7a. STRASS-2 is a Randomized Phase III of Neoadjuvant Chemotherapy followed by Surgery versus Surgery Alone for Patients with High-Risk RPS @alegronchi
Link article: https://t.co/01x7uIyegk
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18s wrapped up Nationals prep today. 1st game tomorrow in Pittsburgh at 515 vs Anaheim. Thank you to our sponsor @FroJr18 for supporting the team this year #rollstorm
Our partnership with @DGlaucomflecken continues as he summarizes the final, 10-year outcomes of the CheckMate 067 trial, which investigated nivolumab plus ipilimumab in advanced melanoma. Access the article for free: https://t.co/phAdGwN6zj
@AnnSurgOncol@JamesHoweV Acknowledging itโs an uncommon manifestation, but has there been any experience with peritoneal metastases of NET? Does response to PRRT differ for those with peritoneal disease? Any role for debulking prior to PRRT? #ASOchat
@JamesHoweV@DrSabha@AnnSurgOncol How do you manage pts with intraoperative findings of small volume liver disease that did not show up on preoperative imaging ?
โYes, both SBNET and PNET patients had statistically significant improvements in PFS with PRRT, and OS was very close in SBNET patients (P=0.06). Smaller numbers may have contributed.โ - Dr. Howe (@JamesHoweV)
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@AMVillanoMD@AnnSurgOncol Retrospective data from the Netherlands also intriguing. Downstaging following PRRT is clearly possible, even at the tumor - vessel interface.
@AMVillanoMD@AnnSurgOncol Paging @spartelli, my go-to expert on the subject. He led the NEOLUPANET phase 2 trial. Preoperative PRRT certainly safe and can be done but will it improve overall outcomes as well as resectability? With the ORR seen, certainly something to think about