So excited that it's finally out! Congrats 🎉🎉 @EleMargheritis for your great work and all our fantastic collaborators!!!
Gasdermin D cysteine residues synergistically control its palmitoylation-mediated membrane targeting and assembly | The EMBO Journal https://t.co/b87Gfg7rXq
First visualization of super-resolved GSDMD pores at the plasma membrane of pyroptotic cells!!! Fantastic work by Shirin @viten_skap and great collaboration with
@PiehlerLab iBiOs Osnabrück and @HummerLab
Check our preprint!
https://t.co/ixW7Se5JAT
I am amazed by the number of Italians I encountered at #EBSA2023 who are now living abroad. I have a mix of emotions here. I am sad that my homeland is emptying of outstanding scientists, but I am also proud of their courage in pursuing their dreams and embracing new journeys.
Looking for a great conference to end up 2023? Check out our Innate Sensing and Signalling in Immunology meeting (14-15 December 2023, Boston, USA)
https://t.co/Vzfh9lJdex
Organised by myself, @ClareBryant13 , @JelenaLab , @Rebecca_Coll and @abcam !
This is pretty incredible. Now, there is a druggable target to delay cell death -or at least, membrane rupture.
Potentially useful in settings in which caspase inhibitors did not work, from hepatitis (this paper) to stroke
👏@dixitvishva and team
https://t.co/8RBOtG6vh9
There is only a thin line (of lipids) between life🌻and death💀 In this review @HolthuisL, @Cosentino_Lab and I discuss the delicate balance between membrane damage & repair in the context of bacterial infections & the activation of cell death pathways. https://t.co/IINjxTg86X
Interested to work with a crowd of crazy scientists and support us in admin matters? We hire at the Biocenter, Medical University of Innsbruck. Full time. MS Office, English & German language required. @CeMM_News, @imed_tweets [email protected] for more info, please RT
#EWCD abstract submission is now open (deadline Feb 3rd, 2023)!!!
A great meeting for early career scientists to discuss their latest research in programmed cell death, lysosomal cell death, autophagy, immunology and cancer stem cells. All details at https://t.co/qlIlPZc6g4
Tremendous success: Biologists from Osnabrück University achieve funding by @dfg_public for Collaborative Research Center "Functional Plasticity Encoded by Cellular Membrane Networks". "We're delighted," said President Menzel-Riedl & Minister @FalkoMohrs.
https://t.co/v4nvhO2BBP
So honored and humbled to be selected as one of the recipients of the 2022 William B Coley Award, with Judy Lieberman, Feng Shao and Vishva Dixit (@dixitvishva) for our work on the pore forming proteins gasdermins, https://t.co/b8isCcg2kn
On #IWD2022, a huge shout out to all those fabulously talented #WomenInSTEM out there, including (but not limited to) all the exceptional female trainees, colleagues, collaborators and supervisors I have worked with over the years! 🎉
The pyroptosis executioner gasdermin D (GSDMD) is a redox sensor. Our new study demonstrates that GSDMD is oxidized to potentiate its oligomerization and pore forming activities, with Cys192 playing a critical role in ROS responsiveness.
https://t.co/r1hxAIRJI8
So excited that it is finally out!!
@MolecularCell
The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation
https://t.co/x11hCB2IVt
Happy to announce that @BBAjournals have made the collection of articles on "Death Mechanisms in Cellular Homeostasis" freely accessible for the next 2 months! Feel free to explore and to RT to your network: https://t.co/cjxwZCW1He @EuroCalcium @Eric_Chevet @crismunozp @MitosRUs