Happy to share the latest from Mike Kiritsy's thesis work - a comparative CRISPR screen identifies a new link between metabolism in immunity, and begins to differentiate the diverse effects of IFNg: https://t.co/zmIfuHjwJs
I’m REALLY excited for our new study to be posted! In collaboration with @SassettiLab this story pushed us in lots of new directions leading us to uncover a key role for Mitochondrial respiration in IFN-gamma responses in macrophages! A thread:
If you are interested in interactions between host immunity and mycobacterial respiration, check out the preprint of my first, (co)first-author paper! Big thanks to everyone involved! @SassettiLab@andolive85
Another interesting one from the @SassettiLab! Read more for some cool insights into host immunity, pathogen respiration, and low pH! Some great work by @EJaecklein!!! https://t.co/tyu7mskSkG
I'm so excited for the first research article from my group to be posted! There is CRISPR, RNAseq AND T cells! Something for everyone! It was an amazing effort by @LaurisaAnkley and Mike Kiritsy in collaboration with @FitzgeraldKate. Thought I'd do a quick thread to explain: 1/11
Thrilled to share our @SassettiLab research investigating how Mycobacterium tuberculosis survives during antibiotic treatment published in @mSystemsJ! https://t.co/g7zxXUfPfV
@ryan_richards33 and @TheLeeLab found that drug combinations comprised of two cell death targeting drugs are enriched for antagonism and “single agent dominance". https://t.co/7JLuBd667y
Our lab just posted a new preprint which shows how ELP-dependent expression of MCL1 promotes resistance to EGFR inhibition in triple-negative breast cancer cells. Congrats @CruzgordilloP@meganhoneywell and the rest of the team! https://t.co/IXBgyjKA27
New preprint from the @SassettiLab! A fun collaboration with Sishir Subedi and Tom Ioerger, our friends from TexasA&M. Hope you all have an enjoyable read!
https://t.co/maxGA0L6Wg
A thread of some cool things we found....
HIV, Ebola, and Zika are deadly, intricate viruses. Structural biologist David Goodsell helps communicate about them with precision through his watercolor paintings. https://t.co/0G8XvNqPDz