We should use our unique human intelligence to solve challenges we face, and never give up or tell ourselves there's no hope. If we have a positive goal and we're well-motivated to seek the well-being of others, no matter how difficult it is to achieve, we can remain determined.
Happiness derived from mere physical comfort tends to be shallow and fleeting. It fails to pacify anxiety and fear. Whereas if we have a calm mind it is effective in overcoming even physical pain, therefore we should not neglect the inner values that are a source of a calm mind.