Our latest study, led by @Homaira_H. Hard to study #macrophages (MFs) in early human heart development (no tissue). Homaira integrated human ES-derived-MFs into beating cardiac microtissues & improved🫀function. https://t.co/dZ45GiNEkH. #cardioimmunology #regeneration.
100s labs ordered the wrong "p16" antibody.
They wanted to study p16-INK4a, but bought p16-ARC antibodies.
312 papers got it wrong.
Now the literature is polluted with false mechanistic pathways.
Validate your reagents. But also read the datasheet and use your brain.
Very excited to share our latest paper, published as a Research Letter in Circulation. We show a significant role for adaptive immunity in arrhythmogenic right ventricular cardiomyopathy.
https://t.co/O2BeEsDUgQ
Sepsis is a balancing act: too little immunity fails to control infection, too much causes tissue damage. Our @ScienceMagazine paper reveals one mechanism behind this tradeoff.
https://t.co/D0IXKZyjfu
Using smartphone facial video clips with AI to passively and accurately get heart rate, across all skin pigmentation groups @nature
"This is the first demonstration that smartphones
can be used to monitor both HR and daily RHR passively during normal personal phone use in the real world."
https://t.co/cYz94D2ZGU
There hasn't previously been a treatment vs pancreatic cancer this successful. Striking improved (a > doubling) survival results @NEJM and @ASCO today with daraxonrasib, which also became available via an FDA approved early access program and began shipping to physicians this week @RevMedicines
https://t.co/e04jqJMPw0
Review @SciImmunology
The transcriptional and epigenetic regulation of macrophage differentiation, specialization, and activation in health and disease
https://t.co/Woxrw6xR6N
With aging, cells lose their identity and undergo a mesenchymal drift. Reversing this drift may be a way to mitigate aging and promote healthspan. A new @CellCellPress review
https://t.co/fr4N6b75Im
Important #LongCovid finding of auto-antibodies in patients directed to neural tissue, and then, by transferring the antibodies, recapitulated the disease symptoms in mice @CellCellPress@VirusesImmunity@putrinolab
https://t.co/s4bSXjTVe6
In a paper just published in @sciencemagazine, we teamed up with @teichlab to construct the most detailed atlas to date of hormone production and action in humans at cellular resolution. (1/8)
Link: https://t.co/5iPOCq9yfu