At @iiserbhopal, we pride ourselves on integrating undergraduate education with high-impact research. Happy to share a new research article primarily driven by our BS-MS student Abin Sabu. https://t.co/MhOMID4Xu0 Thanks to @DBTIndia@ICMRDELHI for funding.
Our new study reveals how hypoxia-induced CTCF drives PRMT5 upregulation to rewire TCF3 splicing, promoting breast cancer invasion and EMT. Congrats to @Mutnuru_SA for key insights into chromatin regulation, splicing & metastasis! Read here: https://t.co/OGCP4fi61e
#authorinterview Deepak Pant @DeepPant94 from Prof. Sanjeev Shukla lab @ERPLab_IISERB@iiserbhopal talks about his work on "Interplay of epigenome and cancer metabolism may explain why some tumors might be more aggressive than others" @eLife#cancer https://t.co/etIoVFcGnU
Excited to share that my PhD research has been published in eLife! Grateful to @sanjeevtmc for his guidance, and to my co-authors, including @KakaniParik, for their invaluable contributions.
Excited to share our new eLife paper! Deepak Pant @DeepPant94 found that the YEATS2-GCDH axis regulates histone crotonylation, which drives the expression of the EMT-promoting gene SPARC in head and neck cancer. @iiserbhopal@ANRFIndia@ERPLab_IISERB https://t.co/bx2yYZWOJ4
Exciting work from @anchala97 and Jithin @ERPLab_IISERB. Our latest study uncovers the SRSF9-BNIP3 axis, demonstrating how alternative splicing orchestrates both autophagy & metabolic reprogramming under hypoxia. @iiserbhopal https://t.co/dITIK4dfx3
In this review, @anchala97, Ankit & Jithin from
@erplab_iiserb unravel the complex relationship between autophagy, aging & cancer. The review highlights autophagy's potential as a therapeutic target to combat age-related diseases and cancer progression. https://t.co/Syjc77jz3t
I am excited to share our new paper on #CTCF mediated loops regulates #alternativesplicing and promote #EMT in #breastcancer. Congratulations to all the fantastic Co-authors! @sanjeevtmc thanks for your guidance and enormous support 😃
New preprint! Cheers to @Mutnuru_SA from @erplab_iiserb for revealing PRMT5-mediated histone methylation promotes EMT and invasion in breast cancer hypoxia by altering TCF3 splicing. #cancerbiology#hypoxia@iiserb https://t.co/mmGBcQ6x3J