Earthroamer 🌍

#Biotechinvestor #Goldbug

[Redeye @Redeye_]

Redeye is optimistic about the advancement of nadunolimab into the phase IIa part of the investigator-sponsored study.

$CANTA

https://t.co/DCErWuiqob

[BioStock @BioStock_SWE]

Cantargia presenterar tidiga resultat från en prövarinitierad fas Ib/IIa-studie med nadunolimab vid högrisk myelodysplastiskt syndrom och akut myeloisk leukemi. https://t.co/RmBK0cTH5b

[FrillePelle @FrillePelle]

Cantargia presenterar prekliniska resultat som visar tumörhämmande effekter av nadunolimab i metastatisk kolorektalcancer

$CANTA #IL1RAP

https://t.co/QxSrWRrGT2

[FrillePelle @FrillePelle]

Our base case of SEK8.5 includes a risk-adjusted late-stage deal with nadunolimab in 2030 on the back of a
positive pancreatic cancer phase III study, with a total deal value of USD3bn of which USD1bn upfront and 25%
royalties

$CANTA #CANTARGIA

https://t.co/0KFeSwJCui

[Earthroamer 🌍 @Earthroamer75]

@henrikbmoller @cantargia Inte företagets konto...

[Rodger Sherman @rodger]

the last thing you see before you die when you're a USA curling stone in scoring position

[FrillePelle @FrillePelle]

Myeloid-stromal IL1RAP as a therapeutic vulnerability in pancreatic cancer

“These findings support an upcoming neo-adjuvant trial combining CAN04 with chemoimmunotherapy in patients with operable PDAC”

CANTARGIA #IL1RAP $CANTA

https://t.co/f1gYxpvnli

[FrillePelle @FrillePelle]

”Den vetenskapliga motiveringen för att använda en ny IL1RAP-riktad metod med nadunolimab är övertygande, och vi ser fram emot att generera data som kan ge framtida immunterapistrategier”

$CANTA #CANTARGIA #IL1RAP

https://t.co/l3iPJnXAgd

[Earthroamer 🌍 @Earthroamer75]

@oplatsen @HerrFlax De har ju packat LB i lastbilar tidigare, så kör från fartyg. D-boys igen?

[FrillePelle @FrillePelle]

Ytterligare en IL1RAP antikropp inom autoimmuna och inflammatoriska sjukdomar, kan bli intressant när det blir kommersiella produkter mot IL1RAP när Cantargia sitter på både produktpatent men även måltavlan IL1RAP för antikroppar.

$CANTA

https://t.co/Jabie757vJ

[FrillePelle @FrillePelle]

Intressant utveckling inom IL1RAP
Sanofi och Almirall är på väg in i fas 2 med sina IL1RAP-antikroppar mot HS – samma indikation som Otsuka utvecklar CAN10 för.

Båda företagen har överklagat Cantargia's IL1RAP-patent flera gånger i EU, US och JP… men förlorat varje gång.

[FrillePelle @FrillePelle]

CANTARGIA at AACR PDAC 2025

These data collectively suggest that IL1RAP is highly relevant in PDAC and can be meaningfully targeted by Nadunolimab

These findings support an upcoming neoadjuvant trial combining Nadunolimab with chemoimmunotherapy in patients with operable PDAC

[Cancer Discovery @CD_AACR]

Read the just-published article mentioned in this story: Elevated clonal hematopoiesis in 9/11 first responders has distinct age-related patterns and relies on IL1RAP for clonal expansion https://t.co/ceyiI1amKO

[Earthroamer 🌍 @Earthroamer75]

@Longterms1 @Gothiaace Tänk på, men tänk hela vägen...

[Earthroamer 🌍 @Earthroamer75]

@Longterms1 @Gothiaace Långt ifrån första gången, just saying....

[Divij Verma @Divijv]

We also identified a critical role for IL1RAP in exposure-induced CH, suggesting a new therapeutic opportunity. (3/8)

[Earthroamer 🌍 @Earthroamer75]

@Longterms1 @Gothiaace Ge upp Gothia., han kommenterar inte ens det senaste från AACR. Cherrypicker som hypar sina egna innehav som svansen köper upp åt honom.

[Raffaele Di Giacomo, PhD @sciqst]

Congratulations on the presentation! Exploring IL1RAP inhibition could significantly advance the fight against #PancreaticCancer, which has shown resistance to many conventional therapies. Can you share what specific chemoimmunotherapy combinations you're investigating, or how far along you are in the clinical trial phases? #Medicine

For more in-depth reviews on similar biomedical strategies, check out https://t.co/4Y9Imt8uIJ, a platform that aids in understanding the complex landscape of biomedical research by generating comprehensive reviews.

[Jash Datta, MD @DrJashDatta]

We are delighted to present our study & partnership with @cantargia 🇸🇪 at #AACRPan25 to move fwd #IL1RAP inhibition as a strategy to improve chemoimmunotherapy sensitivity in #PancreaticCancer - some BIG news to come soon! @SylvesterCancer @PeterHoseinMD https://t.co/SoyQHhmU5Y

[Andy Lane @lane_andy]

Elevated clonal hematopoiesis in 9/11 first responders has distinct age-related patterns and relies on IL1RAP for clonal expansion https://t.co/MTeYS1AxjT @Amitvermamds @SteidlUli