This is the future of medicine.
Patients blood test should advance beyond just scanning for viral load but using the DNA ๐งฌ to map the most suitable drug that will most likely prevent the reoccurence of that sickness.
We just crossed a line in medicine that humanity has been walking toward for a hundred years.
For the first time, doctors can take a biopsy of your specific tumor, read its unique DNA mutations โ the exact fingerprint no other cancer on earth shares โ and build a custom mRNA blueprint written for one human being. Yours.
It doesn't poison the cancer. It teaches your own immune system what to hunt.
And this week, Phase 3 results confirmed it works.
Added to the best immunotherapy we already had, this individualized cancer vaccine has been dramatically cutting the odds that high-risk melanoma comes back. In the earlier data, the combination reduced the risk of recurrence or death by 49%, and the risk of the cancer spreading to distant organs by 62%, compared to the standard treatment alone. This week's Phase 3 readout confirmed the benefit holds. That is not a modest tweak. That is a different trajectory for a human life.
And melanoma is just the first door. The same approach is now in trials across lung, bladder, and kidney cancers โ a whole program of them, racing forward.
Understand what this actually means, because it's bigger than one drug.
For all of history, we fought cancer with blunt weapons. Cut it out. Burn it with radiation. Flood the whole body with chemotherapy and hope the cancer dies before the patient suffers too much. We were swinging a hammer in the dark.
This is a blueprint. A weapon designed atom by atom for one person's disease, that turns their own body into the thing that finds and destroys it. We are watching medicine shift from managing cancer to hunting it.
I've spent my life as a physician, and I did not expect to see this so soon. We were told personalized cancer vaccines were a thirty-year dream. They are happening right now, in real patients, with real data, in our lifetime.
I don't say this lightly, and I say it as a doctor who knows exactly how rare these moments are: this is one of the most hopeful things to happen in the history of the field.
I woke up thinking of the words of the morning prayer โ Modeh Ani โ I thank You. Gratitude, the moment you open your eyes, for a soul returned and a day given. To be alive at the exact hour when human beings learned to teach the body to cure itself feels like standing inside that prayer.
We are not at the end of cancer. But we are, unmistakably, at the beginning of the end of its reign.
This is sad to hear but I think she's been loving in solitary and it's making it worse for her. All she need is courage to come out (online and physically) and hangout with people that will encourage her.
It's just a phase in life and it will pass. If you're reading this, don't let go. It's just 5am and your day will soon break.
A lot of commenters said it because they don't understand that Tinubu is not a regular politician. I may not know what he is up to but when he takes the step, the same people will start commending him. Listen to Obanikoro's interview. Watch Fashola's interview and even the recent Babachir Lawal's and the common denominator is, he appears weak untill he pulls his card. Underestimate him at your peril.
This is because it takes age to know certain things in life. Even if people tell you that you're in love with a lost bird, you won't agree..emotions a clouding every sense of judgement until you come back to your sense like the prodigal son and according to this video, I don't think he has learnt his lesson.
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WACC (Weighted Average Cost of Capital) is the minimum score a business must achieve on every investment it makes.
Imagine you want to start a small clothing business and you need N1,000,000 to get started.
You get the money from two places:
- Your uncle lends you N400,000, but you must pay him 10% interest every year and
- you invest N600,000 of your own savings.
Now ask yourself:
How much should my business earn before this investment is worth it? That's where WACC comes in.
Step 1: Understand the two sources of money
- Debt (borrowed money)
Your uncle expects interest.
If you borrowed N400,000 at 10%:
You owe N40,000 every year and borrowing money has a cost.
- Equity (your own money)
Your own money isn't free either because you could have used that N600,000 elsewhere.
For example:
- Buy treasury bills
- Invest in stocks
- Start another business
Suppose you expect at least 15% return, that means your money also has a cost.
Step 2: Combine both costs
Now calculate the weighted average.
Debt: 40% ร 10% = 4%
Equity: 60% ร 15% = 9%
Total:4% + 9%= 13%
Your WACC = 13%
What does that mean?
If your business earns: 10%, that is bad.
You didn't even cover the cost of getting the money.
If your business earns: 13%, you just broke even.
If your business earns: 20%, that's excellent.
You are making more than it cost to finance the business.