Duc Tran

process scientist @JanssenEMEA

[Duc Tran @DucTran23]

Another interesting project that I was involved is now published in @JOC_OL. We expanded the scope of Heck coupling to make aryl pyruvates and (unexpectedly) ortho ester https://t.co/M6RKwo7itF

[Duc Tran @DucTran23]

@HonestChemist1 @SafeChem79 There is always a balance to make but Pd should not be an issue at ~10ish kg scale (optimization required).

[Duc Tran @DucTran23]

@GusTheChemist Largazole was a total synthesis target of several groups (ACIE, JACS … ~2007-2008) and the synthesis has been scaled up by pharma (OPRD a few years later)

[Chemistry at Thieme @thiemechemistry]

❇️ In this Synfact of the month @DirkTrauner from @nyuchemistry highlighted the ´Process Development for the Synthesis of Hepatitis C NS5A Protein Inhibitor Odalasvir` by Tran DN. and co-workers from @JanssenGlobal.👏
👉 https://t.co/9OzqNJpXZm

[Duc Tran @DucTran23]

@SafeChem79 Fully agreed. Chrom is the first thing to remove if you want to increase throughput. It is not only about crystallization but also means cleaner reactions, higher selectivities, simpler by-products …

[Duc Tran @DucTran23]

@ThanhVQNguyen After some investigation, it was just the organic solvent left in piping … the operator forgot to purge the line before sampling 😅

[Duc Tran @DucTran23]

Typical process chemist’s life: when the plant engineer texted you at 9 pm because the sample of water layer have 2 layers in it and they don’t know what to do next … 🤨

[Duc Tran @DucTran23]

@GusTheChemist @LcsoLab @enscmchimiemtp Fully agreed :)

[Duc Tran @DucTran23]

@TPolymerist I am also 6 years in industry now (time goes fast) and having the same thoughts/questions as you… Thanks for sharing.

[Duc Tran @DucTran23]

Preparation for Tết - lunar new year

[Duc Tran @DucTran23]

@rubenR2D2 I am also not sure about that specific requirement … but if you like the position and fit 60-70% requirement, feel free to apply :) don’t let that hinders your opportunity.

[Duc Tran @DucTran23]

Our Switzerland colleagues are looking for an entry level for process R&D (Organic chemistry) #chemjobs https://t.co/XRgmyMwedd

[Duc Tran @DucTran23]

Janssen is looking for a PhD entry level for Med Chem in Beerse, Belgium #chemjobs https://t.co/bOZf9MKkJZ

[Duc Tran @DucTran23]

@ckellzchem @coal_carter Cyclohexane is also less toxic than hexane.

[Christopher Kelly @ckellzchem]

Next June @JanssenUS will be hosting its inaugural GSS our PA Site! For those 3rd/4th year students interested in presenting their work and learning about our AWESOME research environment, apply by Jan 15 to [email protected] #Janssenchemistry #RealTimeChem

[Duc Tran @DucTran23]

We are looking for Protein Engineer biocatalysis in Belgium #chemjobs link: https://t.co/ZQ60jI9eXe

[Duc Tran @DucTran23]

@Chem_Walker Actually a well written research summary might help you there: total synthesis of a challenging natural product using different strategies without achieving the final target (thus no pub), you should still be ok for an interview (if I can decide 😊)

[Duc Tran @DucTran23]

@Chem_Walker Indeed, pubs does not matter at all in the interview round. But with current recruitment system, your cv + research summary need to stand out to secure that interview first …

[Duc Tran @DucTran23]

@awhspeed It is hard to compare 2 reagents without context (purpose, synthesis route, reaction conditions, process …).

[Duc Tran @DucTran23]

@SafeChem79 It was really fascinating for me when I first learnt and saw the IS test for a process safety.