Interested in heterologous expression of large numbers of biosynthetic gene clusters?
My focus over the past years has been to try to make this process more scalable.
Have a look at this new approach, I used it to discover a new antibiotic: conkatamycin
https://t.co/leqPOQZb4n
Check out my review on Non-enzymatic chemistry in natural products in ACS Chemical Reviews! So excited this review is out and bring some attention to these small but growing examples and highlight their unique mechanisms
https://t.co/jvHZStxks0
Here is a preview of our new tool, microbeMASST! https://t.co/90jUWQXKFc
Users can search for known/unknown MS/MS spectra against a database of bacterial/fungal monocultures and map the results into a phylogenetic/taxonomic tree! We are looking to expand our tree 🦠🍄🌳
So excited to share that we have not one, two, but SEVEN open positions to join the Kingdom team - we're hiring across RA and Sci levels to help deepen our scientific investment across microbial cultivation, chemistry, imaging, screening and more.
Pumped to get this paper out into the world in @JOC_OL I’m excited for everyone to see what we’ve been working on in the MacMillan lab. Shoutout to #jocelyndoesnthaveatwitter for taking me under her wing. Stay tuned for more fun with boron NMR https://t.co/q5I1WhBLga
It was amazing to have all HIFAN members and discuss all the current/future projects/upcoming papers… This was so much fun and scientifically stimulating @nadjacech @NatProdAtlas @PolyakSteve @warren_vidar
Please tag everyone else!
Ever wondered why some people are “mosquito magnets”? Thrilled to share my postdoc work mentored by @leslievosshall@RockefellerUniv @HHMINEWS. Please feast on this labor of love: >1k hrs in 80% humidity: literal buckets of blood(fed to mozzies),sweat & 500k mosquitoes’ tears!
"Much of the deeper umami flavors come from probiotic cultures (e.g., a bacteria you’d add to dairy to turn it to yogurt or cheese) sourced from Brooklyn’s Kingdom Supercultures." https://t.co/OJRGqRz7mf
I don't think people get this yet. This virus is with us for a while, and it's not going to magically go away in the next month or year.
This new paper in Science saying "prolonged or intermittent social distancing may be necessary into 2022."
https://t.co/xcL6FeNwRL
Sean Brady analyzes small molecules found in dirt and humans. Winrich Freiwald investigates how the brain processes faces. Luciano Marraffini studies CRISPR systems in bacteria. All 3 scientists have been promoted to professor at #RockefellerUniversity. https://t.co/Ky6DwjsF3y
Recent mini-review by Sean, Alex, and I on functional metabolites from human-associated bacteria. Article is focused on how techniques in natural products discovery can be applied to the human microbiome. https://t.co/hBrxODeNe9
While the upfront payment was not disclosed, Lodo is eligible for development milestone bonuses totaling up to $969 million, as well as tiered royalties based on future sales. https://t.co/xyQLLGZrRJ