Cortexa Therapeutics

With urgency and precision, we’re accelerating breakthrough science —because in neurodegenerative diseases, time is everything.

[Cortexa Therapeutics @CortexaTx]

🔎CP-AMPARs distort signal precision. 🧠🆕Nature study shows removing them from PV interneurons sharpens selectivity—not dulls it. Big validation for @CortexaTx's #ALS strategy: fix the calcium leak, restore the signal. Hope, grounded in mechanism.
https://t.co/bp3Q8EYWxC

[Cortexa Therapeutics @CortexaTx]

🧠🥛 Still deep in the calcium–excitotoxicity–mitochondrial failure loop. New research from Dr. Bading’s team at Heidelberg zeroes in on TRPM4’s toxic role. Their use of FP802 aligns with Cortexa’s strategy—and might confirm a🔑breakthrough.
🔗 https://t.co/S8D1cjwdg5

[ALS TDI @ALSTDI]

May is ALS Awareness Month. Stay tuned throughout the month for quotes from our ALS community about their ALS journey and why we must continue to push ALS research forward for everyone with ALS! https://t.co/gZtLJKQZk9 #EndALS #ALSAwareness

[Cortexa Therapeutics @CortexaTx]

Why We’re Betting on Calcium 🥛
We believe calcium dysregulation—not protein clumps—is the true engine of ALS progression.

🧠 Our approach targets the downstream chaos: calcium overload, mitochondrial failure, and energy collapse.

Take a deeper dive: https://t.co/gpui0zYJkd

[Cortexa Therapeutics @CortexaTx]

Growing Pains = Growing Progress 🚀
✅ Filing our provisional patent
✅ Secured the very 1st ALSRP DOD grant application
✅ Moving from scrappy startup to full C-Corp — because you can't run a biotech on caffeine, conviction, and a glorified Venmo forever.
We're building fast!💥

[Cortexa Therapeutics @CortexaTx]

Welcome to @CortexaTx💥 We’re here to disrupt the status quo in #ALS research—with bold science, radical hope, and an unshakable community.
🧠 ALS breakthroughs
🔬 Nate's journey
🤝 Join us
We’re not waiting for the future of ALS treatment—we’re building it. Be part of it!

[Cortexa Therapeutics @CortexaTx]

We’re moving fast 💥 We’ve officially selected our medicinal chemist! He brings deep CNS drug design experience + fresh insights to the team.
Meanwhile, we’re diving into strategy sessions to align the science with a sharp business plan. 🧩 Every piece matters—stay tuned!

[Cortexa Therapeutics @CortexaTx]

ALS isn’t just about motor neurons dying.
It’s about why they die.
We think we’ve found a new reason.
🔬 Learn more: https://t.co/SBuB8vW6sX
#BiotechStartups #Neuroscience #ALS #Cortexa #BrainResearch

[Cortexa Therapeutics @CortexaTx]

🥛 What if calcium isn’t just a player in neurodegeneration… but the key?🔑At Cortexa, we’re targeting calcium dysregulation to stop ALS before it’s irreversible. 🧠⚡️It’s early, bold, and high risk—but the upside could change everything.🚀Trials coming🔜 https://t.co/1FW9qR3XjT

[Cortexa Therapeutics @CortexaTx]

🧠 Neurodegeneration isn’t just complex — it’s solvable. At Cortexa, we’re targeting root causes like calcium dysregulation to rewrite the story of ALS and beyond. ⚡️From hypothesis to clinic — fast. 🚀
The future of neuromedicine starts now. 🔬
#ALSResearch #BiotechInnovation

[Cortexa Therapeutics @CortexaTx]

Hi, I’m Nathan Cole—Marine aviator, husband, dad, and founder of @CortexaTx. Diagnosed with ALS at 31, I’m fighting back by targeting the root causes of neurodegeneration. We’re moving fast—because people like me can’t wait. Learn more: https://t.co/y3plfFhqo5 #ALSResearch