Diego Calderon (diegoisworking@bluesky)

Assistant Professor @UCSF_BTS | @CZBiohub – SF Investigator | trying out diegoisworking@bluesky

[Diego Calderon (diegoisworking@bluesky) @diegoisworking]

Incredibly proud to share that I recently joined @UCSF_BTS @UCSF as an Assistant Professor! This means that the Calderon Lab is now open!

Or, more accurately, in the process of opening as I am still unboxing equipment and unraveling giant posters (a last @JSHendure lab gift) 🥳

[Brunilda Balliu @brunilda_balliu]

1/ Our new paper is out in @CellGenomics 🎉
We introduce FastGxC, a fast and powerful method for mapping eQTLs in bulk and single cell sequencing studies and quantifying how their effects vary across tissues and cell types.
https://t.co/9y5pxJ8fLf

[Junyue @junyue_cao]

🚀Excited to share our new paper @Nature! We developed PerturbFate platform to discover how diverse genetic perturbations converge on a shared cell state, and key molecular programs driving it, led by our incredible student @xu_zxu from @RockefellerUniv.
https://t.co/NLHUVIB6Dg

[Aki Ushiki @AkiUshiki]

Our bat–mouse limb paper is now on bioRxiv! 🦇🧬https://t.co/0YL5oXiy7l

This was a collaborative effort across the @NadavAhituv, @NicolaIlling, @DoritHockman, Guy Kelman, Tommy Kaplan and my lab at @WashUGenetics

Highlights below ↓

[Chengxiang Qiu @CXchengxiangQIU]

New preprint! @JShendure @CXchengxiangQIU Can we learn regulatory grammars of human cell types we'll never be able to profile - by training on mouse development and transferring across 241 mammalian genomes?https://t.co/sWCWoAqJ2B

[Troy McDiarmid @TroyMcDiarmid]

Stoked to announce that I’m starting a lab as an Assistant Professor in the School of Biomedical Engineering and Centre for Brain Health at UBC!

https://t.co/e9ITKmsy1h

Recruiting at all levels - please share the word!

Cheers and happy long weekend all!

[UCSF Surgery @UCSFSurgery]

‼️The @UCSF Broad Stem Cell Center & Department of #Surgery is recruiting faculty to help advance the future of Gene Editing. This position focuses on the Development of delivery tools for Gene Editing to enable cutting-edge gene therapies.

Apply below👇https://t.co/ZE0UnxS5YP

[Rajiv McCoy @rajivmccoy]

Pregnancy loss is common in humans, and chromosome abnormalities are the leading cause. Using genetic data from ~140,000 IVF embryos, we show that common variation in meiosis genes influences recombination and aneuploidy risk.

@saracarioscia @aabiddanda

https://t.co/Lf1yBZFQkt

[Daphna Rothschild @D_Rothschild_]

Ribosomal RNA (rRNA) genes are found in hundreds of copies in the human genome.

Do sequence variations in these paralogs change the ribosome function? Yes!

I am excited to share our new preprint @mbarnalab @jkpritch in collaboration with Calico:
https://t.co/Hc6JH66C5Q

1/8

[Chengxiang Qiu @CXchengxiangQIU]

Thrilled to share I’ve started my lab at Dartmouth’s Geisel School of Medicine! We focus on mapping cellular trajectories & TF networks in development and Mendelian disorders, exploring new therapies. Join us—postdocs, grads, and scientists welcome! https://t.co/8lHVDt3dHP

[Troy McDiarmid @TroyMcDiarmid]

Stoked to share our latest work entitled “Large-scale discovery of neural enhancers for cis-regulation therapies”

https://t.co/zBSFtRHAbP

This is an enormous team effort that I had the honour of spearheading with Nick Page and @FloChardon

Tweetorial below.

[Molecular Cell @MolecularCell]

Online Now: Combinatorial mapping of E3 ubiquitin ligases to their target substrates https://t.co/T4aPvUHn08

[Dr. Barbara Stranger @be_stranger]

Please re-tweet:

We are hiring! Assistant Professor in statistical genetics. Also, hiring a postdoc. Reach out to hear more. Also, if you’ll be at #ASHG24 #ASHG2024, we could meet. https://t.co/OLHRllzBQl

[Yi Fu @Yi__Fu]

Excited to share my PhD work in @Agnelsfeir’s lab describing a method to engineer mitochondrial DNA deletions in human cells and our exploration of how cellular metabolism and transcription respond to deletion heteroplasmy. https://t.co/yK2ns3YpiJ 1/19

[Silvia Domcke @sdomcke]

New synthetic biology / gene regulation lab opening in Zurich! We’re studying how to control cell state transitions – for example, making diseased cells healthy or creating new cellular functions – using systematic perturbations, single-cell genomics and machine learning. 🧵1/4

[Harold Pimentel @hjpimentel]

This is happening tomorrow! Still some time to sign up! Both in-person and online opportunities!

https://t.co/l1FpnlYB3j

[Ryan Hernandez @rdhernand]

Thinking about a PhD using computational power to answer pressing problems in biology and health? @UCSF Biological and Medical Informatics PhD program is recruiting for Fall 2025! Join our info session next Monday Oct 21: https://t.co/jLMUwigeI1.

[Elphege Nora Lab at UCSF @ElphegeNoraLab]

First preprint from the lab 🚨

How can enhancers regulate target promoters across vast genomic distances, and what is the role of cohesin loop extrusion in the process?

https://t.co/l7bwPsTSkd

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[Mariano Martín @mamartin_ok]

The VESS organizing committee is looking for new members! If you are navigating the universe of variant effects and would like to get involved with @varianteffects seminars, contact us!

[Troy McDiarmid @TroyMcDiarmid]

Beyond stoked to share our latest, entitled “Diversified, miniaturized and ancestral parts for mammalian genome engineering and molecular recording” !

https://t.co/8BtGh7th6P