We are grateful for this incredible support to advance our research on Type 1 Diabetes. Together, we're making strides toward a cure! Learn more about our work here: https://t.co/D8UDWMib6W #DiabetesResearch#T1D#ScientificBreakthroughs#ThankYou
Meet the researcher: Daniel Veronese Paniagua. Danny (@dveronese18) is a PhD student in the Millman lab with a recent preprint on viral infection of islets as a possible cause of #Diabetes . Check out his full meet the researcher writeup at this link: https://t.co/eQCQjM6Mn3
We published a review on the advancements in the use of stem cell-derived islets (SC-islets) for diabetes research and treatment. Congrats Marlie Maestas and Maggie Bui! https://t.co/G9RFC7aLP3 @WUDeptMedicine @WUSTLdbbs @WashUEndo
Great summary of our work by my mentor, @JeffreyRMillman, on the impacts of Coxsackievirus B3 infection on the various cell types found in cadaveric islets. Make sure to give my first first-author paper a read!
How do different cell types in the pancreas respond to Coxsackievirus B (CVB) infection? Our new preprint investigates this. CVB infection has long been associated with the onset of Type 1 diabetes (T1D). 🧵to follow https://t.co/A9qwNEuh44 @WashUEndo @WUDeptMedicine @WUSTLdbbs
We find that although the virus infects all cell types at similar rates, it induces unique, cell-type specific transcriptional responses. We also report on the effects of CVB on mitochondria in beta and alpha cells and identify MIR7-3HG as a potential antiviral therapeutic target
I am excited to announce the latest pre-print on bioRxiv from the Millman lab! It happens to be my first ever first-author manuscript as well.
Give it a read!!
https://t.co/lnmI0u1Sc3
In this study, we performed single-cell RNA sequencing on human cadaveric islets treated with Coxsackievirus B (CVB) and poly(I:C), a viral mimic, to delineate the transcriptional response induced by the various cell types.
The first publication for my PhD thesis is finally out. This study focuses on water loss and hydration in Urosaurus ornatus. Great collaborative work with @LizardProf Here the full text https://t.co/vKlzk4u5wI
@ICB_journal
🧬 Exciting new study out in @NatureComms! We identify cell-type-specific responses in pancreatic islets to stress, shedding light on diabetes progression. It is #OpenAccess for all to download for free! #DiabetesResearch@WUSTLmed @WUDeptMedicine https://t.co/7s0534QwYu
Congratulations to our @wustlcrm post-bacc @MasonSchmidt22 for his #OpenAccess publication! We integrated scRNAseq datasets of human SC-islets from several protocols along with primary islets to study variation in cellular identity across states & context https://t.co/W0tQpTdh6f
This afternoon, we have 2 posters being presented at 1:30p. Daniel Veronese Paniagua poster#807 Coxsackievirus elicits distinct cell-type responses in pancreatic organoid model. Kameron Bradley poster#805 on Hypoxia-induced β cell demise & dysfunction pathways #ISSCR2023
How do we use the latest in computational analysis to improve cells for diabetes cellular therapy?
We published today in @NatureCellBio a detailed multiomic study of stem cell-derived islets (SC-islets) & natural islets at single-cell resolution.🧵inc'ing https://t.co/LsZ9Oncwqz
One of my highlights throughout my academic career has always been helping the local community and inspiring the next generation of STEM leaders from URM
Cell replacement therapy for #diabetes is on the horizon! Check out the latest developments in our @CellStemCell#OpenAccess review: https://t.co/oJRLWo2jzY
Latest from us: @CellStemCell#OpenAccess review highlighting recent advances in the generation and characterization of highly functional islets from stem cells for #diabetes as well as strategies to ensure graft viability & safety after transplantation 🧵https://t.co/c99tBBgdUZ
Congratulations Dr. Augsornworawat @punnaug for successfully defending his PhD dissertation on single-cell sequencing analysis of stem cell-derived islets for #Type1Diabetes therapy! @WashUBME @WashUEndo