Siddharth

[Siddharth @DarthSidious07]

@DrRishabhOnco @OncoAlert Great post @DrRishabhOnco - very informative. I have a follow-up question - for Enhertu's approval in 1L HER2+ BC the label says HER2+ (IHC 3+ or ISH+) but for the Gastric Approval it calls out HER2+ (IHC3+ OR IHC2+/ISH+) - is IHC2+/ISH+ same as ISH+?

[Siddharth @DarthSidious07]

@poorni_manohar Do we have a registration number for this study? I tried searching for HERizon-Breast but didnt get any hits. this looks similar to the SAPPHO study -

[Siddharth @DarthSidious07]

@SidhiBaweja @TataMotors You should all come over to @HyundaiIndia side. 4 years after buying, my Aura runs like butter. Had 1 issue of petrol indicator not working, the company replaced the entire tank/ faulty unit in 2 days. Very very happy with their service

[Siddharth @DarthSidious07]

@CeoNoida @Noidatraffic @GreaterNoidaW @CMOfficeUP

1 hour long traffic jam for 1km.

Daily life of a noida wasi.

When will this problem get solved?

[Siddharth @DarthSidious07]

@ANI There should be a special Belt & Rod Initiative for these people. 0.5 is the perfect name cause that describes their IQ level! #PKMKBForever #ModiHaiTohMumkinHai

[Siddharth @DarthSidious07]

@sidhant @theskindoctor13 Why do I feel this is going to make life difficult for the TurkishIceCream man in the local mall?? Screw that, greek yoghurt is healthier anyway! #turkey #Greece #IndianArmy #Modi @MEABharat #PKMKBForever

[Sidhant Sibal @sidhant]

We will continue to stand by the brotherly people of Pakistan in good and bad times, says Turkish President Ergodan

[Siddharth @DarthSidious07]

@RShivshankar Politics should not be above the country. Every Q by idiots on the Op just shows how divided we are. More proof of 0.5 gang. Talking dung like this will get you votes? nope, its pushing people like me farther right. I think you shld learn a few things from the Pakis!
Jai Hind!

[Siddharth @DarthSidious07]

Thank you @AtishiAAP and ilk for reminding me why I am pro and proud of RW. if you cant digest India's progress i suggest you huddle up in each others houses and cry your eyeballs out. we are not interested @MoIB_Official they will cry freedom of speech but what they need is UAPA

[Megh Updates 🚨™ @MeghUpdates]

The internal enemies, SABOOT GANG and the Political Vultures questioning the Valour of our Forces and Govt action are Back!!

[Siddharth @DarthSidious07]

@airindia Thank you for confirming. It's very strange that we don't have a gold track for our national airlines at the national capital. Hoping to see one soon, would be great if @airindia and @DelhiAirport figure this out

[Siddharth @DarthSidious07]

@airindia quick question - does having a gold/ platinum status allow you to use the business security line at delhi airport? Curious b/c security says no but on united same star alliance status prints priority on boarding pass which is allowed to pass through business sec

[Siddharth @DarthSidious07]

5/ As precision oncology grows, so do the expectations for delivering meaningful outcomes through accelerated pathways.

What do you think of these trends? Let us know below!

#Oncology #GUCancer #CancerResearch #OncologyUpdates #PrecisionMedicine #FDAApprovals @Larvol

[Siddharth @DarthSidious07]

2/ 1️⃣ Accelerated Approvals Converted to Full Approvals:

Total conversions: 8
Average duration: 42 mos
Fastest conversion: 16 mos (Elahere 2L+ FRa+ pt-resistant OvCa)
Longest duration: 62 mos (Keytruda 2L+ HCC sorafenib pre-tx)
#FDA #CancerTherapies @NCCN #GynCancer #GICancer

[Siddharth @DarthSidious07]

4/ The evolving FDA approvals in 2024 underscores the importance of:
✅ Robust confirmatory trials for accelerated approvals.
❌ Adapting strategies for unmet needs in indications with high clinical trial complexity.
#FDAApprovals #CancerInnovation #asco #NCCN #ESMO #Oncology

[Siddharth @DarthSidious07]

FDA Approval Trends & Updates in 2024 🚨

1/ Key Updates on Accelerated Approvals in 2024
Here’s a breakdown of how the FDA’s approvals evolved this year
✅ Full Approvals: 8
❌ Withdrawals: 5

Let’s dive into the numbers!
#Oncology #FDAApprovals #PrecisionMedicine @FDAOncology

[Siddharth @DarthSidious07]

7/ Which trends or approvals stood out to you in 2024? Let us know in the comments!

#Oncology #ESMO #ASCO #CancerTherapies @FDAOncology @ASCO @myESMO @NCCN @lcsmchat @theNCI @Larvol

[Siddharth @DarthSidious07]

1/ Key Insights from 2024 FDA Approvals (Jan 1 - Dec 25) 🚀🔍
Here’s what you need to know about this year’s trends in oncology drug approvals.
#Oncology #FDAApprovals #PrecisionMedicine

[Siddharth @DarthSidious07]

6/ 4️⃣ Rise of pan-tumor approvals:

The precision oncology trend continues with 3 pan-tumor approvals:

AUGTYRO: For NTRK gene fusion-positive patients
Retevmo: For RET gene fusion-positive patients
Enhertu: For HER2 IHC3+ solid tumors
#PrecisionMedicine #BiomarkerTherapies