Dan Ryder

Founder & Managing Director at Bridge Informatics. I'm passionate about #informatics, #datainfrastructure, #biostatistics, #drugdiscovery, #bioinformatics.

[Dan Ryder @DanRyder3]

@bradloncar so wish I was there

[Dan Ryder @DanRyder3]

@michael_gilman Shaw Park…Winnipeg?

[Dan Ryder @DanRyder3]

@michael_gilman Somewhere in Canada?🤔

[Bridge Informatics @Bridge_Info_USA]

ICYMI: We delved into groundbreaking research that harnessed #AI deep learning models to decipher the intricate “enhancer codes” hidden within our DNA. These enhancer codes play a crucial role in controlling cell identity. Read more: https://t.co/BxoTbBor8I

[Dan Ryder @DanRyder3]

@michael_gilman Thanks for the reminder Michael, done ✅

[Bridge Informatics @Bridge_Info_USA]

ICYMI: A new computational tool, MERCI, has the potential to reshape oncological research and prognostic assessments: https://t.co/HMxDeZfDh6 #MitochondrialTransfer #CancerResearch #MERCIAlgorithm #LifeSciences

[Dan Ryder @DanRyder3]

This turned out to be a really fun conference!

[Bridge Informatics @Bridge_Info_USA]

We presented a poster at #BioITExpo last week on a single-cell RNA sequencing (scRNA-seq) analysis we performed. Click here to view the poster and see how we dissected transcriptional profiles of complex biological systems at a single cell level: https://t.co/5bWVx5UGzi

[Bridge Informatics @Bridge_Info_USA]

We presented a poster at #BioITExpo last week on a single-cell RNA sequencing (scRNA-seq) analysis we performed. Click here to view the poster and see how we dissected transcriptional profiles of complex biological systems at a single cell level: https://t.co/5bWVx5UGzi

[Bridge Informatics @Bridge_Info_USA]

We’re here at #BioIT2024 in Boston! Come visit us at poster # 8 where we’re presenting on how to move from raw sequencing data to fully annotated cell clusters using #singlecell #RNAseq #singlecell

[Keith Hornberger @KRHornberger]

Ribbon bling is a bit out of hand this year

[Bruce Booth @LifeSciVC]

Today we should celebrate the perseverance of $VRTX in translating the incredible human genetics of Nav 1.8 for pain into a drug with Phaase 3 data ready for approval. The commercial market can debate the differentiation and merits vs existing generics, but it should be a huge celebration for novel science and the value of the genetic validation of targets in drug discovery - which instills the confidence in expensive, long-term, multi-candidate R&D programs against these genetic targets.

[Dan Ryder @DanRyder3]

@zhangf Thanks @zhangf , it’s good to see molecules can “bridge the gap” the way we do it too! https://t.co/6Tp3l2j55Q

[Dan Ryder @DanRyder3]

@anissagardizy8 @aaronpholmes Thanks @anissagardizy8!

That move is bold, but we’re definitely happy to see it at BI - as are our customers!

[Jorge Conde @JorgeCondeBio]

Hospital in Spain offers home-brewed CAR-T cell therapy at 1/3 of commercial cost.

Hospitals can’t manufacture most medicines. But for CAR-T, patients’ own cells are removed + reprogrammed + returned to kill cancer.

“The process is the product”
🇪🇸 🧫
https://t.co/3BPtRrCtFn

[Dan Ryder @DanRyder3]

@JorgeCondeBio @jaybradner @Amgen Congrats @jaybradner this is exciting!

[Bridge Informatics @Bridge_Info_USA]

ICYMI: Can bacteria be living biosensors? Read about the remarkable approach of engineering bacteria to detect cancerous DNA in models of colorectal cancer in our blog: https://t.co/270zvN7VKm

[Bridge Informatics @Bridge_Info_USA]

As researchers continue to uncover connections between mind & body, they're better equipped to develop more effective treatment strategies. Today’s blog explores how stress management could enhance treatment success for IBD patients: https://t.co/2PhWKuZP2C

[Bridge Informatics @Bridge_Info_USA]

ICYMI: Have you read about the newest applications for uncovering the architecture of gene regulatory networks? Last month's blog explains what they are and how to use them: https://t.co/2jZUEz79Vk

#bioinformatics #bridgeinformatics

[Bridge Informatics @Bridge_Info_USA]

AAV-Perturb-seq allows researchers to peer into the intricate world of geneotype to phenotype correlations with unprecedented precision. Learn more in today’s blog: https://t.co/ik2kPSVUkS

[Bridge Informatics @Bridge_Info_USA]

ICYMI: How can CAR-T therapy be applied to new cancer types? In a recent paper, researchers analyzed RNA-Seq data for novel, safe targets to treat acute myeloid leukemia (AML). Read more on BI's blog: https://t.co/b3RUIw99y3