LauraCutugno

PhD in Microbiology (she/her).

Citizen of the world. Particularly fascinated by the microscopic inhabitants of this planet 🌍🦠

[LauraCutugno @CutugnoLaura]

Just created a new twitter account, for technical issues my old one (@LauraCutugno ) won't be active anymore.

[CBGP @CBGP_Madrid]

#ResearchCBGP | Unlocking Nitrogen Fixation for Crop

🇪🇸 - https://t.co/ClUKwTqGry
🇬🇧 - https://t.co/R5fKlfPBim

#somosUPM

[LauraCutugno @CutugnoLaura]

@PaoloDess1 @LEQUIA_UdG @AgrariaUnina Congrats, Prof. Paolo!

[Manuel González-Guerrero @manuelgg1977.bsky.social @manuelgg1977]

Congratulations to Cristina for her first first-author publication. Thanks to @EscuderoWelsch, @imperialj, and @Hendrik_Kuepper for their help in this work where we study a nodule-specific Cu-chaperone and identify new candidate Cu-proteins: https://t.co/L82hSj6NME

[LauraCutugno @CutugnoLaura]

@liuyuchen94 Big congrats, Dr! Well deserved!

[LauraCutugno @CutugnoLaura]

Last piece of my PhD story is finally out! Thanks to all my collaborators and to my PI, Dr Aoife Boyd @Aoife_B1!

[Pathogenic Mechanisms Research Group - Boyd lab @Aoife_B1]

Dr @CutugnoLaura of University of Galway @uniofgalway Molecular Pathogensis Research Group @Aoife_B1 characterises a rifampicin resistant #Vibrio vulnificus with increased sensitivity to hypoosmolarity and enhanced cytotoxicity. https://t.co/MDJ541jltV

[LauraCutugno @CutugnoLaura]

Come work with us!

[Angel Goñi-Moreno @angelgm.bsky.social @AngelGMoreno]

📢2yr postdoc position #postdocjobs. We are looking for a theoretician (CS, physics, maths) to join our EMMA project at the @CBGP_Madrid. Model and simulate microbes under #evolution and microbe-plant interactions. #synbio #genecircuits. Let me know if you are interested!

[LauraCutugno @CutugnoLaura]

❤️

[Quirinale @Quirinale]

#Mattarella:Nello studio dell’appartamento dove vivo ho collocato un disegno che raffigura un ragazzino, di quattordici anni, annegato, con centinaia di altre persone nel Mediterraneo. Recuperato il suo corpo si è visto che, nella fodera della giacca, aveva cucita la sua pagella

[LauraCutugno @CutugnoLaura]

Happy to share this other piece from my PhD work!
One further step towards the understanding of the role of the stressosome in V. vulnificus.
Thanks to everyone involved and in particular to my supervisor @Aoife_B1 😊

[Pathogenic Mechanisms Research Group - Boyd lab @Aoife_B1]

New research by @CutugnoLaura published today @MicrobioSoc. This paper completes Laura's PhD studies of the characterisation of the Vibrio stressosome.🦠😀 @cpobyrne @IrishResearch @MSCActions @Galway_Research @SYNMIKRO https://t.co/ALYz3GsZFO

[Veera Rajagopal  @doctorveera]

A mind-blowing paper has come out today in @Nature

In 2016, JC Venter Institute scientists trimmed a bacterial genome to its barest minimum required for life to synthesize what they called a "minimal genome" (https://t.co/Rk8oZJ0bUj).

Today, a group of scientists from Indiana University reports how that minimal genome evolved over 2000 generations in comparison to the non-minimal genome.

The authors found that even when you reduce a bacterial genome to its absolute minimum where every nucleotide matters, the genome undergoes mutational events generation after generation as much as the non-minimal genome. One simply cannot stop the evolution.

Just over 300 days of evolution (equivalent to 40,000 years in humans) the minimal cell has gained everything it lacked in fitness on day one in comparison to the non-minimal cell.

When comparing the evolved traits between the minimal and non-minimal cells, the scientists found something striking. The evolutionary process increased the cell size of non-minimal cells but not that of the minimal cell. But that is not the striking part.

The scientists were able to identify the key mutation that resulted in cell size evolution. And it turned out that the mutation that helped the non-minimal cells to grow bigger is the same that helped the minimal cells to stay smaller. Growing bigger had a survival advantage for non-minimal cells and not growing bigger had a survival advantage for minimal cells. So, the mutation had a context-dependent effect. This just demonstrates that the evolutionary effects on traits have no absolute direction. All that matter is what is beneficial for the organism's survival.

The conclusion of the paper is metaphorically a quote from the Jurassic Park movie:

“Listen, if there’s one thing the history of evolution has taught us is that life will not be contained. Life breaks free. It expands to new territories, and it crashes through barriers painfully, maybe even dangerously, but . . . life finds a way". (https://t.co/UlxRlb86CT)

https://t.co/zA9OAqSoAu

[LauraCutugno @CutugnoLaura]

@peoplepubit All'estero consegnate? Grazie 😊

[Oded Rechavi @OdedRechavi]

I saw the best minds of my generation fail to connect to eduroam

[LauraCutugno @CutugnoLaura]

@vdlorenzo_CNB @SEVAplasmids An incredible useful tool. Thank you for your work!

[LauraCutugno @CutugnoLaura]

Another piece of my PhD is out! Thanks to everyone that has collaborated to this! @cpobyrne @ietsbio3 and Jan Pané-Farré. Special thanks to my PhD supervisor @Aoife_B1.

[Pathogenic Mechanisms Research Group - Boyd lab @Aoife_B1]

Our publication on role of #Vibrio #stressosome in regulating glucose metabolism and motility.🦠@PATHSENSE2017 Research of @CutugnoLaura PhD studies @uniofgalway with Jan Pane-Farre @SYNMIKRO @cpobyrne @ietsbio3. Funded by @MSCActions @IrishResearch https://t.co/je8L4TQxE1

[CBGP @CBGP_Madrid]

👩🏽‍🔬 Feliz #DiaInternacionalDeLaMujer a todas las investigadoras 💜

[LauraCutugno @CutugnoLaura]

@msz11x Happy 8th of March!

[LauraCutugno @CutugnoLaura]

@sgizzi89 Lo fa per lavoro e le sfugge la differenza abissale tra le due cose?

Guardi facciamo finta di non esserci mai parlati. Non ho alcun interesse a continuare questo scambio.

Lei torni pure alla sua esperta vita, io torno alle mie inutili ricerche Google.

[LauraCutugno @CutugnoLaura]

@sgizzi89 Sarebbe bello sapere come lei sa tutte queste cose, invece. È soprattutto cosa sa.

Lei è sia un italiano all'estero che uno straniero in Italia? O ha solo letto i siti web di vari governi? Perché se no non capisco perché io dovrei tacere e lei può parlare?

[LauraCutugno @CutugnoLaura]

@sgizzi89 Parlo per sentito dire? Come pensa che ci sono entrata in diversi paesi? Di nascosto?

Se lei ritiene che fare richiesta di visto o dover compilare moduli o anche dover fornire prova di fondi economici/lavoro equivalga a giocarsi la vita, non abbiamo molto di cui discutere.

[Erri De Luca @Erriders]

Il ministro degli interni nega il dovere di soccorso in mare e il diritto di chiedere asilo. Poi dice di sapere cos’è la disperazione. È vero, l’ha procurata.