Deborah Palazzotti

PhD student in Pharmaceutical Sciences at the I2DLab (In silico Drug Discovery Laboratory), University of Perugia. Computer-aided drug discovery (CADD)

[Deborah Palazzotti @DPalazzotti]

Hello everyone!
I’m a PhD student in Pharmaceutical Sciences at #UNIPG. I would be happy to discuss with you my research work on the kinase field. Enjoy poster 43 at the #PEVM2021.
@Net4Science
#MachineLearning #MedChem #kinase #inhibitors.

[Deborah Palazzotti @DPalazzotti]

I’m so honored to have received the runner-up prize for my PhD Thesis during the SCI Umbria-Christmas Lectures! Thanks to the @sci_umbria board for this award 🏅

Special thanks to my supervisors @letizia_barreca and @AndreaAstolfi_ for backing me up throughout my PhD journey!

[Andrea Astolfi @AndreaAstolfi_]

Do you need to build your own well-annotated chemogenomic dataset for a specific
protein target? Our #workflow Q-raKtion fits the bill!
Full article: https://t.co/yyCWTOkLaI
@DPalazzotti @letizia_barreca @JCIM_JCTC @KIME #chemoinformatics #datacleaning #compchem #machinelearning

[Deborah Palazzotti @DPalazzotti]

Do not miss our @AndreaAstolfi_ @letizia_barreca article on the rational identification of novel inhibitors of AKT1 for Acute Myeloid Leukemia (AML), a rare blood cancer. #RareDisease #Cancer #drugdiscovery #MolecularModeling

@MDPIOpenAccess

https://t.co/B8eTCRphfT

[Deborah Palazzotti @DPalazzotti]

Amazing experience!! 🦠🧬💻💊

[Erika Primavera @erikaprimavera_]

My first @sharpernight event. We shared our activities with high schools in the event "IL COMPUTER E LA SCOPERTA DI FARMACI ANTITUMORALI".
With @letizia_barreca @DPalazzotti at Dep. of Pharmaceutical Sciences @UniperugiaNews
#sharpernight #sharper2022 #unipg #perugia #ERN2022

[Maria Letizia Barreca @letizia_barreca]

@_AndreAstolfi_ from @UniperugiaNews presented our work on non-conventional small molecule degraders at #NMMC27 organized at Bari by @DCFSCI @SibyllaBiotech @prionicus @Giovann01476075

[Associazione Italiana Cristallografia @AICryst]

#aics2022
Innovative spalle molecole degraders affecting protein folding
Andrea Astolfi

[Associazione Italiana Cristallografia @AICryst]

#aics2022
Principles and applications of ligand- and structure-based drug design
Maria Letizia Barreca

[Deborah Palazzotti @DPalazzotti]

Glad to have shared my poster about the identification of novel AKT1 inhibitors for Acute Myeloid Leukemia at the #EFMCISMC2022

Special thanks to my PhD supervisors @letizia_barreca and @_AndreAstolfi_

@EuroMedChem @UniperugiaNews

[Deborah Palazzotti @DPalazzotti]

📌We're waiting for you at @sharpernight !!!
@UniperugiaNews
@letizia_barreca @_AndreAstolfi_

https://t.co/oj89u2abVH

[Deborah Palazzotti @DPalazzotti]

Amazing job @Andrea31463874!! 👏👏 @UniperugiaNews @letizia_barreca

[Università degli Studi di Perugia @UniperugiaNews]

🔬Ricerca per il contrasto dei tumori solidi presso il Dipartimento di Scienze Farmaceutiche #Unipg finanziata dalla Fondazione Veronesi👍
https://t.co/DKSouLjmcn

[Deborah Palazzotti @DPalazzotti]

Corrigendum:
Please find here the correct structure of T162

[Deborah Palazzotti @DPalazzotti]

P48: Small-molecule inhibitors targeting AKT1 active and allosteric sites.
@DCFSCI #IYMCVMEET #computational #cancer

[Deborah Palazzotti @DPalazzotti]

Dysregulation of AKT1 activity is one of the key factors for the development and/or progression of #cancer. Thanks to @DCFSCI for this opportunity! Enjoy the poster (P48) and don't hesitate to contact me for any information.

[Maicol Bissaro @_Maicol_]

As recently highlighted by @covid_moonshot @foldingathome, the combination of FBDD approaches with molecular simulations can revolutionize the drug discovery pipeline. I am therefore happy to share with you our review, which collects some of the latest metodological progres [1]