Tiago Cordeiro

Scientist @itqbunl, working on disordered proteins and related challenges.
PI of the Dynamic Structural Biology Lab aka Cordeiro Lab

[Tiago Cordeiro @CordeiroLab]

Spaghetti-like #disorderedproteins

[ITQB NOVA @itqbnova]

#ITQBNOVA’s Open Day is back! 🧪✨

Explore our science with lab visits, talks, experiments, a scientific escape room and more!

📅 March 15 (Sat), 10am-5pm
🎟️ Free entry

Visit us and bring your family and friends!

Stay tuned for details.

@OeirasValley @NOVAunl

[Pedro Domingos @pedromndomingos]

Fbxo42 promotes the degradation of Ataxin-2 granules to trigger terminal Xbp1 signaling https://t.co/3FQmWgJynp

[Tiago Cordeiro @CordeiroLab]

🚨 New preprint alert! 🚨 We uncover key aspects of how the #SARSCoV2 nucleocapsid protein self-assembles and undergoes LLPS—critical for viral behavior. Using #SAXS and #NMR, we reveal how disordered regions drive complex formation. Explore the details: https://t.co/G8DBj7IGwN

[Tiago Cordeiro @CordeiroLab]

As someone who works in protein chemistry and structure, I’m thrilled to see the 2024 #NobelPrize in Chemistry awarded to David Baker, Demis Hassabis & John Jumper. Their work is transforming the field. Congrats to all! #ProteinChemistry #NobelPrize2024

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

[Ana Sofia Pina @AnaSofiaPina1]

Don't miss the opportunity to participate in such a great event for peptide chemists: the XIX Iberian Peptide Meeting in Santiago de Compostela.

[Chris Ing @jsci]

Boy: Do not try and bend the protein. That's impossible. Instead... only try to realize the truth.
Neo: What truth?
Boy: There is no protein structure.
Neo: There is no protein structure?
Boy: Then you'll see, that it is not the protein that bends, it is only yourself.

[Kresten Lindorff-Larsen @LindorffLarsen]

Get your applications in before Oct 1st
https://t.co/ed2bZTLEok

[IUBMB @iubmb]

Bacteria that turn water into ice❄️ 🔬

Pseudomonas syringae contains special surface proteins that act like scaffolds for ice nucleation!

#science #research #microbiology #biochemistry

[Tiago Cordeiro @CordeiroLab]

Excited to share that @CordeiroLab presented our latest research at #IBSBC2024! A great opportunity to showcase our work @itqbnova and connect with fellow scientists and friends.

[Instruct-ERIC @instructhub]

Now that’s what we call an integrated structural biology community

[Stephanie Wankowicz @stephanie_mul]

We were incredibly disappointed with the lack of code or executable accompanying the publication of AF3 in @Nature . This contradicts scientific principles of the ability to evaluate, use, and build upon existing work. https://t.co/8fOYWffXLv

[PDA ITQB NOVA @PDA_ITQB_NOVA]

Summer Science @itqbnova is waiting for you! ☀️🧪

If you're an undergraduate student, from July 15-19th you'll get the chance to develop a lab project & take part in our social activities. 🌊

Apply by June 10th: https://t.co/g1f7pmensV .

@NOVAunl @OeirasValley

[ArraianoLab @ArraianoLab]

No #DiaInternacionalDaMulher queria partilhar um artigo que escrevi há dias sobre a Ciência e as Cientistas em Portugal!

[Tiago Cordeiro @CordeiroLab]

3/3 In eukaryotic cells, protein disorder is critical for signaling and regulation. Although intrinsically #disorderedproteins (IDPs) are a small fraction of typical bacterial proteomes, Tir helps us make the case that IDPs have a critical role at the host-bacteria interface.

[Tiago Cordeiro @CordeiroLab]

🎉 Exciting news! Our paper, "The Pathogen-Encoded Signaling Receptor Tir Exploits Host-Like Intrinsic Disorder for Infection" is officially published! @CommsBio,📚 Grateful for the collaboration and hard work of all involved. Read it here: https://t.co/aynMIJkO5K

[Tiago Cordeiro @CordeiroLab]

2/3 Using various state-of-the-art biophysical methods (#SAXS, #NMR #microscopy), we show that Tir, a bacterial effector, exploits host-like disorder to rewire cellular processes via dimerization, lipid binding, and phosphorylation, revealing a versatile strategy for infection.

[Tiago Cordeiro @CordeiroLab]

1/3 Have you ever wondered how pathogens hijack the host? 🦠 In our latest research, conducted in collaboration with @itqbnova, @LeibnizFMP, @NetBioinfoMRS, and @TheFrankelLab, we delve into the fascinating world of host-pathogen interactions.

[Kresten Lindorff-Larsen @LindorffLarsen]

Happy to share the publication of our paper in @Nature

Conformational ensembles of the human intrinsically disordered proteome

Work led by @GiulioTesei and @AnnaIdaTrolle. I'll post more later, but for now here is a link:
https://t.co/b3aZ6BbGpB
and a short movie about the work

[xavier salvatella @xsalvatella1]

@shaharsu I just read a paper where the authors show how structural biases in IDP ensembles found in vitro are recapitulated inside human-derived cells, you should check it out @shaharsu ! https://t.co/5AbyIwb9Jh

[Tiago Cordeiro @CordeiroLab]

Congratulations to Guillem Hernandez Gras on the successful completion of his PhD in #MolecularBiosciences @itqbnova! 🎓👏 It's been a privilege to supervise his impactful research on 'Structure and Dynamics of Pathogenic Scaffold Proteins.'

[ITQB NOVA @itqbnova]

Congrats to Guillem Hernandez Gras for his PhD in #Molecular Biosciences! 🎓👏

His #research, “Structure and Dynamics of Pathogenic Scaffold Proteins”, was supervised by #ITQBNOVA researcher Tiago Cordeiro.

@CordeiroLab @NOVAunl @OeirasValley
#TeamNOVA #MolBioS