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Dougan Lab
@DouganLab
Regulated proteolysis | N-degron | AAA+ machines |
#Proteostasis
views my own
Melbourne, Australia
Joined April 2015
868
Following
924
Followers
4.5K
Posts
DouganLab
retweeted
Molecular Cell
@MolecularCell
8 days ago
Online Now: Design principles of a membrane-spanning ubiquitin ligase https://t.co/4Gqc287NpC
Dougan Lab
@DouganLab
about 2 months ago
A C-degron regulates Chk1 kinase by allowing stability of inactive Chk1 and by making it short- lived upon activation | PNAS https://t.co/ggOc8bSyIh
Dougan Lab
@DouganLab
3 months ago
Molecular mechanisms of mitochondrial AAA+ proteases - Journal of Biological Chemistry https://t.co/tRmNOf5auw
Dougan Lab
@DouganLab
3 months ago
Chemical activation of mitophagy via the N-degron pathway alleviates mitochondrial neuropathies https://t.co/1X9CrevtK4
Who to follow
Andreas Kohler
@AKohler_Mito
Assistant Professor, leading the @AKohler_MitoLab @umeauniversity. Investigating mitochondrial proteostasis.
Andy Truman PhD
@TrumanLab
Professor in Biological Sciences @unccharlotte Group leader, Charlotte Group for Proteostasis Research Interested in the role of Hsp70 PTMs (Chaperone Code)
Rahul Samant
@SamantLab
Group Leader @BabrahamInst. He/him. All things #ubiquitin #proteostasis #proteomics #ageing #senescence. Spend too much on food & wine. Opinions mine, all mine!
DouganLab
retweeted
Guillaume Laconde
@Glaconde34
4 months ago
Data-Driven Design of PROTAC Linkers to Improve PROTAC Cell Membrane Permeability | JACS Au https://t.co/0Ybh7kr1CI
Dougan Lab
@DouganLab
4 months ago
Molecular mechanisms of mitochondrial AAA+ proteases - Journal of Biological Chemistry https://t.co/tRmNOf5auw
DouganLab
retweeted
Hema Chandra Kotamarthi
@HemaKotamarthi
4 months ago
Our recent work on mechanism of disassembly and reassembly of oligomeric proteins is now published in ACS Biochemistry. https://t.co/swlKg7GMpg
Dougan Lab
@DouganLab
4 months ago
CLIP-LUX: A Luminescent Split-Ubiquitin Assay Using ClpS-Mediated N-Degron Recognition for Detection of Protein-Protein Interactions in Mammalian Cells. https://t.co/q4dgRhSWrS
Dougan Lab
@DouganLab
4 months ago
Elongation Factor Tu Acts as a Chaperone to Activate an Antibacterial RNase Toxin - https://t.co/VopfnlQgBo
#ScholarAlerts
DouganLab
retweeted
Molecular Cell
@MolecularCell
4 months ago
Online Now: Mitochondria as sources and targets of cellular signaling https://t.co/LFadRnFIhD
DouganLab
retweeted
ShorterLab
@ShorterLab
4 months ago
Metabolically regulated proteasome supramolecular organization in situ: Cell https://t.co/uE5hgU773y
DouganLab
retweeted
Molecular Cell
@MolecularCell
4 months ago
Online Now: Ribosome-NAC collaboration: A regulatory platform for cotranslational chaperones, enzymes, and targeting factors https://t.co/fMaLmcskd1
Dougan Lab
@DouganLab
4 months ago
The ribosome synchronizes folding and assembly to promote oligomeric protein biogenesis https://t.co/7tOn7MTmOg
DouganLab
retweeted
ShorterLab
@ShorterLab
6 months ago
·
Philadelphia
In
@eLife
: Specific proteolysis mediated by a p97-directed proteolysis-targeting chimera (PROTAC) https://t.co/KF9kQCD3Ap
DouganLab
retweeted
ShorterLab
@ShorterLab
7 months ago
Structural landscape of the degrading 26S proteasome reveals conformation-specific binding of TXNL1: https://t.co/JOA60jIP1m
DouganLab
retweeted
MITOtalks
@MitOtalks
7 months ago
How's your juggling act? Mitochondria also have one, and the MITOtalk this week will be all about it. See you there?
Dougan Lab
@DouganLab
7 months ago
Mechanisms of assembly and function of the Hsp70-Hsp40 chaperone machinery https://t.co/WepoHudBeb
DouganLab
retweeted
Molecular Cell
@MolecularCell
8 months ago
Online Now: Delayed protein translocation protects mitochondria against toxic CAT-tailed proteins https://t.co/9CXhFvQ4Ck
DouganLab
retweeted
Cameron Thrash
@jcamthrash
7 months ago
Proteolytically activated antibacterial toxins inhibit the growth of diverse gram-positive bacteria https://t.co/os0HRbZdDi
DouganLab
retweeted
Cell Biology J-Club
@cell_club
7 months ago
The yeast peroxisomal proteome at absolute quantitative scale https://t.co/fYhvjiBLVB
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