DermpathLove

Pathologist who loves skin, believes in pragmatism and is not a fan of pettifoggery.

[DermpathLove @DermpathLove]

Lesion L antecubital fossa - middle aged female. Any potential syndromic association? #dermpath

[DermpathLove @DermpathLove]

Update to this case - EWSR1::NR4A3 fusion. Diagnosis extraskeletal myxoid chondrosarcoma.

[DermpathLove @DermpathLove]

Middle aged M, deep soft tissue mass with widespread metastatic disease. Dx? Diffs? #BSTpath

[DermpathLove @DermpathLove]

Negative for S100, CK MNF, actin and desmin. EWSR1 rearranged by FISH. Will update when fusion partner for EWSR1 identified (hopefully!)

[DermpathLove @DermpathLove]

Middle aged M, non-specific pink papule. Dx? Further investigations needed? #dermpath

[DermpathLove @DermpathLove]

@DanGrahamMD Got it in 1! No history - but NKX3.1 positive

[DermpathLove @DermpathLove]

Male, 70s, punch biopsy scalp ?keratinocyte cancer. What is it actually? #dermpath

[DermpathLove @DermpathLove]

@joaquinnieves55 Yes, ths is poxvirus infection. PCR = cowpox

[DermpathLove @DermpathLove]

Ulcerated lesions face. A colleague's case. #dermpath

[DermpathLove @DermpathLove]

@MeredithKHerman Bilateral buttocks for chordoma

[DermpathLove @DermpathLove]

@vlodavsky66556 Lots of good suggestions here. But yes I think this is a naevus with balloon cell change.

[DermpathLove @DermpathLove]

Punch biopsy buttock #dermpath

[DermpathLove @DermpathLove]

Thanks all - middle aged female. All cells Melan-A positive.

[DermpathLove @DermpathLove]

@BarnacheaShelby cylindroma. Brooke-Spiegler syndrome?

[DermpathLove @DermpathLove]

It is ASPS (TFE3 fusion detected). Tumour had diffuse Melan-A, but no SOX10 or S100.

[DermpathLove @DermpathLove]

F, 30s, deep soft tissue mass - cbx. Lung mets at presentation. Dx, diffs? #bstpath

[DermpathLove @DermpathLove]

Thanks for all your comments, was thinking MIFS, but awaiting IHC to exclude melanoma and vascular tumour.

[DermpathLove @DermpathLove]

Middle aged female, foot, thought to be ganglion cyst - in subcutis. Would be interested to know if you're thinking, what I'm thinking, here #dermpath

[DermpathLove @DermpathLove]

So - this is an SFT - STAT6 here. Uncommon in superficial soft tissue/subcutis.

[DermpathLove @DermpathLove]

Female 20s, 'mass right upper arm - subfascial' #dermpath