If babies understood embarrassment, most of them would never learn to walk or speak because of the amount of failure required to improve.
This was one of our first lessons in life but somehow, we forgot
The seminal paper of Shimon Sakaguchi published in 1995 @J_Immunol where he discovered CD4+ CD25+ cells that actively suppress autoimmunity. It was the first time T regulatory cells appeared in the literature. Not all Nobel Prize winning work need to be in glamorous journals.
Our immune system is an evolutionary masterpiece. Every day it protects us from the thousands of different viruses, bacteria and other microbes that attempt to invade our bodies. Without a functioning immune system, we would not survive.
One of the immune system’s marvels is its ability to identify pathogens and differentiate them from the body’s own cells. The microbes that threaten our health do not wear a uniform – they all have different appearances. Many have also developed similarities to human cells, as a form of camouflage. So how does the immune system keep track of what to attack and what to protect? Why doesn’t the immune system attack our bodies more frequently?
Researchers long believed they knew the answer to these questions: that immune cells mature through a process called central immune tolerance (see image). However, our immune system turned out to be more complex than they believed. Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi have been awarded the 2025 Nobel Prize in Physiology or Medicine for their discoveries concerning peripheral immune tolerance.
Tu Youyou became the first mainland Chinese scientist to be awarded a #NobelPrize in a scientific field - for discovering artemisinin, a malaria cure that’s saved millions. Today we reveal the 2025 medicine laureate. Stay tuned.
A documentary about the R21 malaria vaccine that I invented ~13 years ago while working in Oxford is airing tonight, 8pm BBC2!
After I left Oxford ~10 years ago, many wonderful people continued to develop the vaccine, and as of last week the vaccine is now finally being rolled out in Africa!
#TheBattleToBeatMalaria #R21 @DrMSDatoo@HalTinto@Fredros_Inc@ally_olotu@SerumInstIndia@JennerInstitute@Novavax
https://t.co/IaaevIRZwv.
Congratulations to Katalin Karikó from Hungary & Drew Weissman from the US on winning the Nobel Prize.
Their pioneering work paved the way for mRNA vaccines.
This recognition shows the crucial role of science in defeating COVID-19 and liberating the world from the pandemic.
Hypertension drug I used to buy at 120ghc is now almost 4 times the cost.
Every month I walk into the pharmacy and the price has increased.
#OccupyJulorbiHouse
The crazy thing is that the government legit thinks this is all propaganda and an activity fueled by the opposition. They don’t really believe Ghanaians are suffering. They think it’s just a bunch of riffraffs being silly smh. #OccupyJulorbiHouse
You know the crazy thing about the measles outbreak? The vaccine shortage was not because we couldn’t pay for vaccines, they just neglected to pay the supplies for vaccines charley, it wasn’t a priority…
#OccupyJulorbiHouse
I am actively tweeting #OccupyJulorbiHouse today because the minimum wage in this country is gh13 a day! Meanwhile, a sanitation minister has millions of cedis in her house! On top of everything, that ghs 13 is taxed heavily! 2 years after Covid and we are still paying Covid levy