EFS not a surrogate for OS in M0 prostate cancer treated by RT. Great work @Wanling50578056 @Merregan @ChrisSweens1#ICECaP@PCF_Science Continuing to inform trial design in this space. https://t.co/y2KZmydrZk
The time is now to #FlattenTheCurve. Success depends on proactive, aggressive approach with complete buy-in. #SocialDistancing is bare minimum. Personally, I will try to avoid all cafes, restaurants, the gym, etc. I strongly urge all to consider the same #COVIDー19#coronavirus
@DrRanaMcKay@DrChoueiri@Dominick_Bosse@Cold_Steel_1970 Excellent work & agree with this strategy as a 'litmus test' to see which int risk pts you may consider for CN down the line. Have also used for non-met disease if poor GFR & hopeful to use partial nephrectomy 👍
Fantastic work by @Dominick_Bosse and colleagues. Valuable data to factor into treatment approach algorithm esp if considering CN as part of the package
Thank you ASCO Direct Highlights Denver & @TotalHealthConf for the opportunity to discuss the most impactful #ProstateCancer abstracts from #ASCO19! Lots of great advancements to move patient care forward
Thanks to all the teams from Australia, New Zealand, Canada, @DanaFarber, Ireland and UK who all supported the #ENZAMET trial. Thanks also to @ASCO for choosing it as a plenary presentation based on the clinical practice & biology informing data for mHSPC @ANZUPtrials@Uromigos
Initial look at selected genes from WES of tumor with relationship to outcome from PSMA-TRT in #prostatecancer, perhaps not too surprising BRCA2 favorable TP53 unfavorable #GU19 - look forward to further analyses in larger dataset with @PCF_Science and @CDMRP funding
Dr. Lotan @UTSWUrology reminds us that many pts with localized muscle invasive #bladdercancer are higher stage than we think. Therefore we are missing pts who may beneft from neoadj systemic rx. Biomarkers/subtypes are poised to help our ability to identfy these pts #GU19#blcsm
@g_develasco Hard to say. Total population in ARCHES doing quite well, incl placebo arm & even with ~2/3 being high volume. Compare with LATITUDE where ~1/2 in placebo dead at 3 yrs. Maybe less risky pop OR doce pulled OS up in placebo arm. Plus short F/U...
Love @Prof_IanD's focus on CE in his abst discussion - needs to be a consideration in ALL data interpretation. BUT now what? XRT to primary for LV dz? Doce for HV? Abi + XRT for N0/N1? Let alone sequential a la #ARCHES TBC... #GU19