Eleanor Sanderson

Lecturer in Medical Statistics. Research focuses on Mendelian randomization and instrumental variables.

[Amanda Hughes @ammhughes]

How much does a child's BMI affect their depression, anxiety, or ADHD symptoms? Not much, suggests our new research which accounts for family-level factors. Read it here: https://t.co/m3OIYm4mOS. With @ECSanderson @nm_davies @laurahowe_epi @alexhavdahl @bristimtom @mrc_ieu

[JBMRPlus @JBMRPlus]

Check out our new Editor’s Pick from @JBMRPlus Associate Editor Emma Clark @emcbristol! A Guide for Understanding and Designing Mendelian Randomization Studies in the Musculoskeletal Field
@MRC_IEU @Brms_Research @BristolUni (1/6)

https://t.co/SzsxrbzLFv

[Nature Reviews Methods Primers @MethodsPrimers]

This Primer explains Mendelian randomization - from concepts to required conditions - and describes key applications and applying the technique to growing genomic datasets @MariaGlymour @mvholmes @MarcusMunafo @jeanv_morrison @chr1swallace

https://t.co/9klmsOW4sO

[IJE @IntJEpidemiol]

Interpretation of Mendelian randomization using a single measure of an exposure that varies over time
https://t.co/SHLVgEz5ol

[Ciarrah-Jane Barry @Ciarrah_]

So excited to see our UK Biobank study comparing intergenerational instrumental variable analyses of BMI on mortality published in @IntJEpidemiol !!

https://t.co/9tYz449mMS
🥳

[Hannah Elliott @hannah_elliott]

New paper assessing causality of DNA methylation associations with prevalent type 2 diabetes. Congratulations to @Dianajuvi89 for leading the work, very lucky to work with you! @carolinerelton @ECSanderson @ammegandchips @mrc_ieu #diabetes #MR https://t.co/Dgt232930S

[george davey smith @mendel_random]

Mendelian randomization outlined by ⁦@ECSanderson⁩ at #Mendel200

[Eleanor Sanderson @ECSanderson]

New preprint out! In it we propose a (simple!) solution to the bias caused in Mendelian randomization from covariate adjusted GWAS statistics https://t.co/Z3e2h8uz4k
Led by PhD student Joe Gilbody, also thanks to @MCarol_Borges and @mendel_random!

[MRC IEU @mrc_ieu]

This is happening tomorrow! Thank you to all our speakers, helpers and all who've registered to join us (not too late if you want to join us online!). See you tomorrow! #Mendel200

[Eleanor Sanderson @ECSanderson]

Thanks to everyone involved with this! @mendel_random @iTomRichardson @bristimtom and Kate Tilling!

[Eleanor Sanderson @ECSanderson]

Our new paper on using Multivariable MR with multiple measures of a single exposure was published today. In it we discuss the approach, the assumptions required and interpretation of the results. https://t.co/svU3gfArJg

[MR_lit @Mendelian_lit]

Estimation of causal effects of a time-varying exposure at multiple time points through multivariable mendelian randomization https://t.co/1PU29VvK5l

[MR_lit @Mendelian_lit]

Interpretation of Mendelian randomization using a single measure of an exposure that varies over time https://t.co/vQ90zQT5lR

[Joshua Bell @joshuaa_bell]

Finally: causal estimates for adiposity & metabolomic traits at scale!

Pleased to share the first large-scale comparison of conventional vs MR approaches in UK Biobank in @LancetRH_Europe

https://t.co/FfQboXmpA9

Key takeaways:

[Caroline Bull @caroline_bull]

Our preprint “Separating the effects of early and later life adiposity on colorectal cancer risk: a Mendelian randomization study” is now available: https://t.co/UBn1451qgE

[george davey smith @mendel_random]

Excited to thumb through an actual hard copy of the book “Combining Human Genetics and Causal Inference to Understand Human Disease and Development” edited with @BeckyRichmond90 and Jean-Baptiste Pingault, a thread on what it contains /cont

[MRC IEU @mrc_ieu]

See the programme for our upcoming #Mendel200 conference to celebrate the bicentenary of Gregor Mendel. A great line up of speakers and topics. Join us online (free) or in person in Bristol, UK (small, subsidised price) https://t.co/8jTSFl31yG

[MRC IEU @mrc_ieu]

From pea plants to better understanding of public health ... our upcoming conference celebrates the 200th birthday of Gregor Mendel, his legacy and the range of research his work has inspired. Join us in person in Bristol or online on 20-21 July #Mendel200 https://t.co/1Ls0lMsWAv

[george davey smith @mendel_random]

A limited number of in-person places now available at the “Mendel @ 200” meeting 20-21st July. https://t.co/RxxrSVVcSd

[Sarah Lewis @ProfSarahJLewis]

**Funded PhD studentship at University of Bristol - to develop methods for applying Mendelian randomization in diverse populations and to apply these to identify risk factors for gallbladder cancer
https://t.co/W8ilk9m4bB