Tim Coorens

Group Leader @emblebi | Former postdoc in @getz_lab @broadinstitute | Former PhD student @sangerinstitute | Lineage tracing, cancer genomics, human development

[Tim Coorens @TimCoorens]

Very happy and excited to announce that I'll be starting my own research group at @emblebi! The group will focus on lineage tracing, somatic evolution and the origins of cancer. Interested in doing a postdoc in the group or know someone who is? Please reach out!

[Tim Coorens @TimCoorens]

@DannGuerreroR Thanks very much @DannGuerreroR!

[SMaHT Network @SMaHTnetwork]

🧬 The SMaHT marker paper is now live in @Nature

This landmark study characterizes somatic variation across 19 tissue types from 150 nondiseased donors, laying the groundwork for future discoveries in health, aging, and disease.

Read the full paper: https://t.co/uXArDHEtHn

[Tim Coorens @TimCoorens]

Last but not least, if you're interested in somatic mutations, new technologies and computational genomics - we're hiring a postdoc in my brand new lab @emblebi!

Reach out if interested or you have any questions, and apply here: https://t.co/69nEZ7ZylY

[Tim Coorens @TimCoorens]

The cells in our bodies constantly acquire mutations. But what are the patterns of mutations across tissues? How do mutations in normal cells lead to disease? These and other questions we will tackle within the SMaHT Network, now described in @Nature
https://t.co/5c1mfZOrOR

[Tim Coorens @TimCoorens]

This effort would be impossible without the work of many hundreds of people, including the scientists, the NIH staff, and - of course - the donors and their family. A very exciting time to study somatic evolution and I can't wait to see what the next years bring.

[Tim Coorens @TimCoorens]

@EricTopol @Nature Thanks for highlighting the SMaHT effort @EricTopol! Fantastically exciting project, immensely grateful to be part of it and can't wait to see what the next few years hold.

[Tim Coorens @TimCoorens]

@Noelia__DF @MobileGenomes @emblebi Thanks very much for the kind words, @Noelia__DF! Very much enjoyed my days in Santiago

[Profesor Tubio - Mobile Genomes Lab @MobileGenomes]

This Monday at CIMUS @TimCoorens from @emblebi

[Isidro Cortes-Ciriano @isidrolauscher]

Thrilled to see #SAVANA out in @naturemethods🥳 SAVANA detects haplotype-resolved somatic SVs and copy number aberrations (SCNAs) and infers tumour purity & ploidy in clinical samples using long-read sequencing with or WITHOUT a matched germline control 👇https://t.co/AdZhqHUsDb

[JB Alberge @JbAlberge]

1/ 🧵Check out our new study in @NatureGenet, which examines how precancerous conditions (MGUS/SMM) evolve into Multiple Myeloma, and offers new computational methods to predict progression risk and model cancer evolution.

https://t.co/IHnN87QKTk

[Genome Research @genomeresearch]

Call for Papers! @genomeresearch is now encouraging submissions for a Special Issue on The Genetics and Genomics of Somatic Mosaicism, Guest Edited by Drs. @giladevrony, @EAliceLee2, and @R_Rahbari. https://t.co/jKuoADbJec #BOG25 #KSMosaicism25 #MITS25 #somaticmosaicism

[Mia Petljak @miapetljak]

@AACR Seeing friends and gushing about our shared love for DNA 🤓🧬😃🤟@TimCoorens @imartincorena @ivazquezgarcia #AACR25

[Mia Petljak @miapetljak]

🚨OPEN POSTDOC
POSITION in our brand new lab space by Madison Sq NYC ! 🌆🧬🔬

Do experiments, learn computation, and uncover drivers of a major mutational process affecting >50% of cancers, driving therapy resistance & impacting immunotherapy responses👇

https://t.co/RT7WEtr1Dy

[Joseph G. Gleeson @jogleeson_ucsd]

Check out our new paper in @nature https://t.co/cI3YCh7X1g. We report genetic mechanisms of neural tube defects in patients. Spina bifida is also known as meningomyelocele (MM). Prior family-based and association studies found few linked genes, so we took a different approach.

[Tim Coorens @TimCoorens]

@GiovannaMantica Thanks very much, Giovanna!

[Eric Topol @EricTopol]

This new paper @Nature today on the genesis and evolution of stomach cancer goes against the alt-model
https://t.co/hsjIMmVKBs
https://t.co/IABPCWKgK5

[Wellcome Sanger Institute @sangerinstitute]

For the first time, scientists have analysed mutations in stomach lining tissue to reveal the earliest stages of cancer.

The team also uncovered a potential new cause of stomach cancer, which needs further research 🔎

https://t.co/RZ5NXdMmHS