Daniel Jacobson

CompBio Research Associate at @EarlyCancerCam @Cambridge_Uni | Studying cancer's destructive lifestyle 🧬📊 | Contributor for @BioNewsUK

[Jamie Blundell @jrblundell]

In 1999, Tom Maniatis discovered something remarkable: neurons achieve self-avoidance via stochastic methylation of the protocadherin gene cluster.

We've just discovered this locus is an evolvable in-vivo barcode across the human tissues: https://t.co/DMyHA5TIS0 🧵

[Maria Secrier @mariasecrier]

How do tissues organise, adapt, or collapse? 🧬
We’re looking for a postdoc with strong quantitative skills to tackle these questions in a highly interdisciplinary project bridging spatial omics, ecology & mathematical modelling.
Apply 👉 https://t.co/CPpu4AVcg5
Please share.

[Eran Segal @segal_eran]

We are rebuilding 💪

https://t.co/PBGBFEDXde

[Rebecca Fitzgerald Lab @RFitzgerald_lab]

Just published in @TheLancet! We show that the capsule sponge improves Barrett's surveillance, helping prioritize high-risk patients for endoscopy & offering a more efficient, patient-friendly approach for low-risk individuals. https://t.co/Fs5vlq6yxT
#GITwitter #Earlydetection

[Cenk Celik @_cenk]

[Preprint alert]
We’re thrilled to introduce EnrichMap: a powerful method for spatial gene set enrichment. It’s spatially aware, biologically meaningful and built for the next generation of spatial transcriptomics. https://t.co/mqo7IWHz1f

[Bingxin Lu @lubingxin]

Are you interested in cancer genomics and cancer evolution? A 3-year postdoc position available
to join my MRC-funded project on #ChromosomalInstability #CancerPhylogenetics!
Please get in contact if you are interested.
Deadline 30 Apr 2025.
https://t.co/RHxcpEdXDu

[Ahsen U. @Sciencythoughts]

Happy to see this invited world view article published; My personal call for clinicians & researchers working in oncology to be more empathetic when it comes to presenting patient data which has life-changing implications for the individuals in question
@NatRevGastroHep

[Matthew A. Clarke @MatthewACl31706]

Excited to share our new preprint exploring the potential to personalise treatment for non-small cell lung cancer (NSCLC) using in silico modelling: https://t.co/vodY0HHiuF

[Hrvoje Misetic @hrvshrvs]

🎉 Excited to share that our paper, "Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of esophageal cancer," has been published in Nature Cancer! 🧬

Read more: https://t.co/S9OjKCz6nk

[Maria Secrier @mariasecrier]

Delighted to introduce our new spatial transcriptomics tool, SpottedPy, recently published @GenomeBiology, allowing the identification of tumour hotspots at different scales and the exploration of distances and overlap with tumour microenvironment niches: https://t.co/SY0G6DcmTm

[Rebecca Fitzgerald Lab @RFitzgerald_lab]

🎓PhD Opportunities in Early Cancer Detection!
Join us for a fully funded 3.5-year PhD starting Oct 2025
🌟Projects include modelling progression risks in Barrett's Oesophagus
🗓 Apply by 16 Feb 2025
#phdpositions #AcademicTwitter #CancerResearch

[Simone Zaccaria @ZaccaSimo]

🚨So proud to present the first study from our @CCG_UCL group together with @CharlesSwanton @NnennayaKanu and led by @ojlucas with key collaboration @Ward__Sophie and fundamental support @Rija_Zaidi_ @abi_bunkum & many others

Out in @NatureGenet 👇
https://t.co/cd7YkBBDxo

🧵👇

[Stephen John Sammut @stephensammut]

How does immune failure enable metastasis and evolution in breast cancer?

Join us for a computational #singlecell #PhD @ICR_London.

Learn more and apply: https://t.co/NQXsElanrG

#CancerResearch #Bioinformatics #AcademicTwitter

[Luis Zapata @LuisglsZ]

📢 Exciting PhD Opportunity! Join https://t.co/pZwirSSB15 to explore immune cell populations in healthy and premalignant breast tissues. Study how BRCA mutations shape the immune landscape and the impact of PARP inhibitors on mutational signatures. Apply>https://t.co/PcZWH9Lrs6

[Alex Frankell @AFrankell]

🚨 Interested in spending 4 years studying how tumours evolve and developing new diagnostic methods? Take a look at the Alliance for Cancer Early Detection (ACED) PhD studentships available in my lab @EarlyCancerCam @CRUKCamCentre: https://t.co/hjWRiIEqst Deadline 4th Nov!

[Jakob Nikolas Kather @jnkath]

Finally out in @NatureProtocols : our group's workflows for end to end computational pathology. Compatible with UNI and other foundation models. Led by @ElNahhasOSM from @katherlab
journal link: https://t.co/oa2HFvH4Kg
full text: https://t.co/8zKLRNAgjB

[Mercury Prize @MercuryPrize]

The winner of the 2024 Mercury Prize is...

@Englishteac_her - 'This Could Be Texas' 🏆⚡️

#MercuryPrize

[Jamie Blundell @jrblundell]

How do healthy tissues evolve to become cancerous? Delighted to share our latest research tracking the somatic evolution that occurs in the decades before AML. 👇Implications for early detection and early interception. https://t.co/aJCATXkDKx

[PET @PET_BioNews]

Routine whole genome sequencing can improve treatment options for children with cancer, according to a recent NHS trial.
Dr @DanH_Jacobson writes more about this study in BioNews: https://t.co/cisB9ycqJF

#cancer #childhoodcancer #genetics #genomics #DNA #wholegenomesequencing

[Liam Collins-Jones @LiamHywelCJ]

UK Science Comedy Festival is THIS SUNDAY at Camden's People Theatre! Come to see a whole evening-and-afternoon of silliness, science, nonsense, chaos and very funny people.

Plus me, talking about how much I actually love brains!🧠🧠🧠

Tickets here: https://t.co/UeuDhuC06Y