Drisya Vijayakumari

Researcher
🧬📝💬

[Dr. Anthony Letai @NCIDirector]

To stay ahead of cancer, we need to understand how tumor cells adapt. This @theNCI study reveals how environmental stress can drive heritable changes in gene expression, offering new insights into one of cancer’s greatest challenges: drug resistance. https://t.co/moyvsyouMc

[Rajiv Kumar Jha @Rajiv_K_J]

Our new preprint is out @biorxiv, please check it out.

https://t.co/fFtSLHABL8

[Drisya Vijayakumari @DrisyaV1]

Congratulations @grewalsh @bharatbhatt91 @Yi_Wei0909 @JothyDjothy @ShwetajainX and all the coauthors for this amazing work! This study uncovers the mechanism of how you get an epigenetic makeover! Learn more about it here👇

[Shiv Grewal @grewalsh]

Stress controls epigenetic inheritance!

A histone ubiquitylation-based regulatory hub links stress/environmental signaling to heterochromatin self-propagation and epigenetic inheritance-reshaping how we think about development, drug resistance and cancer👉https://t.co/Wf8y1HjHEX

[Shiv Grewal @grewalsh]

Stress controls epigenetic inheritance!

A histone ubiquitylation-based regulatory hub links stress/environmental signaling to heterochromatin self-propagation and epigenetic inheritance-reshaping how we think about development, drug resistance and cancer👉https://t.co/Wf8y1HjHEX

[Drisya Vijayakumari @DrisyaV1]

Congratulations again Sahana. Very Happy and proud of you. Looking forward to seeing many more accomplishments come your way. Very best for the new start!

[Sahana Holla @holla_sahana]

Thrilled to share that I’ve joined @TIFRH_buzz as an Assistant Professor! Deeply grateful to my mentors (esp @grewalsh and KN Balaji), colleagues, friends, family & EVERYONE who made this possible. Excited to explore Epigenetics & the 3D Genome with the brilliant minds in India!

[Sahana Holla @holla_sahana]

Thrilled to share that I’ve joined @TIFRH_buzz as an Assistant Professor! Deeply grateful to my mentors (esp @grewalsh and KN Balaji), colleagues, friends, family & EVERYONE who made this possible. Excited to explore Epigenetics & the 3D Genome with the brilliant minds in India!

[Shiv Grewal @grewalsh]

Congratulations @rakesh_k_sahu

[Shiv Grewal @grewalsh]

🔬 Decoding Silencing: How Heterochromatin Transcribes to Silence Itself!
🧬Our latest research reveals how a pioneer transcription factor-like complex PhpC/NF-Y infiltrates repressive heterochromatin, generating transcripts with hidden introns that kickstart RNAi-mediated heterochromatin formation
https://t.co/LMzKtyhlPu

[Drisya Vijayakumari @DrisyaV1]

Congratulations on this amazing work @grewalsh @SrivastavManjit and all the co-authors

[Drisya Vijayakumari @DrisyaV1]

@grewalsh @holla_sahana @DBTIndia Big congratulations @holla_sahana Well deserved!! So happy for you

[Shiv Grewal @grewalsh]

📢ACCESS DENIED!!
Ever wonder how heterochromatin causes transcriptional gene silencing and is epigenetically inherited?
Excited to share our new story showing that histone deacetylation, a conserved feature of heterochromatin domains from yeast to mammals, limits access to SWI/SNF chromatin remodelers to prevent unraveling of nucleosomes, which enforces gene silencing and maintains high H3K9me3 density required for epigenetic inheritance
#epigenetics #heterochromatin #histones #chromatin

Congratulations to @rakesh_k_sahu and other lab members!
https://t.co/Q6ebM1zBBR

[Drisya Vijayakumari @DrisyaV1]

Congratulations @rakesh_k_sahu @grewalsh and other authors for this elegant work!

[Shiv Grewal @grewalsh]

📢ACCESS DENIED!!
Ever wonder how heterochromatin causes transcriptional gene silencing and is epigenetically inherited?
Excited to share our new story showing that histone deacetylation, a conserved feature of heterochromatin domains from yeast to mammals, limits access to SWI/SNF chromatin remodelers to prevent unraveling of nucleosomes, which enforces gene silencing and maintains high H3K9me3 density required for epigenetic inheritance
#epigenetics #heterochromatin #histones #chromatin

Congratulations to @rakesh_k_sahu and other lab members!
https://t.co/Q6ebM1zBBR

[Shiv Grewal @grewalsh]

📢Job Opening COMPUTATIONAL STAFF SCIENTIST🌟

The Laboratory of Biochemistry and Molecular Biology (LBMB) at NIH is seeking a Computational Staff Scientist to analyze transcriptional and post-transcriptional processes in eukaryotes. Full job ad here 👉https://t.co/CqeGSdoJLH

[Shiv Grewal @grewalsh]

How DNA Replication Machinery Ensures Chromatin Assembly and Epigenetic Inheritance https://t.co/dmaLlD073L via @growkudos

[Shiv Grewal @grewalsh]

📢An elegant dance between replication and histone retention for epigenetic inheritance!🥳Our new work shows that heterochromatin domains are specialized replication zones that preserve parental modified histones to ensure self-templated chromatin assembly https://t.co/JWXeySNvBC

[Drisya Vijayakumari @DrisyaV1]

Congratulations @grewalsh @pnathanailidou @holla_sahana for this amazing work and insight on how specialized replication zones helps preserve heterochromatin!

[Shiv Grewal @grewalsh]

📢An elegant dance between replication and histone retention for epigenetic inheritance!🥳Our new work shows that heterochromatin domains are specialized replication zones that preserve parental modified histones to ensure self-templated chromatin assembly https://t.co/JWXeySNvBC

[Drisya Vijayakumari @DrisyaV1]

Congratulations @grewalsh Diego and Hua for this amazing work!!

[Shiv Grewal @grewalsh]

📢 Exciting news! 🎉 Our recent paper is now published, showcasing the crucial role of the cysteine-rich domain in CENP-A chaperone Scm3/HJURP for centromere targeting and kinetochore integrity! https://t.co/CYVSUuDsyR🥳

[Rajiv Kumar Jha @Rajiv_K_J]

MYC function and regulation in physiological perspective https://t.co/bYJP2N0DAK

[ISRO @isro]

Chandrayaan-3 Mission:
'India🇮🇳,
I reached my destination
and you too!'
: Chandrayaan-3

Chandrayaan-3 has successfully
soft-landed on the moon 🌖!.

Congratulations, India🇮🇳!

#Chandrayaan_3
#Ch3

[Drisya Vijayakumari @DrisyaV1]

@MZamzam2020 @iiscbangalore Congratulations 🎉