Centralising surgery: holy grail or poisoned chalice? Does concentrating surgery in specialist centres deliver better care for everyone, or does this shift in practice come at the cost of access and broader system resilience? https://t.co/tK1E6anjr2
New research on trial without catheter (TWOC) https://t.co/zwFu41vKQ5
Analysis of 672 TWOC referrals: complications ↑with catheter duration (~7% at 7 days vs 57% at 28 days), supporting earlier TWOC where safe. Older age, females, and urinary retention predict failure.
#UroSoMe
@GurorangriPadme In 1965, the PM, Mr Shastri, had appealed to the nation to miss a meal on Monday evenings due to food shortages. Most homes and all restaurants complied. There was no outrage then.
Introducing our new Virtual Stone Triage Clinic @LNWH_NHS. Early patient satisfaction and timely reviews in compliance with @NHSGIRFT guidance.
Proud to be featured in RCS Bulletin
https://t.co/cDirSQSofW
@sangharshindia@atahasnain53@ndmaindia If you had bothered to research this illustrious son of India's profile, you wouldn't have posted this vitriolic and nasty comment about this illustrious general officer and scholar.
@atahasnain53
𝐓𝐏𝟓𝟑 is the gene that encodes the tumor-suppressor protein p53. It is commonly mutated in human cancers, and as with other tumor-suppressor genes, loss of function in both alleles (i.e., two "hits") is required for tumorigenesis. Wild-type p53 protein is short-lived and expressed at low levels. Mutant p53 often has an extended life span and accumulates in cancer cells. The p53 protein is a transcription factor that controls the expression of hundreds of target genes by binding and activating specific target genes that, once transcribed and translated, suppress tumorigenesis. Mutant p53 has limited or no tumor-suppressive function because it cannot bind and activate target genes.
To learn more about this NEJM Illustrated Glossary term, read the editorial “Restoring Function to a Variant of p53 in Solid Tumors” by Xin Lu, PhD, from @Ludwig_Cancer: https://t.co/5Ox6Kuax6Q
Explore more terms: https://t.co/kobNxmaQrY
https://t.co/yR30fyvmMX A recently published meta-analysis reviews the efficacy of hyperbaric oxygen therapy in patients suffering from Fournier’s gangrene.
Our meta-analysis shows hyperbaric oxygen
🫁 ↓ Mortality
🏥 No change in LOS or debridements
Best used as an adjunct after prompt surgery + antibiotics, not alone
#Urology#Surgery#CriticalCare#EBM#HBOT@esiu
https://t.co/9gHEDZmr5h
We show that outpatient laser ablation for NMIBC is safe, effective, with good oncological control, no disease progression & minimal morbidity. @SIU_urology@LNWH_NHS@so_uro#bladder#cancer
Our study showed poor adherence to FDA guidance on complicated UTI & heterogeneity in reports, leading to a high risk of bias. Hence,we question the concept of complicated UTI as an entity. @ESIUeau https://t.co/tClON1k5Jz
@venkat_fin9@sagarikaghose Whether from India or otherwise is not significant. Blaming and defaming a political party and the government for crimes committed by a random individual in a foreign land is exceedingly prejudiced and petty. Would it be fair to blame the TMC if the person was from WB?