David Eisner

@TheBHF Professor of Cardiac Physiology @OfficialUoM. Editor-in-Chief @JGenPhysiol. I research calcium signalling in the heart. (All views my own).

[Journal of General Physiology @JGenPhysiol]

Dmytro Vasylyev, Sidharth Tyagi, Stephen G. Waxman et al. @YaleMed show that Nav1.7 and Nav1.8 #sodiumchannels work cooperatively to control sensory-neuron excitability. https://t.co/BBJfqR5Deu

#Biophysics #MolecularPhysiology #ComputationalBiology #Nerve #IonChannels

[David Eisner @DavidAEisner]

Beyond “non-significant” results: Why and how to test for practical equivalence | PNAS https://t.co/Mh40IdeFhK

[Journal of General Physiology @JGenPhysiol]

“I greatly admire the journal’s style and editorial policy, as well as the dedication and enthusiasm of its editors.”— Dr. Yasushi Okamura (@yasushiokamura1). JGP, where editorial decisions are based purely on research quality: https://t.co/qUlU0Hksm9

[Journal of General Physiology @JGenPhysiol]

New study by Burwood, Fridberger, et al. describes the distinctive mechanical response characteristics of the guinea pig apical cochlear organ of Corti and basilar membrane, neither of which is tonotopic in the apex. https://t.co/z2Nsp8LzAh

[Journal of General Physiology @JGenPhysiol]

.@lfsantana68 lab @ucd_physiology shows that beat-locked cytosolic and mitochondrial ATP transients in sinoatrial node myocytes sort into high-gain, low-gain, or consumption-dominant modes aligned with superior–inferior vascular–mitochondrial gradients. https://t.co/G3oushd030

[Journal of General Physiology @JGenPhysiol]

“We have chosen to submit our work to the Journal of General Physiology because we are confident that the review process will be fair.”— Dr. Daniel Fitzsimons. Learn how scientists set the course 👉 https://t.co/Uzlx3xaYfp

[David Eisner @DavidAEisner]

Godfrey Smith and I have written a commentary on this paper. Fascinating interactions between Mn2+ and Ca2+ with implications for Ca2+ handling. https://t.co/BpLF6ANivs

[Journal of General Physiology @JGenPhysiol]

Jaque-Fernandez et al. @UnivLyon1 show that depolarization of #zebrafish #SkeletalMuscle fibers evokes a Mn²⁺ quenching signal that does not result from store-operated Ca²⁺ entry but from a displacement of Mn²⁺ accumulated on intracellular Ca²⁺ buffers https://t.co/BhcygTYshq

[David Eisner @DavidAEisner]

@CactusFrankS @JustineBateman i was there!

[Journal of General Physiology @JGenPhysiol]

Yu Zhou, @LingleChris et al. ask whether distinct β subunit isoforms coassemble in BK channel complexes or segregate into different complexes. They show that ternary β2:β3:α complexes form, consistent with a trinomial model of random mixing of β subunits. https://t.co/dIbXHPfcsS

[David Eisner @DavidAEisner]

Delighted to receive copies of the (just published) book on statistics that @JakubTomek13 and I have written. Presents statistics and related experimental design without maths and jargon. Available from: https://t.co/Z9PFqOZx2n or https://t.co/H7HhFhL06V

[David Eisner @DavidAEisner]

@CactusFrankS Wonderful photos

[Society of General Physiologists @sgpweb]

Announcing the new SGP Rising Star Travel Awards for students and postdocs. The $500 awards can be used for meetings held up to 1 year from notification. Apply today! Deadline: 1 August 2025 https://t.co/Ha585KTLQn

[David Eisner @DavidAEisner]

@PavlovicDavor @ISHR_ES Davor, the ISHR is lucky to have you. I enjoyed the role enormously and hope you will too!

[Society of General Physiologists @sgpweb]

SGP is excited to invite proposals for thematic meetings for the years 2027 through 2029. These meetings will provide a platform for researchers to engage in meaningful discussions on critical topics within the field of physiology. Deadline: 1 June 2025 https://t.co/DWt1ClxjRv.

[David Eisner @DavidAEisner]

Great to publish in @JGenPhysiol

[Society of General Physiologists @sgpweb]

SGP congratulates Dr. Rachael Lucero on receiving the 2025 Cranefield Student Award for her outstanding paper, “Transport of metformin metabolites by guanidinium exporters of the small multidrug resistance family” https://t.co/e0gX7tSVmK

[David Eisner @DavidAEisner]

Great to publish in @JGenPhysiol

[Society of General Physiologists @sgpweb]

SGP congratulates Dr. Man Si on receiving the 2025 Cranefield Postdoctoral Fellow Award for her outstanding paper, “Epilepsy-associated Kv1.1 channel subunits regulate intrinsic cardiac pacemaking in mice” https://t.co/x3nyfXiSKZ

[David Eisner @DavidAEisner]

Great to publish this in @JGenPhysiol

[Society of General Physiologists @sgpweb]

SGP congratulates Dr. Huanghe Yang on receiving the 2025 Paul F. Cranefield Award for his outstanding paper, “Niclosamide potentiates TMEM16A and induces vasoconstriction” https://t.co/Z21VWvCk0B

[David Eisner @DavidAEisner]

@danmjohnson @Cardio_KULeuven @EefDries @macquaide @roderick_cardio @RachelterBekke @volderspaul A wonderful day celebrating some of the highlights if Karin’s career

[The Physiological Society @PhySoc]

@OfficialUoM @OFishialLab Read the full article in #PhysiologyNews: https://t.co/HzbIfwUWgE 🧵8/8

[David Eisner @DavidAEisner]

It was fun writing it.

[Journal of General Physiology @JGenPhysiol]

New Review: Elizabeth Murphy @nih_nhlbi and @DavidAEisner @OfficialUoM discuss the regulation of mitochondrial calcium and its role in regulating cell death. https://t.co/iTYoXYwML8

#CardiacMuscle #CellularPhysiology