Dr Ayush Sahu MD

MBBS (KGMU lko) , MD Internal Medicine (PGIMER CHD),DM Gastroenterology resident at AIIMS Rishikesh

[Dr Ayush Sahu MD @DrAyushdoc]

Hearing Nobel Laureate Prof. Barry Marshall at #WCOG2026 - proof that one curious mind, and a willingness to challenge dogma, can change medicine forever. #HPylori #Gastroenterology

[Anand V Kulkarni @AnandVKulkarni2]

Pathetic state. Human thinking cannot be overtaken by AI. Non sense, long ,stats based , irrelevant and impossible suggestions/ comments.
Humans have stopped using 🧠
No critical thinking.
-Victim of reviewers who use AI.

[NEJM @NEJM]

Metabolic dysfunction-associated steatotic liver disease (MASLD) affects nearly one in three adults worldwide, yet many cases remain undiagnosed until advanced fibrosis or cirrhosis develops. So, which patients should clinicians actually be screening?

In the latest episode of the Beyond Journal Club podcast from @COREIMpodcast and NEJM Group, the hosts unpack the evolving language of steatotic liver disease and discuss two major trials: MAESTRO-NASH studying resmetirom, the first FDA-approved liver-directed therapy for MASH, and ESSENCE, evaluating semaglutide in biopsy-confirmed disease.

Listen to the full episode to understand where the field is headed, which patients deserve closer attention, and how metabolic liver disease is increasingly becoming part of everyday primary care and hospital medicine: https://t.co/xJSWsDdsm6

Further reading: 
📄 Original Article by S.A. Harrison et al.: A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis (MAESTRO-NASH) https://t.co/sp7Co5pDwr
📄 Original Article by A.J. Sanyal et al.: Phase 3 Trial of Semaglutide in Metabolic Dysfunction–Associated Steatohepatitis (ESSENCE) https://t.co/9sdR9gGUOE

[Anand V Kulkarni @AnandVKulkarni2]

No need to hurry for ERCP in mild- moderate cholangitis. @alhaddad_mo
@ebtapper @drkeithsiau @stevenbollipo

[Juan Paredes @johnepm]

Real-World Effectiveness of Upadacitinib for Perianal Crohn’s Disease: A Multi-Center Retrospective Study - Clinical Gastroenterology and Hepatology https://t.co/17f6YlehaN

[Anuraag Jena @DrAnuraagJ]

Cystic neoplasms of the pancreas

A must read review article by @DrLakhtakia @krithivk @drjahangeer09

https://t.co/4topmTnrEO

[Dr. Rupa Banerjee @DrRupaBanerjee1]

Easy Reckoner !!

[Juan Paredes @johnepm]

Effectiveness and safety of JAK inhibitors in acute severe ulcerative colitis: A systematic review and meta-analysis - Clinical Gastroenterology and Hepatology https://t.co/nWyDjXOm0V

[Dr Ayush Sahu MD @DrAyushdoc]

Key steps in managing acute variceal bleeding
@APASLnews 2025

[Dr Ayush Sahu MD @DrAyushdoc]

@AimenKhanMD @ACG_EBGI @IBDMD @MLongMD @DrCoreySiegel @AmCollegeGastro @AmJGastro @JasmohanBajaj @EdBarnesMD @DCharabaty @EdwardLoftus2 @ibdtweets @UmaMahadevanIBD @MaiaKayalMD @JosephHabibi_MD @MccutchenDr @jalpa_devi @kehutchins77 @HannahWFiske @guthealingg @JHashashMD @jensemineriomd @AdamFayeMD @ReezwanaCMD @IBD_FloMD @tinahamd @ibdgijami @FarrayeIBD @Realcecum @SophieBalzoraMD @BenjamminGold @KajaliMishra @DrSamirAShah1 @SunandaKaneMD @IBD_Houston @YOGI_IBD @P_DeepakIBDMD @IBDimmunology @DrMikeDolinger @CathyLuMD @iUSCAN @BowelUltrasound @CrohnsColitisFn @saia_gi @J_Kirchgesner @bruce_sands1 @ShahidaDin1 @MLutzMD @HorstIBDDoc @ManuelBragaMD What are the recommendations for CMV testing ?

[Aimen Farooq @AimenKhanMD]

@ACG_EBGI @IBDMD @MLongMD @DrCoreySiegel @AmCollegeGastro @AmJGastro @JasmohanBajaj @EdBarnesMD @DCharabaty @EdwardLoftus2 @ibdtweets @UmaMahadevanIBD @MaiaKayalMD @JosephHabibi_MD @MccutchenDr @jalpa_devi @kehutchins77 @HannahWFiske @guthealingg @JHashashMD @jensemineriomd @AdamFayeMD @ReezwanaCMD @IBD_FloMD @tinahamd @ibdgijami @FarrayeIBD @Realcecum @SophieBalzoraMD @BenjamminGold @KajaliMishra @DrSamirAShah1 @SunandaKaneMD @IBD_Houston @YOGI_IBD @P_DeepakIBDMD @IBDimmunology @DrMikeDolinger @CathyLuMD @iUSCAN @BowelUltrasound @CrohnsColitisFn @saia_gi @J_Kirchgesner @bruce_sands1 @ShahidaDin1 @MLutzMD @HorstIBDDoc @ManuelBragaMD @fudmanMD 8/🚨 ASUC

Early, standardized🏥management

DAY1️⃣: IV steroids, 🦠CDI testing
Consider 🔦 within 24-72h
DAY3️⃣ Steroid-refractory ➡️ ⛑️ w/ IFX or CSA
🔻Albumin➡️ consider IFX dose🆙
Early🔪consult
💉Universal DVT prophylaxis
🚫 Routine antibiotics & TPN 

💊 JAK-i investigational

[Ajay Duseja @ajay_duseja]

Another study from Indian Consortium on MASLD (MASLD).
Large histology based data from 30 centres across the country suggesting that presence of T2DM doubles the risk of advanced fibrosis in MASLD.
Thanks Narendra @drnschoudhary and all investigators.
https://t.co/dhGJuiKQak

[Dr Kamlesh Darji @DrKamleshDarji1]

Residency Tip:

One day you’ll realize the scariest thing about residency is not the workload.
It’s that you can function while breaking.

You’ll talk normally.
Work efficiently.
Answer questions correctly.

And inside - there will be NOTHING!
No anger.
No sadness.
No pride.

Just emptiness that doesn’t ask for help.
You will learn how to smile while being humiliated.
How to say “okay, sir” when something inside you screams “this is wrong.”
How to keep working even after your self-respect quietly leaves the room.
You won’t notice the moment it happens.

It happens slowly;
when you stop expecting fairness,
when rest feels undeserved,
when exhaustion becomes your baseline personality.

The system will not clap when you endure this.
It will simply assume you always could.

And here is the part no one prepares you for:
One day, much later, when life becomes calmer -
you will struggle to relax.
Because your nervous system learned that peace is unsafe.

So remember this, before you lose it completely:

If you feel numb, you are not lazy.
If you feel detached, you are not heartless.
If you feel empty, you are not ungrateful.
You are injured, not weak.

Residency doesn’t just teach medicine.
It rewires how much pain you think you deserve.

But here is the truth that saves you:

Nothing about this season is permanent.
And nothing it takes from you is gone forever.

The discipline you’re building will one day protect you.
The silence you’re enduring will one day give you authority.
The pain you’re surviving will become judgment that no exam can test.

One day, you will work on your own terms.
You will choose whom to listen to.
You will walk into rooms where no one can raise their voice at you.
And when that day comes,
you won’t need revenge, validation, or applause.

Because you’ll know - you were forged in a place that tried to erase you and failed.
So don’t try to shine right now.
Don’t try to prove anything.

Just stay.
Just stay.
Just stay.

Your time is not lost.
It is being converted into power.

BIG DOCTOR IN MAKING.

[Dr Ayush Sahu MD @DrAyushdoc]

When the Gut Turns Brewery: Microbial Ethanol Production and Hidden Alcohol Exposure, must go through recent article in nature.

[Vishal Sharma @drvishal82]

Rare honor for a doctor to lead the illustrious list of Padma awardees this year- the journey of Dr DN Reddy is truly inspirational.

Congratulations to a humble human being who incidentally is a PGI alumnus

[Nico Gagelmann @NicoGagelmann]

Ten rules for the medical resident

1. Be truthful.
Practice medicine the way you would want it practiced on you. Integrity in thought, speech, and action is non-negotiable.

2. Stay organized.
Your cognitive bandwidth is finite. Use systems (calendars, lists, routines) to reduce chaos and prevent avoidable errors.

3. Learn from mistakes.
You will err. Analyze failures honestly, correct course, and do not repeat them. Reflection is a professional obligation.

4. Ask.
Ignorance concealed is dangerous. Seek input from seniors, peers, nurses, and allied staff early and without embarrassment.

5. Communicate clearly.
Medicine fails when communication fails. Be precise, listen actively, avoid jargon, and confirm understanding.

6. Listen to patients.
Symptoms, fears, and values are data. Attention is not optional; it is diagnostic and therapeutic.

7. Stay sane.
You will encounter suffering, injustice, and death. Remain lucid and mentally intact. Protect time for recovery, burnout helps no one.

8. Stay curious.
Clinical competence decays without inquiry. Read, question, and adapt as evidence evolves.

9. Stand up.
Have principles. Authority does not equal correctness. Advocate for patients and for sound medicine, even when uncomfortable.

10. Be sincere.
Remember why you entered medicine. Let purpose, not convenience or fear, guide your conduct.

"A good doctor in a privileged or shitty hospital is still a good doctor" taken from my good @nihardesai89

[Vishal Sharma @drvishal82]

🚨 Gap in Latent TB Screening for IBD Patients

New multicentre study from India reveals porous latent TB screening for IBD patients
Key findings:
-Only 59% compliance with standard screening
- Annual screening neglected
Full study here https://t.co/5q7OAm9TCg

[Therapeutic Advances in Gastroenterology @TAGastroenterol]

This Danish population‑based cohort study links PPI use to higher IBD‑related hospitalisation and surgery, likely reflecting protopathic bias but raising questions about long‑term PPI safety in IBD. #PPI #IBDOutcomes #IBD #GIResearch https://t.co/5Jv3xFjX7N

[Yujun_Wong @Yujun__Wong]

Interested in #recompensation in cirrhosis?

👋🏻Join May xuan sharing this today at poster #2356 today

#tlm25 #liverfellow #liverx

[Jasmine Sethi @JasmineNephro]

🔥🔥🇮🇳Nation is burning

🔥PGIMER Chandigarh resident doctors are on strike in support of our colleagues in Kolkatta #RGKarHospital against the heinous brutal crime (Gang Rape and murder of a resident doctor on duty)

🔥Faculty association too stands in solidarity with the residents

🔥Central Protection Act is the need of hour

#RGKarHospital #RGKARmedical #KolkataDoctor #KolkataDoctorDeath