Olson Lab

We develop plasticity-promoting neurotherapeutics through a combination of chemistry, molecular/cellular biology, and behavioral neuropharmacology.

[Olson Lab @DEOlsonLab]

Check out our latest paper in Nature Neuroscience (https://t.co/jOC4Ik9DMz). This was a great collaboration with some very surprising results! Seems a glutamate burst & proximate IEG expression might not be necessary for structural plasticity induced by 5-HT2A partial agonists.

[Olson Lab @DEOlsonLab]

I love all of our papers equally, but I might love this one a bit more. Rare to see complex molecule total synthesis, molecular neuroscience, and behavioral neuropharmacology in the same paper! Thanks to everyone who helped make this work possible
https://t.co/iMByIkQHNU

[Olson Lab @DEOlsonLab]

follow us on Bluesky!

@deolsonlab.bsky.social

[Olson Lab @DEOlsonLab]

Check out our ibogaine total synthesis in @NatureChemistry! This was a tough project that took nearly a decade to complete by @UCDavisIPN researchers. Includes the synthesis of the unnatural enantiomer of ibogaine and ibogaine analogues that modulate SERT

https://t.co/2L7hI1Zmdj

[Institute for Psychedelics and Neurotherapeutics @UCDavisIPN]

Exciting new research in @ScienceMagazine
from the labs of IPN researchers @tinakim_neuro @DEOlsonLab reveals that the neural circuitry mediating the anti-anxiety and hallucinogenic effects of #psychedelics are distinct.
@UCDavisCNS
@UCDLandS
@UCDavisMed
https://t.co/HFgFTdJ6y4

[Olson Lab @DEOlsonLab]

Check out our latest collaboration in @ScienceMagazine Magazine with @tinakim_neuro's lab, where we re-activate psychedelic-responsive neurons to induce an anxiolytic effect without a head-twitch response.

https://t.co/gBbttZfuub

[UC Davis Department of Chemistry @UCDChem]

Exciting news! We've launched a crowdfunding campaign for a new art installation in the Chemistry Building! 🎨

Help us raise $5,000 for the amazing artists! Every contribution and share counts. Let’s create something extraordinary! 🙌💙

Join us: https://t.co/4RvjTVx5A5

[Institute for Psychedelics and Neurotherapeutics @UCDavisIPN]

IPN faculty affiliate @tinakim_neuro and team just published in @naturemethods about a protein-based tool expected to aid in identifying how #psychedelics impact brain disorders by tagging neurons activated by psychedelics. https://t.co/KJUYUJ6Fz3

[Olson Lab @DEOlsonLab]

Check out our latest collaboration with Christina Kim's Lab in Nature Methods:

https://t.co/M1B85WaGuq

The number of neurons tagged with CaST in the PFC following psilocybin administration correlated with head-twitch response, but the number of cfos tagged neurons did not.

[Institute for Psychedelics and Neurotherapeutics @UCDavisIPN]

The newest research from IPN Director @DEOlsonLab and team suggests that tropane analogs can promote #neuroplasticity with fewer side effects than compounds like scopolamine. Read more here: https://t.co/zBN63RJy3L

[Institute for Psychedelics and Neurotherapeutics @UCDavisIPN]

Check out the latest IPN paper in J. Med. Chem. on the development of psychoplastogenic DYRK1A inhibitors with potential for treating Alzheimer's disease especially early-onset Alzheimer's disease associated with Down Syndrome

https://t.co/Geiu3PTDWR.

[Institute for Psychedelics and Neurotherapeutics @UCDavisIPN]

@UCDavisIPN Director @DEOlsonLab talks about psychedelics and nonhallucinogenic psychoplastogens on the @UChicago's Big Brains podcast

https://t.co/KtEyUAMVgG

[Olson Lab @DEOlsonLab]

@cenmag article on ACS President @Mary_K_Carroll. She was one of my favorite professors when I attended @UnionCollege!

https://t.co/kjn5BUilPc

[Institute for Psychedelics and Neurotherapeutics @UCDavisIPN]

IPN director @DEOlsonLab was interviewed for this PNAS news feature on the mechanisms of psychedelics

https://t.co/idb8he3tXV

[Institute for Psychedelics and Neurotherapeutics @UCDavisIPN]

Within #psychedelic science, the debate lingers: Is it mind-blowing experiences or powerful #molecules that spur change? Join @TTBOOK to hear David E. Olson's take. Also available on @Spotify!

https://t.co/DEuOI3wcfl

[Olson Lab @DEOlsonLab]

The @UCDavisIPN will be sending out their first newsletter soon. If you are interested in #psychedelics or #neurotherapeutics and would like to receive a copy, please sign up by clicking on the link on this page:

https://t.co/b7b1sWJ6lB

[Olson Lab @DEOlsonLab]

Congrats to the Delix team on their positive phase 1 results that they are presenting at ACNP! Also, super excited that Jeff Jonas, former CEO/CIO of Sage Therapeutics, will be joining the Delix SAB!

https://t.co/g9jYzW4hOn

[Olson Lab @DEOlsonLab]

nice article featuring @UCDavisIPN associate director @johnalangray

https://t.co/TEYSEviQKw

[Olson Lab @DEOlsonLab]

article in @TheAtlantic on nonhallucinogenic psychoplastogens:

https://t.co/18giTQsUEJ

[Olson Lab @DEOlsonLab]

our latest review covering the effects of psychedelics on neuronal physiology:

https://t.co/Mv1cjtiUVo