KB

Crit Care PharmD. Florida born, Georgia Boy at heart. #Nole #Heat #PharmICU #TwitteRX 🤙🏾

[Jose Ramos Vivas @joseramosvivas]

¿Funciona el test nasal PCR de MRSA si ya empezamos el tratamiento con mupirocina? 🤔 Un nuevo estudio en Clinical Infectious Diseases nos da la respuesta. 🧵👇

1️⃣ El test de PCR nasal para MRSA (Staphylococcus aureus resistente a meticilina) es clave para decidir si quitar o no antibióticos potentes (como vancomicina) en pacientes de UCI. 🏥

2️⃣ Existía la duda: ¿si ya aplicamos pomada de mupirocina (descontaminación universal), el test pierde fiabilidad? 🧪 El estudio analizó a >1000 pacientes.

3️⃣ ✅ El Valor Predictivo Negativo (VPN) se mantiene excelente (>98%) si el test se hace en los primeros 7 días tras iniciar la mupirocina, y es, no inferior a hacerlo antes de empezar la descontaminación. Si el test da negativo, es MUY poco probable que el paciente tenga MRSA.

4️⃣ Después de 7 días, aunque el VPN sigue siendo alto, la sensibilidad cae y el test puede pasar por alto las pocas infecciones verdaderas de MRSA. La PCR detecta ADN aunque las bacterias ya no estén viables, y además la incidencia de MRSA baja con la descontaminación. Por eso su utilidad clínica es muy limitada más allá de una semana.

5️⃣ Este hallazgo refuerza los programas de Optimización de Antibióticos (Stewardship): podemos confiar en la PCR para suspender tratamientos innecesarios incluso tras iniciar la descontaminación… siempre que estemos dentro de los primeros 7 días. 💊🚫
#Medicina #UCI #Antibióticos #Infectología #SaludPública #MRSA #Microbiología #SeguridadPaciente #PCR
👇https://t.co/NRWoLClroo

[ACCPpostgrads @ACCPpostgrads]

Congratulations William “Will” Turner! The ACCPpostgrads community looks forward to supporting your pursuit of PGY1 pharmacy residency training at WVU Medicine.

@WestVirginiaU
#CongratsPostGrad #RxMatch2026

[KB @CritCareKB]

Nice to see this in print. Supports my practice, though I was surprised by the compliance difference between groups. Reassuring secondary symptomatic VTE was similar (though the study wasn’t powered for this). Would love more head-to-head investigator-led studies. #CardioTwitter

[Davide Capodanno @DFCapodanno]

Finally published: the COBRRA trial, the first randomized head-to-head comparison of major DOACs — something the companies would never have done themselves, as a direct confrontation goes beyond their commercial interests. This was driven by independent investigators. The results somewhat support the idea of apixaban being the “safer” DOAC. That said, the list of study limitations is long, and for me, labeling something as “safe” is not enough — after all, even placebo is “safe” when it comes to bleeding. https://t.co/eYehndGzvB

[Contagion @Contagion_Live]

#ICYMI Our latest @SIDPharm Bench to Bedside column is out! Authors discuss phage–antibiotic combinations that may benefit select patients with multidrug-resistant infections.
https://t.co/APj08KCoxG

[ACCP INFD PRN @accpinfdprn]

Have you had to dose antimicrobials in patients with obesity?

The review article shared is my go to resource. Add it to your files to help with future drug dosing. 🧠🧠🧠

https://t.co/YCkKNmaD53

[SCCM Clinical Pharmacy and Pharmacology Section @SCCM_CPP]

🚨 The CPP Congress Buddy Program is OPEN! 🚨

Headed to the Society of Critical Care Medicine Congress? #PharmICU
👀 First time attendee?
💡 Seasoned pro?

Either way, there’s a spot for you 👇

[American College of Cardiology @ACCinTouch]

The 🆕 ACC/AHA Guideline for the Evaluation & Management of Acute Pulmonary Embolism (PE) in Adults is a de novo document offering comprehensive, evidence��based recommendations for the evaluation, management & follow‑up of adults w/ acute PE.

Read more: https://t.co/koqYhnZVIz

[SCCM Clinical Pharmacy and Pharmacology Section @SCCM_CPP]

🌟 Calling all CPP members! 🌟
The CPP Membership Committee's Congress Buddy Program is here to help you make the most of SCCM Congress! 🤝 Curious about the program? Check out this quick feature from one of our matched pairs!
#SCCM2025 #CPP #SCCM #PharmICU #Mentorship

[Los Angeles Rams @RamsNFL]

Day 2 of 12 Days of #ProBowlVote Giveaways!

🔁 Repost to win a signed @JaredVerse1 jersey!

[Mayo Clinic Infectious Diseases @MayoClinicINFD]

#ScholarlySunday features Dr. MJ Kim and her work on antimicrobial dosing in adults on ECMO. Congratulations MJ and to your collaborators and mentorship team! @IDDocAdi

[KB @CritCareKB]

@erin_barreto @PharmacyToDose Yep, we are in business! Thank you again

[KB @CritCareKB]

@PharmacyToDose @erin_barreto Not just you. Appreciate the effort and hopefully we still get access.

[SCCM Clinical Pharmacy and Pharmacology Section @SCCM_CPP]

Fresh out of residency and looking to establish your new practice? Join the CPP Mentor-Mentee Program to be connected with experienced pharmacists to help guide your career path! For more information, see Connect! https://t.co/sTYlv3aYoY
#PharmICU #SCCM

[SCCM SE Region @SCCMSE]

Chapter members: check out your inboxes for our latest newsletter! We have lots going on these days!

👉Ultrasound Course Sept 19
👉@SummitCritCare Sept 20
👉Stomp Out Sepsis 5k Oct 5
👉@BiteSizeMedEd on ECMO in Respiratory Failure Oct 23

Comment below if you’d like more info!

[KB @CritCareKB]

@JohnAllenPharmD @purduepharmacy Congrats Sir! Purdue is in great hands!!

[KB @CritCareKB]

@IM_Crit_ Next question. How much albumin did they give?

[SCCM SE Region @SCCMSE]

Hear more about the medical care being given in #Ukraine from Marina Rabinovich, PharmD, BCPS, FCCM & Barbara A. McLean, MN, RN, CCNS-BC, NP-BC, CCRN, FCCM in our next @BiteSizeMedEd on July 10th

Register here: https://t.co/lh55kJPl6o

[SCCM Clinical Pharmacy and Pharmacology Section @SCCM_CPP]

📢 Calling @SCCM_CPP members!
Enhance your research w/ our peer review service. Get journal selection recs, peer reviews & more. If you are interested in submitting a manuscript to the Peer Pre-Review Service, message @PayalKGurnani or @EstevesAly! #CriticalCare #PharmICU

[ACCP INFD PRN @accpinfdprn]

Happy Match Day 2024! Good luck to all!
#RxMatchDay

[AT @primediscussion]

@KirkHerbstreit If UGA and Oregon are better, why are they ranked behind FSU? Is FSU ranked 5th because they’re “5th best” or because it’s what they “deserve” based on their accomplishment and record? Is this an admission that the ranking logic and rules aren’t actually logical and consistent?