David ｜Pharma × AI

Aseptic manufacturing veteran learning new tricks. 10 yrs CDMO Ops, now using Claude as my thinking partner

[Manchurius Hao — Greeks.live首席赌狗 @AntonLaVay]

我跟你们说，美股这玩意儿，就真的是特简单，你就找这最热门行业中的的股票中，远期期权OI疯狂增加，远期IV开始上扬，LEAPS被明显扫货的公司。

老登股什么玩意儿跟你说稳健的直接隐藏。

然后跟单就这么简单，美股讲究的就是一个跟单，倍儿地道。

一定要关注LEAPS，那些13F大佬建仓全是LEAPS，短期期权韭菜的噪音太大了。

我几乎可以肯定 $nok 当下正在被13F大佬疯狂建仓，因为如果我们看到一份13F，反推他们是什么时候建仓的也是看OI的，

记住，小成交量可以被刷成大成交量，但是大成交量不能被伪装成小成交量，难以隐藏自身，因为OI在增加，IV在上扬。

凡是接触，必留痕迹。

我应该是当时最早发现 $nok LEAPS在被疯狂建仓的。

[Aakash Gupta @aakashgupta]

68 college students played video games an hour a day for 30 weeks. They got measurably smarter. EEG brain scans confirmed it.

The setup was simple. Half the group played League of Legends, an action game. The other half played Legends of the Three Kingdoms, a strategy card game. Same hours, same schedule, no gaming experience for anyone going in. Both groups improved on attention, working memory, and executive function. The League group's gains were significantly larger in spatial attention and spatial working memory. The benefits were still measurable 10 weeks after the gaming stopped.

None of this is new.

Daphne Bavelier's lab at the University of Geneva has been replicating this finding since the early 2000s. Her 2018 meta-analysis in Psychological Bulletin pulled data from 8,970 participants across 15 years and found the same thing. Action games train attentional control, a brain skill that transfers to other tasks. Strategy games train deliberation, which mostly stays inside the strategy game.

The mechanism is the counterintuitive part. Action games train your brain by giving you no time to think. The brain can't deliberate. League of Legends throws 9 champions, hundreds of minions, dozens of abilities, mana, cooldowns, and map state at you, all updating in milliseconds. The brain learns to perceive faster instead. That perceptual speed transfers to anything else that demands the same skill.

Including surgery.

The 2007 Rosser study in Archives of Surgery found that laparoscopic surgeons who played video games more than 3 hours a week made 37% fewer errors, completed procedures 27% faster, and scored 42% higher on overall performance. The top third of gamers made 47% fewer errors. Laparoscopic surgery is a 2D screen with distorted depth perception, remote-controlled instruments, and multiple data streams updating in real time. The cognitive profile is almost identical to an action video game.

The 10-week persistence is the part that should change how this gets discussed. If the gains were just from practicing the game, they would have disappeared the moment the students stopped playing. They didn't. The 30 weeks rewired the perceptual system, and the rewiring stayed.

[Dan Go @CoachDanGo]

This 3 minute breakfast got me to 12% body fat

At 46, I got my abs back and this breakfast is the biggest reason why.

Here's what's in it and why it works:

[Tw93 @HiTw93]

周末在整一个新的 Skill 叫做 Kami (紙, かみ)，大伙可以把他当做 Waza (技, わざ) 的妹妹，Kaku(書く) 的女儿，主打用于 Paper 排版的场景。

比如说你需要产出一页纸的报告，你需要写一个白皮书、需要产出一个精致的PPT、需要弄一个作品集的 PDF 发给别人等等，也就是任何排版的打印场景都可以使用，自动生成精致PDF，里面还具备自动绘制清晰图的能力。

差不多快弄好了，晚上下班后继续整了整，慢慢舒服了，还需要做一点装修的事情，我非常喜欢简洁、清晰、美观的设计方案，但是不喜欢现在看着都是一样的 ai design 风格，所有就用周日一整天做了 Kami，用于我的创作类输出，也分享给小伙伴，期待这周来开源。

[Camus @newstart_2024]

Vitamin D just got a serious upgrade.

A new study found that taking 2,000 IU of vitamin D3 daily for four years significantly slowed telomere shortening — the biological countdown that accelerates aging and age-related diseases.

Researchers saw clearer protection in adults 50+ compared to placebo. Omega-3s didn’t show the same effect.

It’s not a miracle cure, but it adds real weight to vitamin D’s role in fighting inflammation and supporting healthier aging. Even short daily walks in daylight can help your body produce it naturally.

What’s your take — are you already supplementing with vitamin D, or does this make you want to start?

[陈成 @chenchengpro]

Claude Code 有个 5 小时重置机制，意味着你可以通过定时任务来卡重置节点，让每个工作时段都从满血状态开始。

设置只要三步：

1）打开 https://t.co/lfGbFsSmP2
2）选 Custom，输入 5 7,12,17,22 * * *
3）点 Create

这样每天 7:05、12:05、17:05、22:05 会自动触发一次对话，重置 5 小时倒计时。对应的就是上午、下午、傍晚、深夜四个时段，每段都能用满 token 额度。

关键是这个任务跑在云端，本地不用开电脑，比 crontab 优雅。

via @MinLiBuilds

[Thariq @trq212]

Managed Agents is the first 'agent in the cloud' API that has the right mix of simplicity and complexity.

Implementation details like how you manage a sandbox are abstracted, but you have a lot of control over the actual execution of the model.

[Innomad 一挪迈 @innomad_io]

这下好了，TradingView 都有 mcp 了😂

这哥们儿开源了一个项目，支持 Claude Code / OpenClaw 安装使用。

已实现：
- AI 技术分析，可以对比多个股票、Crypto 的各种技术指标
- AI 跑回测
- 情绪面分析
- 市场扫描
- 更多功能持续增加中...

行情数据直接对接了 Yahoo Finance 也不需要任何付费 API 了

看 Demo 视频挺酷炫的。等我 Claude Code token 重置了试试😂

链接放到评论了👇

[AlexZ 🦀 @blackanger]

生化危机女主米拉·乔沃维奇花了几个月的时间，与 Claude 一起创造了一款人工智能记忆系统。

跑分满分——击败了该领域所有同类产品，无论是免费的还是付费的。

https://t.co/mWm6pJPYoj

没想到我能在 GitHub 关注到这位女神。

[Anthropic @AnthropicAI]

Our run-rate revenue has surpassed $30 billion, up from $9 billion at the end of 2025, as demand for Claude continues to accelerate. This partnership gives us the compute to keep pace.

Read more: https://t.co/XgSjL0And7

[Bill The Investor @billtheinvestor]

Claw Code 火速刷新 GitHub 纪录！Anthropic 泄露 Claude Code 源码后，开源社区一天内用 Rust 重建，斩获 139K 星和 102K 次 fork，成为最快突破 10 万星的代码库。

这个过程显示，开发者协作速度和技术门槛已经大幅降低，开源力量正以惊人的效率推动行业前进。

[Bill The Investor @billtheinvestor]

这哥们把任何 repo 反向工程成原始 prompt 了。

[Andrew @Tradesdontlie]

Claude controlling @tradingview live — switching symbols, writing Pine Script, batch scanning futures, replay trading, drawing levels. All from the terminal. Still rough edges but the vision is clear.

[AYi @AYi_AInotes]

越熟练用 Claude Code，反而越容易花最多时间在返工上

很多人以为“prompt写得够清楚、context塞得够多”就能让Claude高效输出。结果呢？它还是直接开写、直接出bug、直接跑偏，最后你花80%的时间在来回纠错、澄清假设、推翻重来。

作者用 Claude Code 满一年，Superpowers（Jesse Vincent 开源，125k+ GitHub stars，每周涨1.5-2万）是唯一让他速度、质量、挫败感同时大幅改善的插件。

普通 Claude 直接“开始建”而不问问题、写计划，大部分时候都要花1小时 course-correct；Superpowers 强制模拟“好工程师”的真实流程（先探索上下文→逐一澄清问题→提出2-3种方案+权衡→分段写设计文档→自审→等待明确批准）。

14+ skills 按任务自动触发且 mandatory（跳过有12条开发者常用借口会被框架拒绝）；7阶段管道每阶段都有铁律（planning 里不允许 TBD/TODO、TDD 必须先写 failing test、debugging 3次失败就强制质疑架构）。

这些结构不是锦上添花，而是把 raw prompting 的天花板彻底打破，让 Claude 真正像团队里的资深工程师一样思考和执行。

对任何重度使用 Claude Code 的人来说，Superpowers 不是“又一个插件”，而是把 agentic workflow 从混乱拉到可预测、可维护、可规模化的分水岭。

[宇峒 @xYsfknBXPT6M0jo]

我真希望在我还是球员的时候就知道这个操作……

长期疲劳可能是导致腰痛的直接原因。

这种方法之所以有效，是因为它能同时放松腰方肌和腹斜肌。

要点：利用墙壁进行深度扭转；保持肩膀朝前；呼气时缓慢伸展。

办公室工作人员必看

这个动作我做了几十年

[冰河 @binghe]

这个健身 Skill ，我也直接公布了。

希望大家健康锻炼，量力而行！如果你有意，拿去整个 APP 也不是不行。。

都好好的，保重身体！

下载：
https://t.co/026jerdIIv

[AYi @AYi_AInotes]

喵的太魔幻了，有点 Claude 干翻 Google 的感觉😂

这个程序员老哥 Tom Turney只用7天，就把谷歌砸翻全球内存股的十亿级算法，干成了比官方承诺还快的开源实现，

谷歌只发了颠覆性的KV缓存压缩论文，半行代码都没放出来，

Tom Turney啃完论文里的数学公式，打开终端靠着Claude辅助，

7天就走完了大厂几个月的路，
前三天写完核心算法，
搭好141个测试用例，
跑通Python原型，
中间两天直接移植到llama.cpp，
写完Metal GPU内核，

最后两天疯狂优化，
把推理速度从739 tok/s干到了2747 tok/s，
纯工程优化就实现了3.7倍的提速，
他还在谷歌的方案上，
加了三项自己的研究创新，
长上下文跳过90%的value解压，
非对称K/V压缩保留key精度狠压value，老token自动降低精度，

最终成果是35B大模型，在普通MacBook上就能流畅跑，KV缓存直接压缩4.6倍，开源仓库上线一周就拿到613个星标，而谷歌到现在，

都没放出自己的官方代码，

说实话，这才是2026年最真实的写照，一个普通人加AI，就能把大厂攥在手里的核心技术，直接干成人人能用的开源工具，真的牛逼🤙

github 地址评论区自取👇

[kaize @0x_kaize]

https://t.co/ScYWvkqPa4

[Mohini Shewale @s_mohinii]

Breaking news: The CEO who created Claude just published a 38-page letter to all of humanity.

Dario Amodei mapped out exactly which careers will survive AI and which won't.

No hype. No doomsday. Just the coldest, most specific prediction any AI leader has ever made.

But page 29 contains a reasoning framework that transforms AI from what will replace you into your greatest unfair advantage.

Here are 9 prompts from Claude based on Amodei's methodology that will put you years ahead of everyone who didn't read this:

[Alif Hossain @alifcoder]

🚨 HOLY SH*T: The most complete Claude Code setup just got open-sourced.

91K+ stars.

It’s called everything-claude-code.

Inside:

→ 28 agents
→ 116 skills
→ 59 commands
→ 15+ hooks
→ 34 rules (6 languages)
→ MCP integrations
→ Built-in security scanner

This is basically a full AI engineering system.

Link 👇