Chad Johnston

Assistant professor and CPRIT Scholar at the Baylor College of Medicine in Houston, starting Jan 2022. Discovery and directed evolution of natural products 🦠

[Chad Johnston @EvolvedChem]

Happy to finally be announcing that I’ll be joining the Baylor College of Medicine as an assistant professor and CRPIT scholar starting January 2022!

[Chad Johnston @EvolvedChem]

Well, it took a little longer than expected, but we're happy to share our lab's first paper. Thanks to the reviewers and editors at JACS for sticking with us through a surprisingly weird story 😅. Science never changes.
https://t.co/cXz6Ey3HrU

[Chad Johnston @EvolvedChem]

@med_chemist "Have a HTS return no useful hits" should have a trigger warning.

[Chad Johnston @EvolvedChem]

@vhvsynth I'm dying to know: can you taste the spice in the air when you're making this thing? Awesome work btw!

[Chad Johnston @EvolvedChem]

@wildtypeMC Comments already have quotes-for-everything and NEB. You'll need to also do the math on vendor pricing to find the best deals. Glassware and other odds and ends can generally be had from older labs that'll give them away for free. Buy used if you're brave or can fix things.

[Chad Johnston @EvolvedChem]

@GeoSantiagoM @wildtypeMC This. I think there's a cap of $5k or something, but it's significant savings.

[Chad Johnston @EvolvedChem]

@ZachReitzPhD Is the beta-hydroxy histidine new? Don't know that I've seen that in siderophores before...

[Chad Johnston @EvolvedChem]

@MoleculesGoHard I'm stealing this and using it for all molecules of interest from now on. Thanks.

[Chad Johnston @EvolvedChem]

@wildtypeMC Black Vans lows are the only acceptable shoe for new PIs. Change my mind.

[Chad Johnston @EvolvedChem]

It's not necessarily science, but I'm exposed through my better half. Kyla Scanlon is the best finance follow out there.

[Kyla Scanlon @kylascan]

Jackson Hole Recap

[Nature Chemical Biology @nchembio]

A new paper from Kim Lewis identified a natural product Evybactin targeting DNA gyrase and killing Mycobacterium tuberculosis via a selective transport mechanism. Free to read link at https://t.co/3hOB9XYKRa

[Chad Johnston @EvolvedChem]

New LCMS just dropped.

[Chad Johnston @EvolvedChem]

First Johnston lab outing! Great time with the team, plus I learned I can't take group selfies AND look normal. Maybe one day.

[Chad Johnston @EvolvedChem]

Me - a new PI with a freezer already full of bacterial extracts

[60% Water By Mass @MoleculesGoHard]

Industry has spoiled me

[Chad Johnston @EvolvedChem]

@SophieLNixon @katcoyte @BiotechDixon @BrockhurstLab @knightjjar @Hepworth_Lab @OfficialUoM @SustainableUoM @DigitalUoM Congrats!

[Chad Johnston @EvolvedChem]

Hey aspiring PIs! Looking for a Prof position that comes with a cool neighbour? My department is hiring !

Come see everything Baylor, Houston, and the Texas Med Centre have to offer! (spoiler: it's a lot)

https://t.co/bWz4HViZAy

[Chad Johnston @EvolvedChem]

@14Kountz Geosmin and a gradient of prodigiosin (plus a secret ingredient... that appears to be however close they are to the incubator air vent)

[Chad Johnston @EvolvedChem]

Taste the Streptomyces rainbow (but really you probably shouldn't even if it's BSL1... but maybe?)

[Chad Johnston @EvolvedChem]

@wildtypeMC *laughs in Houston*

[Chad Johnston @EvolvedChem]

@NadineZiemert To be fair, he does clarify many natural product mysteries!

[Chad Johnston @EvolvedChem]

@NadineZiemert Jon Clarify stays winning!