New from @LucieYammine Tim McGraw & colleagues. Studies in cells and mice analyzing the GIPR-Q354 variant link altered intracellular traffic of the GIPR-Q354 variant with GIP control of metabolism #weightloss#insulin secretion #obesity@WeillCornell https://t.co/PN34kOKIgy
New in @CellReports: Drs. Cyril Bourouh (@BrhCyril), @EmilieCourty, Jean-Sébastien Annicotte, & others at @PasteurLille reveal critical roles for E2f1 in #βcell function & suggest molecular crosstalk between the E2F1/pRb and GLP1R signaling pathways.
🔖 https://t.co/pOJ73it0w4
Happy to share our work with @BrhCyril ! Thank you Jean-Sébastien Annicotte for giving us the opportunity to work in a great scientific environment, and to the JSA team for their valuable contribution 👏
Very happy to share with you my thesis paper about the role of E2F1 in GLP-1R pathway in pancreatic beta cells ! Huge thanks to Dr @EmilieCourty and my thesis director Dr Jean Sébastien Annicotte ! #BetaCells#InsulinSecretion https://t.co/EhiqZNtnCa
Studies using genetically modified mice and human #islets “reveal a molecular crosstalk between the E2F1/pRb and GLP1R signaling pathways that modulates insulin secretion and glucose homeostasis” https://t.co/XdxMuy0SXd
Pancreatic β-cell specific loss of E2f1 impairs insulin secretion and β-cell identity through the epigenetic repression of non β-cell programs https://t.co/4jH2Sg8nQY #bioRxiv
Nous avons également lancé un appel à volontaires à tous les personnels pour aider nos #CIC à mener les projets de recherche clinique contre le #COVID19 . Plus d'infos ici ⬇️
https://t.co/JqFoOxrzi5
The Estall Lab is recruiting PhD students! Seeking highly motivated minds that want to dive into the metabolic basis of diabetes and cancer. Please check out our website for further details on how to apply. https://t.co/iHS4h0ebGV