Dr.xvi79

🇫🇷 living in 🇧🇪. Chemist. dad of 2 little boys. good science please. I swear I will tweet more funny things when people consider Covid more seriously

[Dr.xvi79 @DXvi79]

@Gab_H_R It is THE metric, it has already dropped due to people dying (younger than they should have) during the acute phase.. But when people will realise it keeps dropping despite big wave of infection and death being over, it will remind us how the world was wrong to take Covid lightly

[Dr.xvi79 @DXvi79]

@_CatintheHat @SallyBourliakas @AlanLevinovitz https://t.co/t9DPJhZfBd

[The Vertlartnic @TheVertlartnic]

250 Symptoms? There’s No Way Long Covid Could Cause All That Unless It Affected The Entire Body And How On Earth Could It Do That?

[tern @1goodtern]

Ok.
I've read "The Painful Truth About Long Covid" six times through, and I'm ready.

Here are ten clues in the article that point to the writer's bad faith.

[Danielle Beckman @DaniBeckman]

Hey @WIRED, how about interviewing neuroscientists who are actually studying the brains of people with #LongCovid? I'm available, and so are many others in the field.

"When the brain gets stuck in a feedback loop of fight or flight" What does that even mean? #Pseudoscience

[Dr.xvi79 @DXvi79]

@manruipa @pan_accindex I indeed don’t think it is psychosomatic for the mouse 🐁 as well…. https://t.co/pr9wHYCh2h

[Putrino Lab @PutrinoLab]

Wonderful day for a new #LongCOVID paper! Thanks to an incredible collaboration with @VirusesImmunity and brilliant work done by @keylas3, we studied the effects of injecting antibodies taken from people with LC into mice compared with what happened

https://t.co/uotWM9LUEG

1/

[The Vertlartnic @TheVertlartnic]

Long Covid Estimate Revised Up After Researchers Include People With Long Covid

[Dr.xvi79 @DXvi79]

@TheVertlartnic @drstip https://t.co/cA0X2LrFxd

[Dr.xvi79 @DXvi79]

@roxiqt @LoriDTindall Especially doctors who kept telling to their friends, family and patients, that it is ok to catch Covid 3x per year, they will for sure not be the first one to make an effort to diagnose long Covid issue…

[Dr.xvi79 @DXvi79]

@GillesThoni @davidtuller1 Ça doit être psychosomatique pour les souris aussi alors qui se font injecter les anticorps de ceux attend de Covid long… https://t.co/my2061qvEp

[Bocquet Annelise 🔬🧬📚🚜 @AnneliseBocquet]

🧪 Enfin une étude qui montre noir sur blanc ce que beaucoup d’entre nous observons depuis longtemps.

Des chercheurs de Mount Sinai et Yale ont pris les anticorps de personnes atteintes de covid-long et les ont injectés à des souris saines. Résultat ? Les souris ont développé de la douleur chronique, de la fatigue et une inflammation des nerfs - exactement comme les patients.

Ce transfert ne s’est pas produit avec les anticorps de personnes guéries ou jamais infectées. Cela prouve que, chez une partie des malades, les symptômes (surtout les douleurs) sont causés par des auto-anticorps qui attaquent le propre corps : cerveau, nerfs, vaisseaux. Ce n’est pas psychosomatique. C’est biologique, réel, et transmissible par le sang.

C’est une avancée importante : elle valide l’auto-immunité comme mécanisme chez certains patients et ouvre la porte à des traitements ciblés (IVIG, plasmaphérèse, etc.).

Mais ce n’est que la partie visible.

Derrière ces auto-anticorps, il y a des mécanismes moléculaires à l’œuvre. La rupture de la tolérance au soi peut avoir diverses origines... inflammation chronique, problème dans l’ontogenèse des cellules immunitaires, programmation épigénétique (tiens… on risque de reparler de CXCL10), persistance antigénique ou du pathogène, terrains de prédisposition…

Ce qu’il faut bien comprendre, c'est qu'une fois la réaction auto-immune générée, on n’en guérit pas vraiment. On peut juste la contrôler. Et la moindre réexposition à l’antigène responsable, notamment la protéine Spike persistante, qu’elle vienne du virus ou des injections, risque de relancer la réponse pathologique.

Cela soulève aussi une question sérieuse pour les transfusions sanguines. Si les auto-anticorps et/ou la Spike circulante peuvent être transmis via le plasma ou d’autres composants, alors des donneurs asymptomatiques (post-Covid ou post-injection) pourraient potentiellement transférer ces facteurs à des receveurs vulnérables. Ce risque théorique mérite une vraie évaluation et des mesures de précaution (tests de Spike circulante, dépistage des auto-anticorps chez les donneurs, etc.), plutôt que le silence actuel.

Merci de votre attention

[Cat in the Hat 🐈‍⬛ 🎩 🇬🇧 @_CatintheHat]

@JamesMelville Seriously? You’re still trying to blame lockdowns (which ended nearly 5 yrs ago) for the ongoing decline & loss of energy?

Can I suggest you dig a little deeper, @JamesMelville.

The clues are all around 🔎

If you’re still struggling to join the dots, this thread might help ⬇️

[Dr.xvi79 @DXvi79]

@GillesThoni 💯 https://t.co/u7hk3dlzlS

[The Vertlartnic @TheVertlartnic]

Hantavirus Exposure During Quarantine Doesn't Count, Say Officials

[tern @1goodtern]

England is now just a tiny further rise away from losing Low Incidence of TB status.

Remember:
In 2022, there were people who said that Covid couldn't be causing immune dysfunction, because TB levels were static.

LOOK AT THEM NOW.

[Zdenek Vrozina @ZdenekVrozina]

This may be one of the more important long COVID papers in a while.
A new study in Frontiers in Immunology suggests that COVID can trigger new-onset insulin resistance - and that this may drive abnormal NETosis in neutrophils months after infection🧵

[Dr.xvi79 @DXvi79]

@GillesThoni https://t.co/cA0X2LrFxd

[Dr.xvi79 @DXvi79]

@roxiqt @LoriDTindall Especially doctors who kept telling to their friends, family and patients, that it is ok to catch Covid 3x per year, they will for sure not be the first one to make an effort to diagnose long Covid issue…

[Cat in the Hat 🐈‍⬛ 🎩 🇬🇧 @_CatintheHat]

@1goodtern BLOOMBERG (Jun 2024):

“Yes. Everyone, Everywhere, Really Is Sick a Lot More Often.”

At least 13 communicable diseases, from the common cold to measles and TB, are surging past their pre-pandemic levels in many regions, and often by significant margins.

https://t.co/xAc4wt2pVT

[Dr.xvi79 @DXvi79]

@beansprouts_mom Absolutely 💯 https://t.co/qb3VL7zVnp

[Dr.xvi79 @DXvi79]

We are in 2023 and this is scary how little we know about long term consequences of viral infection in general …

[Britta Domke @DomkeBritta]

Ach, schau an. Die hohen krankheitsbedingten Fehlzeiten seit 2022 sind gar nicht auf die Einführung der E-Krankschreibung zurückzuführen, sagt das @DIW_Berlin. Sondern auf einen sprunghaften Anstieg der Atemwegserkrankungen. Wer hätte das ahnen können? 1/4
https://t.co/IBt7J0h1Of

[Prof. Jose-Luis Jimenez @jljcolorado]

@bmj_latest @WHO 4) At the time of the pandemic @WHO et al. had some historical reasons to be confused

As time goes, this is less and less tolerable

https://t.co/Mlz7SNEUF7

[Dr.xvi79 @DXvi79]

@AntoninAtger https://t.co/2HDTsjQtaB

[Chichi 🎿 @cfhinor]

Qui a fait ça??? 😂😂😂

[Dr.xvi79 @DXvi79]

@Nain_Portekoi https://t.co/2HDTsjQtaB

[Chichi 🎿 @cfhinor]

Qui a fait ça??? 😂😂😂

[tern @1goodtern]

'Prolonged Close Contact' is the new 'It's not airborne'.

[The Vertlartnic @TheVertlartnic]

Officials Mildly Positive About Progress Of Andes Hantavirus Spread