimmune diseases more common in female are associated with MHC -2 (HLA-D ) and those more common in men are associated with MHC-I (HLA-A,B or C) abnormalities. Dr Asif Hussain

[The BMJ @bmj_latest]

Should doctors tackling covid-19 be immune from negligence liability claims? Or despite extraordinary times, does immunity send the wrong message about practice standards? Read both sides of the argument in this #HeadToHead debate https://t.co/d2qVtIrjUV
@the_mdu @ProfMiola