Emily Mitchell

PhD student @sangerinstitute | Haematology trainee @CUH_NHS | Ageing, blood, somatic evolution.

[Emily Mitchell @Emily_LMitchell]

What happens to our blood as we get older? I am very excited to share our preprint and key findings below
https://t.co/tbD0CfAmUj

[Tom Mitchell @Tom_J_Mitchell]

I am pleased to announce our latest paper.

We report results from single cell RNA and TCR sequencing, alongside spatial RNA and genome sequencing across different regions of kidney cancers:

https://t.co/Xq53dQH4J7

[Emily Mitchell @Emily_LMitchell]

@jyoti_nangalia @Nature @sangerinstitute @SCICambridge @Cambridge_Uni Huge congrats Jyoti! Such fascinating insights and pioneering work to develop this approach :)

[Jyoti Nangalia @jyoti_nangalia]

Delighted to share my research group's latest study, published today @Nature 👉https://t.co/C3BF2Wnyw9 where we trace the life histories of blood cancer development in patients @sangerinstitute @SCICambridge @Cambridge_Uni

[Emily Mitchell @Emily_LMitchell]

@SteveStuWill That’s amazing - almost as good as the African grey parrot

[Nancy Gillis 🆖☮️ @nancykgillis]

Looking forward to this one!!

[Emily Mitchell @Emily_LMitchell]

Great work Phil, Tim and Claire - fascinating findings... happy to have been able to make a small contribution!

[Philip Robinson @drphilrobinson]

Delighted to share our paper
➡️Increased somatic mutation burdens in normal human cells due to defective DNA polymerases
https://t.co/uDo1cEz39n

Implications for our understanding of cancer risk and the somatic mutation theory of #ageing

🧵⬇️

[Addenbrooke's Charity @ACTcharity]

To celebrate #WorldLymphomaDay2021 we wanted to share this recent ACT webinar with @CUH_NHS Haematology consultant, Dr George Follows, on his research into Hodgkin Lymphoma treatments 👇👀 https://t.co/uoB6BBubkf #WLAD2021

[Emily Mitchell @Emily_LMitchell]

Congratulations Elisa!

[CRUK Cambridge Centre: Haematological Malignancies @CRUKCamHaem]

Many congratulations to PI Dr Elisa Laurenti @Cambridge_Haem @SCICambridge who is giving the Janet Rowley Award Lecture at this year's @ISEHSociety meeting

[Emily Mitchell @Emily_LMitchell]

@TimCoorens @NaturePortfolio Congratulations @TimCoorens and team :)

[Emily Mitchell @Emily_LMitchell]

Beautiful work and tweetorial

[Alex Cagan @ATJCagan]

Thrilled to share our paper on the mutational landscape of human somatic and germline cells @Nature. We integrated histology and genomics to explore the genetic diversity that develops within our bodies as we age.
https://t.co/Ep2do4JNXP
An illustrated tweetorial… [1/15]

[Emily Mitchell @Emily_LMitchell]

@FrancescoMaura4 @R_Rahbari @Nature @luiza_moore @ATJCagan @TimCoorens Huge congratulations all - what a fantastic achievement!

[Emily Mitchell @Emily_LMitchell]

@RuoyanLi @Nature Great work Ruoyan - many congratulations on this fantastic paper!

[Emily Mitchell @Emily_LMitchell]

@doctor_msc @biorxivpreprint Thanks Mike - really enjoyed working on this fascinating project together :)

[Emily Mitchell @Emily_LMitchell]

@MunshiPashna Agree! I think staying fit, healthy and happy over a lifetime could make a difference... but anyone can also be unlucky with the timing and identity of variants they by chance acquire

[Emily Mitchell @Emily_LMitchell]

What happens to our blood as we get older? I am very excited to share our preprint and key findings below
https://t.co/tbD0CfAmUj

[Emily Mitchell @Emily_LMitchell]

@DrHelenOram @doctor_msc @tinynerdster @Tom_J_Mitchell @heatherEmachado @scienceadvocacy @imartincorena @KSaebParsy @jyoti_nangalia @sangerinstitute @SCICambridge Thanks very much Helen!

[Alex Cagan @ATJCagan]

Want to learn about clonal #evolution in our #blood as we age? Check out this exciting new preprint from @Emily_LMitchell and team. Proud to have been a (very small) part of it.

[Emily Mitchell @Emily_LMitchell]

@ATJCagan Thanks so much Alex!

[Emily Mitchell @Emily_LMitchell]

@tubedonmars I wouldn't predict therapeutic plasma exchange should have a significant effect on the somatic evolutionary processes we have observed (unless removing proinflammatory cytokines in a chronic disease state)

[Emily Mitchell @Emily_LMitchell]

@FrancescoMaura4 Thanks Francesco!

[Emily Mitchell @Emily_LMitchell]

@eirinipapapetr1 We have unpublished data showing that chemotherapy can dramatically bring forward the transition to oligoclonality by significantly altering fitness effects of variants