Sarcopenia predicts death in HCC, no matter the treatment 💪
Pooled HR 1.85, I² = 0%, 92 studies, 21k patients.
Visceral fat is harmful after surgery but protective with systemic therapy 🤔
Open access in @HepCommJournal 👉 https://t.co/A2PHi0NOoD
#LiverTwitter#HCC@AASLDtweets
This year, my boyfriend Gordon and I are running the Great North Run for PSC Support, exactly 1 year after I was discharged from hospital following my liver transplant. I was diagnosed with PSC in 2020, and listed for transplant in 2023 after my health took a sudden decline.(1/4)
Artículo Original
Los niveles séricos de ácidos biliares predicen el desarrollo de hipertensión portal y várices esofágicas de alto riesgo tras una portoenterostomía de Kasai exitosa en la atresia biliar
Grimaud et al.
#LiverX
https://t.co/mPBgVqLAVm
Delighted to have presented our work on serum metabolomic signatures for cirrhosis detection and prediction in PSC at #EASLCongress2026.
Grateful to all collaborators and colleagues involved in this project.
@JesusMBanales@PMRodrigues19@RubioOmics
We’ve arrived! 🇪🇸 Martine & Mark are officially in Barcelona for the @EASLnews Congress. The PSC Support stall is set up & they've already started meeting with international patient organizations to unite our voice. Stay tuned for updates. #EASL2026#LetsBeatPSC#PatientAdvocacy
New real-life data on long-term fibrate therapy in #PSC:
✅ Biochemistry, AOM & pruritus improved
✅ Stable LSM
⚠️ Parenchymal progression on MRI despite stable strictures
📊 Adverse events in only 15%
👉 Full article available: https://t.co/BY6xv8B2Lx
#LiverX
☀️¡Buenos días! Último día de Congreso y 5º panel de comunicaciones orales, moderado por @Mariabutif y Pedro Rodrigues. Comenzamos viendo cómo ‘El perfil metabolómico sérico identifica marcadores de cirrosis en la PSC’, coordinado por @JesusMBanales y presentado por @Elisasacat:
🧬Un perfil metabolómico sérico permite distinguir #cirrosis en pacientes con PSC.
🔍De 484 metabolitos analizados, 16 se asociaron de forma independiente con cirrosis.
🧪Un modelo basado en 6 metabolitos identificó a los pacientes cirróticos con alta precisión (AUROC 0,87 en cohorte de descubrimiento).
🎯La metabolómica apunta a ser una herramienta prometedora para mejorar el 'staging' y la detección de cirrosis en PSC.
🔛A futuro: optimización del modelo y mejor selección de los pacientes, "alcanzaremos un rendimiento superior".
#51CongresoAEEH #AEEH2026
Last week in Prague, Martine Walmsley and Dr. Nora Cazzagon presented the ERN RARE-LIVER PSC Working Group’s achievements and 2026 strategy. 🇨🇿
Read the full report:
🔗 https://t.co/2wg7Aw8zjc
#PSCSupport#ERNRareLiver#RareDisease#PatientAdvocacy#LetsBeatPSC
Coordinated by @Chiarabraconi, @JesusMBanales , and @PMRodrigues19, this consensus reflects the expertise of 147 leaders from 35 countries, defining the priorities for the future of BTC research🤝
📖 Full article here: https://t.co/KHUeO5uDKs
Wondering whether your cholestatic patient might benefit from genetic testing and which genes to include? 🧬
Check out this paper 👉🏼 https://t.co/ytyyKdvrAE
Grateful to our patients and the incredible team Luisa Ronzoni @lalicristos @MCarbone_80@lucavalenti75#LiverTwitter
📢 Pronto il nuovo progetto AISF WEB ACADEMY.
Il primo webinar “Towards new second-line treatments for primary biliary cholangitis: expected outcomes and evolving perspectives” sarà il 26 giugno alle 18.
Di seguito programma e link di registrazione.
https://t.co/UBF3zUyVzU
Clarifying HCC risk in PSC 🌟
📊 Large PSC cohort: >3,000 patients across 12 centers 📌 HCC is relatively rare in PSC ⚠️ Cirrhosis and age are key risk factors for HCC in PSC
Honored to contribute alongside many colleagues to this international effort 🤝
Original Article
Cirrhosis and age are key determinants of HCC risk in individuals with primary sclerosing cholangitis: A multicenter longitudinal cohort study
Holmer et al.
#LiverX
https://t.co/nYo6Fb5G59
A special day for PSC. One phase II (in @JHepatology below, elafibranor) and one phase III (nor-UDCA, presented at the #EASLCongress) trial with potentially positive efficacy signals. Great inspiration. https://t.co/oW9YP6OF2Z
At General Session II, Pedro Miguel Rodrigues presents a Novel “3-in-1” Blood Metabolomic Test for Early Diagnosis and Risk Stratification of Primary Sclerosing Cholangitis (PSC) and Cholangiocarcinoma
This innovative metabolomic-based test offers a single-platform solution for:
✔️ Early diagnosis of PSC
✔️ Detection of cholangiocarcinoma
✔️ Risk stratification in at-risk patients
A promising advancement toward non-invasive, precision diagnostics in cholestatic liver disease and hepatobiliary cancer.
@DebbieShawcros1@AleksanderKrag
The Fourth International Consensus Guidelines on the Management of Cytomegalovirus in Solid Organ Transplantation are out now! Get the latest updates + expert insights — and don't miss the companion podcast https://t.co/CLx3QSoPvQ! #TXPforAll https://t.co/TsCWybG3rl