Daniel Podlesny

Research Scientist, EMBL Heidelberg,
@podlesny.bsky.social

[Daniel Podlesny @DanielPodlesny]

Excited to release https://t.co/Y0dqRieRhB! 🦠 Explore 140+ 𝗺𝗶𝗰𝗿𝗼𝗯𝗶𝗮𝗹 𝗽𝗵𝗲𝗻𝗼𝘁𝘆𝗽𝗶𝗰 𝘁𝗿𝗮𝗶𝘁𝘀, harmonized & integrated from culture-derived collections 🔬 & genome-based predictions 🧬 for >2M MAGs & genomes.

Paper at NAR: https://t.co/Dx7kjmA9uD 🧵 1/9

[Daniel Podlesny @DanielPodlesny]

full thread at https://t.co/bgckzN2WNV

[Daniel Podlesny @DanielPodlesny]

Excited to release https://t.co/Y0dqRieRhB! 🦠 Explore 140+ 𝗺𝗶𝗰𝗿𝗼𝗯𝗶𝗮𝗹 𝗽𝗵𝗲𝗻𝗼𝘁𝘆𝗽𝗶𝗰 𝘁𝗿𝗮𝗶𝘁𝘀, harmonized & integrated from culture-derived collections 🔬 & genome-based predictions 🧬 for >2M MAGs & genomes.

Paper at NAR: https://t.co/Dx7kjmA9uD 🧵 1/9

[Daniel Podlesny @DanielPodlesny]

This thread was originally posted on 🦋. It is partially broken here. Consider switching.

[Daniel Podlesny @DanielPodlesny]

@FrankRHutter is there a solution for wide data? pm

[Jens Walter @JensWalter15]

For somebody working on the gut #microbiome, the responses ("gross", "embarrassment", "pseudoscience", etc.) to this @Nature article on the treatment of C-section babies with their mother’s poo are quite sobering. So, I thought I would provide a perspective in the thread below.

[Andreas Klinger 🦾 @andreasklinger]

Sign for Europe: https://t.co/6C6P3oKP1k

[Daniel Podlesny @DanielPodlesny]

@vsbuffalo You can use webhooks on @SlackHQ

[Joshua Siegel @realJoshSiegel]

After a high dose of psilocybin, the brain desynchronizes at a massive scale, causing loss of our sense of self, time, and space. This may drive the burst of plasticity caused by psychedelics. The next day, brain activity has largely returned to normal, but an echo remains – a reset of circuits critical to the sense of self.

Our study is out today in @Nature https://t.co/PjACA6nkAy

[Dr. Nazgul Sakenova @SakenovaNazgul]

Thrilled to share our new preprint. A thread 🧵

https://t.co/dEwPbT9GNB

[Manolis Kellis @manoliskellis]

Immensely proud to share our four papers on #SingleCell dissection of #Alzheimers Disease coming out in @CellCellPress today, reporting 2.3M #scRNA profiles and 850k #scATAC profiles across 427 post-mortem human brain samples from AD and non-AD donors in a wonderful #interdisciplinary collaboration with @DrLiHueiTsai between @MIT @MIT_Picower @MIT_CSAIL @BroadInstitute @RushUniversity
Paper 1: scRNA + vulnerability + resilience https://t.co/I7cmizyj9C
Paper 2: scATAC + GWAS + Epigenome Erosion https://t.co/bdtlu9bWDr
Paper 3: Microglia States + reprogramming https://t.co/NzEJF1wY3t
Paper 4: DNA damage + gene fusions https://t.co/hIY1tMMhLo
MIT News: https://t.co/oLDuBBb45S
Issue: https://t.co/Mup3orjhcl
News & Views: https://t.co/xQk5mepDqz

[Big Data Biology Lab @BigDataBiology]

New preprint with @delafuenteupenn : The antimicrobial peptides (AMPs) of the global microbiome!

From 72 diffferent habitats (the best current sampling of the global microbiome) we obtained almost 1 million candidate AMPs

https://t.co/t8hRmjM4XZ

[Cameron Thrash @jcamthrash]

Greengenes2 unifies microbial data in a single reference tree https://t.co/6CS3SzoBMk

[Uri Alon @UriAlonWeizmann]

1/ 🤰What can we learn about pregnancy form 45 million lab tests? We present a dynamic atlas of pregnancy and postpartum based on measurements from over half a million pregnancies at a one-week resolution. @biorxivpreprint @AlonBar10

[Anders Sandberg @anderssandberg]

This is awesome (new genetic code acting as a bidirectional firewall for infection and gene transfer) and a bit frightening (potentially higher fitness): I am glad they added a proper biocontainment (stable dependency on non-standard amino acid). https://t.co/k9vg9WWKwI

[Noa Rappaport @nrappapo]

Our new @NatureMedicine study aims to improve our understanding of obesity & its impact on health. Although useful, classical BMI misclassifies ~30% of people. To capture the heterogeneity of obesity, we developed blood-omics-based biological BMI (bBMI). https://t.co/1epgOuPghI

[Christine Moissl-E @chmoei]

Necrotizing enterocolitis (#NEC) is a devastating disease, affecting up to 11% of all very-low birthweight (<1500g) infants.
In our newest paper @Naturecomms we look at NEC prophylaxis regimens in clinics that are highly successful in preventing NEC (average NEC rate: 2.9%).

[Joseph Tintelnot, MD @JosephTintelnot]

I am thrilled to share with you our recently published paper showing that the microbiota-derived metabolite 3-IAA influences chemotherapy efficacy in #PancreaticCancer @Nature
https://t.co/Qomu72u1jB

[Ethan Mollick @emollick]

Forget losing jobs to AI, look to the sky!

Flocks of pigeons detect cancer in scans with 99% accuracy & “are suitable surrogates for human observers in certain medical image perception studies, thus avoiding the need to recruit, pay & retain clinicians...”https://t.co/W7rWW31EPD