Annual killifish make neutrophils before almost every other cell type, even before gastrulation. Neutrophils usually arise from the lateral plate mesoderm (forming in cyan), but in killifish they are already patrolling around the embryo in gold. https://t.co/GeOzVd9H9M
Beyond thrilled to present our O-MAP—now *published* @naturemethods (!!!)
O-MAP is a powerful new method for biochemically "dissecting" the subcellular microenvironment around an RNA of interest, using off-the-shelf parts and standard manipulations. 🧵
https://t.co/gBGsQ6dBs9
Incredibly proud to share that I recently joined @UCSF_BTS@UCSF as an Assistant Professor! This means that the Calderon Lab is now open!
Or, more accurately, in the process of opening as I am still unboxing equipment and unraveling giant posters (a last @JSHendure lab gift) 🥳
We had an intense but exciting week guiding scientists from around the world into the multidimentional universe of spatial omics. Great experience to organize this EMBO practical course for imaging-based spatial omics together with @AlvaroCrevenna and @PerlasEmerald at @EMBLRome
Last day at the #EMBOSpatialOmics course in Rome. 🥳
Today we will have another round of practical sessions and data analyis exercises. 💻🔬
@SinemKSaka1, @AlvaroCrevenna and many speakers and students present techniques regarding SABER wash, imaging, ISS, RCA, PER...
This week at EMBL Rome we’re hosting our first EMBO Practical Course!
Participants started their journey in the world of imaging-based spatial-omics, with hands-on practicals covering every step from sample prep to data analysis.
#EMBOSpatialOmics
https://t.co/m5qZkkxv54
Excited to share our new preprint at bioRxiv!🎉 Decode-PAINT, a multiplexed in situ method to visualize multiple discrete genomic regions at a resolution close to the nucleosome scale. My postdoc project in Peng Yin lab @wyssinstitute with @oligopain 1/11
The peer-reviewed version of DNA Ticker Tape (now “DNA Typewriter”) is out today! During revision, we have expanded our lineage recording demonstration by integrating DNA Tape recording with single-cell RNA-seq (1/8)
https://t.co/wVKkT5CL4f
Amazing to see light-sheet + cleared tissue imagery on the cover!! Thank you to all co-authors for jointly working on this rewarding project, and grateful to @naturemethods for highlighting our work!🙏
I am delighted to share THE LORAX, a method which combines cell lineage trees (get it? 😉), scRNA-seq, & scATAC-seq to explore the underpinnings of clonal cell heterogeneity! (1/12)
https://t.co/1tFqLNzJ5w
Short thread on our latest work, from the incredible @CXchengxiangQIU (CX Qiu), entitled "Systematic reconstruction of cellular trajectories across mouse embryogenesis", which is out today in @NatureGenet. Link to accessible version: 1/n
https://t.co/pTInn5ld2P
Happy to share Paint server and homology optimization pipeline (PaintSHOP), an interactive platform for the design of FISH experiments. PaintSHOP democratizes and standardizes designing complex probe sets for the oligo FISH community. https://t.co/O4h8k5p7T4
Our latest preprint, from the brilliant @CXchengxiangQIU, systematically integrates a series of single cell RNA-seq datasets that collectively span mouse gastrulation and organogenesis (E3.5 – E13.5) (1/4)
Thank you for coming to our product reveal! #AGBT20. Visit us in Osprey 2 to learn more about our platform and the Select Release Program, https://t.co/FxfGJQgstX. #AGBT2020
Thank you @agbt, #AGBT20! We were thrilled with the excitement of our RC2 Platform and products for true spatial #sequencing. We can't wait for next year! (Pictured: Unveiling of our RC2 Platform), #genomics#spatialsequencing, Learn more: https://t.co/FxfGJQgstX